Detailed information of TA system TA079207

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): pmenTA/darT(toxin)
• Location: 1021232..1022946
• Replicon: chromosome
• Accession: NZ_CP022550
• Organism: Aeromonas salmonicida strain A527

Toxin (Protein)

• Gene name: pmenT
• Uniprot ID: -
• Locus tag: CHQ57_RS04940
• Protein ID: WP_099991772.1
• Coordinates: 1021232..1021885 (+)
• Length: 218 a.a.

Antitoxin (Protein)

• Gene name: pmenA
• Uniprot ID: -
• Locus tag: CHQ57_RS04945
• Protein ID: WP_099991774.1
• Coordinates: 1021882..1022946 (+)
• Length: 355 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHQ57_RS04925	1016553..1016999	+	447	WP_043852095.1	hypothetical protein	-
CHQ57_RS04930	1017185..1019632	+	2448	WP_099991766.1	type I restriction-modification system subunit M	-
CHQ57_RS04935	1019632..1020966	+	1335	WP_099991769.1	restriction endonuclease subunit S	-
CHQ57_RS04940	1021232..1021885	+	654	WP_099991772.1	DUF4433 domain-containing protein	Toxin
CHQ57_RS04945	1021882..1022946	+	1065	WP_099991774.1	macro domain-containing protein	Antitoxin
CHQ57_RS04950	1023021..1025285	+	2265	Protein_931	HsdR family type I site-specific deoxyribonuclease	-
CHQ57_RS04955	1025296..1026714	-	1419	WP_005327996.1	IS66-like element ISUnCu16 family transposase	-
CHQ57_RS04960	1026834..1027691	+	858	Protein_933	restriction endonuclease subunit R	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	1025296..1026702	1406

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• ssDNA thymidine ADP-ribosyltransferase, DarT (17-216)

Antitoxin

• Macro domain (18-131)

Sequences

Toxin

Protein

• Length: 218 a.a.
• Molecular weight: 25344.93 Da
• Isoelectric Point: 6.8262

>T79207 WP_099991772.1 NZ_CP022550:1021232-1021885 [Aeromonas salmonicida]
MAYDYSQSLNPEKALIFRIVHRDNLEWILTHGLWAGNGQQQNPHWVHIGLPELIAKRARHPVPLAPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPQRENDEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYVDLGDLGRIDWPLLQRRDFKRDADDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR

Nucleotide

• Length: 654 bp

>T79207 NZ_CP022550:1021232-1021885 [Aeromonas salmonicida]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGGAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAACCTGGAGTG
GATCCTGACCCATGGCCTGTGGGCGGGAAATGGTCAGCAGCAAAACCCGCACTGGGTGCATATCGGGCTGCCGGAGCTGA
TTGCCAAGCGCGCGCGCCATCCGGTGCCGCTGGCGCCTTACGGCGTGTTGAATGACTATGTGCCCTTCTACTTCACGCCG
TTTTCGCCCATGCTCAGCAATATTCACTCGGGGCGCGGTGTTCCCCAGCGTGAAAATGATGAAATCCTGATCCTGGTTTC
CAGCCTGCATCGCATGGCTGAACTGGGGCTACCGTTTGTGTTTACCGATAGCCATGCCTATTACCAGTGGGCCAATTTCT
ATGTCGACCTTGGCGATCTGGGGCGGATTGACTGGCCACTGTTGCAGCGCCGTGATTTCAAGCGTGATGCGGACGATTTG
AGCAAGCTGGAACGCTATCAGGCCGAGGCCTTGATCCATCAACATTGCCCCATCGAGGCGTTGCTGGGCGTGGTGTGTTA
CAACGAAGAGATAAAGAACCGCGTGGAACAATGCATGAATCGGGTGGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin

Protein

• Length: 355 a.a.
• Molecular weight: 39574.66 Da
• Isoelectric Point: 6.7554

>AT79207 WP_099991774.1 NZ_CP022550:1021882-1022946 [Aeromonas salmonicida]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANVRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSSQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKQELAVYLHTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQHGLV

Nucleotide

• Length: 1065 bp

>AT79207 NZ_CP022550:1021882-1022946 [Aeromonas salmonicida]
ATGATTCGATATACAACAGGCAATCTGCTGGATGCTCCGGTGGAAGCGCTGGTGAATACCGTCAACACCGTCGGTGTCAT
GGGCAAGGGGATCGCCTTGATGTTCAAGGAGCGGTTCCCGGCCAATGTGCGCGCCTATGCCGAGGCGTGCAAACAGGGTG
ATGTCGTCACCGGCAAGATGTTTATTACCCAGACGGGTGAGCTGCTGGGGCCGCGCTGGATCGTGAATTTTCCGACCAAA
CAGCACTGGCGCAATCCGGCACAGATGGCGTGGATCCAGGATGGTTTGCAGGATCTGCGGGCCTGGTTACAGGCGCAGCA
GGTCTCCTCGATTGCCATTCCGCCGCTGGGGGCTGGCAACGGTGGTCTGCCTTGGCCAGAGGTCAAACAGGCGATTGAAA
CGGCACTGGGCGATCTGGATATCGATATCCTGCTCTATGAGCCCAGTAGCCAATACCAAAATGTGGCCAAGCGCGGCGGG
GTGGCGGAGCTGACTCCGGCTCGGGCCCTGATTGCTGAACTGGTACGTCGCTACTGGTTTTTAGGGATGGAGTGCAGCTT
GCTGGAAATCCAGAAGCTGGCCTGGTTTCTGGCTCGGGTCATTGGCCGTAACCCGCTGGGGGATCCGCTGCAGTTGCAGT
TTAAGGCCCATCGTTATGGCCCTTATGCCAACAATCTGACTCATCTGCTCAATGCGATGGACGGCAGTTATCTGCAGTCC
GACAAGCGCATCCCGGATAGCAAGCCGTTTGATGTCATCTGGTTTAATGAGGCCAAAAAACAAGAGCTTGCCGTTTATCT
CCATACTGAGGCCAAAGCATTTTTACCGATACTGGAGCAGACGACCGCGTTAATCGACGGTTTTGAGTCGCCCTATGGCA
TGGAGTTATTGGCCACGGTCGATTGGTTGATCGCCGAAGAGGGCTGTGCGCCGACACTGAGCGCGCTGCGCGAGGGGTTG
CACCGCTGGCCAGCGGGAACCCCGTGGGGTGAGCGCAAGGCGCGGCTGTTTGATGATCGCAGTCTGCAGATCGCCTTGAC
CCGTTTGCAGCATGGATTGGTGTAA