Detailed information of TA system TA079102

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-yefM/YoeB-RelB
• Location: 990881..991391
• Replicon: chromosome
• Accession: NZ_CP022469
• Organism: Vibrio anguillarum strain MHK3

Toxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CG015_RS18100
• Protein ID: WP_129533152.1
• Coordinates: 990881..991144 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: A0A7X5B7D9
• Locus tag: CG015_RS18105
• Protein ID: WP_009836585.1
• Coordinates: 991137..991391 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CG015_RS18085	987181..987648	-	468	WP_019281393.1	hypothetical protein	-
CG015_RS18095	990412..990648	+	237	WP_013867767.1	hypothetical protein	-
CG015_RS18100	990881..991144	-	264	WP_129533152.1	Txe/YoeB family addiction module toxin	Toxin
CG015_RS18105	991137..991391	-	255	WP_009836585.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
CG015_RS18125	993104..993286	-	183	WP_000923148.1	DUF645 family protein	-
CG015_RS18145	995136..995882	-	747	WP_164996839.1	transporter substrate-binding domain-containing protein	-
CG015_RS18155	996097..996387	-	291	WP_129533104.1	YkgJ family cysteine cluster protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integron	-	-	852173..1046590	194417

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (6-87)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10360.67 Da
• Isoelectric Point: 7.9816

>T79102 WP_129533152.1 NZ_CP022469:c991144-990881 [Vibrio anguillarum]
MSSRLLSWTDESWNDYVYWQTQDKKTLKRINKLITDAKRSPFEGIGKPEPLKENLSDFWSRRIDDANRLVYAVDDSAITI
ISCRYHY

Nucleotide

• Length: 264 bp

>T79102 NZ_CP022469:c991144-990881 [Vibrio anguillarum]
ATGAGTAGTCGTTTATTATCTTGGACTGATGAATCTTGGAATGATTATGTTTATTGGCAGACGCAAGACAAGAAAACACT
TAAACGTATAAATAAACTCATCACGGATGCTAAGCGTTCTCCTTTCGAAGGCATAGGTAAACCTGAGCCACTAAAAGAAA
ACTTATCTGATTTTTGGTCGCGACGAATAGACGATGCGAATAGGTTAGTTTATGCGGTTGATGATAGTGCTATCACGATT
ATTTCTTGCCGTTATCACTATTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9462.65 Da
• Isoelectric Point: 5.5802

>AT79102 WP_009836585.1 NZ_CP022469:c991391-991137 [Vibrio anguillarum]
MRIVSFTEARNSLKSVLDAVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPANAEHLHRSIAQFKAGKVSQRD
LIDE

Nucleotide

• Length: 255 bp

>AT79102 NZ_CP022469:c991391-991137 [Vibrio anguillarum]
ATGAGAATTGTATCTTTTACAGAAGCTAGAAATAGCTTGAAGAGCGTTTTGGATGCTGTTGTTAATGACGCAGATACAAC
CGTGATCACACGTCGTGATTCTGAAGATGCCGTTGTTATGTCACTGGATTATTACAATAGCTTAATGGAAACGGTTCATT
TACTTCGTTCGCCGGCAAATGCTGAGCACTTACATCGTTCAATTGCTCAATTTAAAGCGGGTAAGGTGAGCCAAAGAGAT
TTAATCGATGAGTAG

Structures

Antitoxin

• AlphaFold DB: A0A7X5B7D9