Detailed information of TA system TA079205

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/ParE-CC2985
• Location: 346800..347325
• Replicon: chromosome
• Accession: NZ_CP022548
• Organism: Sphingorhabdus sp. YGSMI21

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: CHN51_RS01630
• Protein ID: WP_100092454.1
• Coordinates: 346800..347084 (-)
• Length: 95 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: -
• Locus tag: CHN51_RS01635
• Protein ID: WP_100092455.1
• Coordinates: 347077..347325 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHN51_RS01615	343407..344231	+	825	WP_100092451.1	type I methionyl aminopeptidase	-
CHN51_RS01620	344349..345518	-	1170	WP_100092452.1	DUF4263 domain-containing protein	-
CHN51_RS01625	345813..346721	+	909	WP_100092453.1	hypothetical protein	-
CHN51_RS01630	346800..347084	-	285	WP_100092454.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CHN51_RS01635	347077..347325	-	249	WP_100092455.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
CHN51_RS01640	347481..347819	+	339	WP_100092456.1	hypothetical protein	-
CHN51_RS01645	347890..348738	-	849	WP_100095364.1	OmpA family protein	-
CHN51_RS01650	349105..350193	+	1089	WP_100095365.1	GAF domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	336214..355816	19602

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-92)

Antitoxin

• Antitoxin ParD (7-72)

Sequences

Toxin

Protein

• Length: 95 a.a.
• Molecular weight: 10982.44 Da
• Isoelectric Point: 6.2241

>T79205 WP_100092454.1 NZ_CP022548:c347084-346800 [Sphingorhabdus sp. YGSMI21]
MADLRLSRRAASDLAEIADYTIAEFGIDQARLYRDQFQACFRSLLENPQLGSSAEEVAPGLRRIRQQAHVVFYRVERDEL
FIVRVLHHSMDFER

Nucleotide

• Length: 285 bp

>T79205 NZ_CP022548:c347084-346800 [Sphingorhabdus sp. YGSMI21]
ATGGCTGACCTGCGCCTCAGCAGGCGCGCCGCAAGCGATCTGGCCGAAATAGCCGATTACACCATTGCCGAATTCGGCAT
CGATCAGGCGCGGCTCTATCGCGACCAGTTTCAAGCCTGTTTCCGGTCCCTGCTGGAGAATCCGCAGCTCGGCAGCAGCG
CCGAGGAGGTCGCCCCGGGATTGCGCCGTATTCGTCAGCAGGCGCATGTTGTGTTTTACAGGGTTGAGCGGGATGAGCTG
TTTATCGTGCGGGTGCTGCATCACAGCATGGATTTTGAGCGGTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 8954.77 Da
• Isoelectric Point: 4.4287

>AT79205 WP_100092455.1 NZ_CP022548:c347325-347077 [Sphingorhabdus sp. YGSMI21]
MATVRKTITLSESQDAWIKSRIAGGAFTNDSEYIRDLVKRDQSQEDRLATLRAAIAEGLDSGTSDQSLDDIWSAAEDRAA
HG

Nucleotide

• Length: 249 bp

>AT79205 NZ_CP022548:c347325-347077 [Sphingorhabdus sp. YGSMI21]
ATGGCCACCGTCCGCAAAACCATCACGCTCAGCGAGAGCCAGGACGCATGGATAAAATCCCGGATCGCTGGCGGTGCCTT
TACCAATGATAGCGAATATATCCGCGATCTGGTCAAGCGCGACCAGTCGCAGGAAGACCGGCTCGCCACTTTAAGAGCGG
CGATAGCCGAGGGTCTCGACAGCGGCACCAGCGACCAGTCGCTGGACGATATATGGAGCGCCGCCGAAGACCGCGCTGCC
CATGGCTGA