Detailed information of TA system TA079146

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): ccdAB/CcdA(antitoxin)
• Location: 13107..13632
• Replicon: plasmid unnamed1
• Accession: NZ_CP022492
• Organism: Salmonella enterica subsp. enterica serovar Saintpaul strain SA20031783

Toxin (Protein)

• Gene name: ccdB
• Uniprot ID: -
• Locus tag: CHC80_RS24265
• Protein ID: WP_050316698.1
• Coordinates: 13107..13412 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: ccdA
• Uniprot ID: A0A6C0NE25
• Locus tag: CHC80_RS24270
• Protein ID: WP_032934863.1
• Coordinates: 13414..13632 (-)
• Length: 73 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CHC80_RS24235	8475..8666	+	192	WP_093980893.1	hypothetical protein	-
CHC80_RS24240	8890..9546	-	657	WP_093980980.1	MgtC/SapB family protein	-
CHC80_RS24245	10188..10967	-	780	WP_093980894.1	site-specific integrase	-
CHC80_RS24250	10972..11505	-	534	WP_137429006.1	hypothetical protein	-
CHC80_RS24255	11517..11903	-	387	WP_093980896.1	hypothetical protein	-
CHC80_RS24260	12066..12956	-	891	WP_093980897.1	hypothetical protein	-
CHC80_RS24265	13107..13412	-	306	WP_050316698.1	type II toxin-antitoxin system toxin CcdB	Toxin
CHC80_RS24270	13414..13632	-	219	WP_032934863.1	type II toxin-antitoxin system antitoxin CcdA	Antitoxin
CHC80_RS24275	14335..14958	+	624	WP_093980898.1	DNA-binding protein	-
CHC80_RS24280	15512..16447	+	936	WP_093980899.1	RepB family plasmid replication initiator protein	-
CHC80_RS24285	17008..17235	-	228	WP_093980900.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..131583	131583

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (2-116)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 15030.03 Da
• Isoelectric Point: 5.5500

>T79146 WP_050316698.1 NZ_CP022492:c13412-13107 [Salmonella enterica subsp. enterica serovar Saintpaul]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 306 bp

>T79146 NZ_CP022492:c13412-13107 [Salmonella enterica subsp. enterica serovar Saintpaul]
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Antitoxin

Protein

• Length: 73 a.a.
• Molecular weight: 10761.91 Da
• Isoelectric Point: 5.5500

>AT79146 WP_032934863.1 NZ_CP022492:c13632-13414 [Salmonella enterica subsp. enterica serovar Saintpaul]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Nucleotide

• Length: 219 bp

>AT79146 NZ_CP022492:c13632-13414 [Salmonella enterica subsp. enterica serovar Saintpaul]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Structures

Antitoxin

• AlphaFold DB: A0A6C0NE25