Detailed information of TA system TA079103

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafN(antitoxin)
• Location: 1024072..1024637
• Replicon: chromosome
• Accession: NZ_CP022469
• Organism: Vibrio anguillarum strain MHK3

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CG015_RS18410
• Protein ID: WP_129533170.1
• Coordinates: 1024072..1024359 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CG015_RS18415
• Protein ID: WP_164996843.1
• Coordinates: 1024356..1024637 (-)
• Length: 94 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CG015_RS18360	1019833..1020093	-	261	WP_129533243.1	DUF3709 domain-containing protein	-
CG015_RS18365	1019976..1020279	-	304	Protein_895	disulfide bond formation protein DsbD	-
CG015_RS18370	1020351..1020602	-	252	WP_129533242.1	TIGR03643 family protein	-
CG015_RS18375	1021318..1021683	-	366	WP_129533167.1	hypothetical protein	-
CG015_RS18380	1021686..1022057	-	372	WP_129533168.1	hypothetical protein	-
CG015_RS18385	1022603..1022734	-	132	WP_129533169.1	DUF3265 domain-containing protein	-
CG015_RS18390	1023058..1023180	-	123	WP_129533244.1	exlusion protein FxsA	-
CG015_RS18400	1023468..1023590	-	123	WP_129533245.1	DUF3265 domain-containing protein	-
CG015_RS18405	1023934..1024062	-	129	WP_108695303.1	DUF3265 domain-containing protein	-
CG015_RS18410	1024072..1024359	-	288	WP_129533170.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CG015_RS18415	1024356..1024637	-	282	WP_164996843.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CG015_RS18420	1024728..1024838	-	111	WP_129533246.1	DUF3265 domain-containing protein	-
CG015_RS18435	1025679..1025801	-	123	WP_129533247.1	DUF3265 domain-containing protein	-
CG015_RS18440	1025785..1026390	-	606	WP_129533172.1	hypothetical protein	-
CG015_RS18450	1026536..1026934	-	399	WP_021706447.1	VOC family protein	-
CG015_RS19060	1027172..1027714	-	543	WP_207204988.1	hypothetical protein	-
CG015_RS19025	1028296..1028430	-	135	WP_164996854.1	DUF3265 domain-containing protein	-
CG015_RS18465	1028685..1029038	-	354	WP_207204989.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	852173..1046590	194417

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (9-74)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 10911.68 Da
• Isoelectric Point: 5.6023

>T79103 WP_129533170.1 NZ_CP022469:c1024359-1024072 [Vibrio anguillarum]
MKVVWSPLALQKLGDAAEFIALDNPSAAEKWVNDVFDKTELLGSMPEMGRMVPEIPHTNYREIIFGHYRIIYSLGLEIRV
LTVRNCRQLLTEHDV

Nucleotide

• Length: 288 bp

>T79103 NZ_CP022469:c1024359-1024072 [Vibrio anguillarum]
ATGAAAGTAGTTTGGTCACCTCTAGCGTTACAAAAACTTGGTGATGCCGCAGAGTTTATTGCTTTGGATAACCCCTCAGC
TGCAGAAAAGTGGGTGAATGATGTGTTCGACAAAACGGAATTGCTCGGCTCAATGCCAGAAATGGGCCGCATGGTTCCTG
AAATACCTCATACGAACTACCGTGAAATAATTTTTGGCCATTACCGCATTATTTATAGTTTGGGCCTCGAAATACGTGTT
CTAACAGTCCGTAACTGTCGTCAATTGCTCACGGAACATGATGTGTGA

Antitoxin

Protein

• Length: 94 a.a.
• Molecular weight: 10361.93 Da
• Isoelectric Point: 5.1548

>AT79103 WP_164996843.1 NZ_CP022469:c1024637-1024356 [Vibrio anguillarum]
MSRIHLDQDIQPLSEFRAGVASFIKQINETRRPLVITQRGKGVAVVLDVAEYEAMQEKIELLEEMRTAEAQLAAGLGVSN
EDARSQILGRIIK

Nucleotide

• Length: 282 bp

>AT79103 NZ_CP022469:c1024637-1024356 [Vibrio anguillarum]
ATGAGCCGTATTCACCTTGATCAAGATATTCAGCCTTTGTCTGAGTTCCGTGCTGGCGTTGCATCATTTATCAAACAGAT
CAATGAGACTCGTCGACCATTAGTTATTACACAACGAGGTAAAGGTGTAGCCGTTGTTCTTGACGTTGCGGAGTATGAAG
CAATGCAAGAGAAAATCGAATTACTTGAAGAAATGCGTACTGCAGAAGCTCAATTGGCTGCAGGTTTGGGTGTATCAAAC
GAAGATGCTCGTTCACAAATTCTGGGACGCATCATCAAATGA