Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3412164..3412398 Replicon chromosome
Accession NZ_CP022457
Organism Shigella sonnei strain 2015C-3566

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3412294..3412397 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3412164..3412398 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B9128_RS18600 3408719..3409381 - 663 WP_000944256.1 exodeoxyribonuclease X -
B9128_RS18605 3409405..3410061 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
B9128_RS18610 3410163..3410393 - 231 WP_000916763.1 DNA polymerase III subunit theta -
B9128_RS18615 3410532..3410906 + 375 WP_000168735.1 CopC domain-containing protein YobA -
B9128_RS18620 3410910..3411782 + 873 WP_000879296.1 copper homeostasis membrane protein CopD -
B9128_RS18625 3411795..3412136 + 342 WP_000976476.1 YebY family protein -
- 3412164..3412398 - 235 - - Antitoxin
- 3412294..3412397 + 104 - - Toxin
B9128_RS18630 3412529..3413605 - 1077 WP_001189101.1 phage integrase Arm DNA-binding domain-containing protein -
B9128_RS18635 3413642..3413887 - 246 Protein_3317 IS1 family transposase -
B9128_RS18645 3415221..3415675 - 455 Protein_3319 IS1-like element IS1A family transposase -
B9128_RS18650 3415704..3415964 - 261 WP_077447296.1 excisionase -
B9128_RS18655 3416109..3417265 + 1157 WP_087879964.1 IS3-like element IS600 family transposase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T79087 NZ_CP022457:3412294-3412397 [Shigella sonnei]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT79087 NZ_CP022457:c3412398-3412164 [Shigella sonnei]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References