Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 6832..7354 Replicon plasmid pD90-3
Accession NZ_CP022453
Organism Salmonella enterica subsp. enterica serovar Indiana strain D90

Toxin (Protein)


Gene name relE Uniprot ID D0QMR1
Locus tag CGL53_RS26080 Protein ID WP_000220561.1
Coordinates 7073..7354 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID G3CAG1
Locus tag CGL53_RS26075 Protein ID WP_000121743.1
Coordinates 6832..7083 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGL53_RS26055 2955..3308 - 354 WP_024129958.1 DNA distortion protein 3 -
CGL53_RS26060 3445..3891 - 447 WP_001074384.1 hypothetical protein -
CGL53_RS26065 3895..4737 - 843 WP_000435064.1 replication initiation protein -
CGL53_RS26070 4758..5597 - 840 WP_024129959.1 replication initiation protein -
CGL53_RS26075 6832..7083 + 252 WP_000121743.1 plasmid stabilization protein Antitoxin
CGL53_RS26080 7073..7354 + 282 WP_000220561.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CGL53_RS26630 7593..7685 - 93 Protein_9 IS6 family transposase -
CGL53_RS26085 7851..9050 - 1200 WP_000948429.1 IS91 family transposase -
CGL53_RS26090 9060..9248 - 189 WP_000957857.1 hypothetical protein -
CGL53_RS26095 9368..10798 + 1431 Protein_12 IS4-like element IS50R family transposase -
CGL53_RS26100 10827..11621 + 795 WP_000572405.1 aminoglycoside O-phosphotransferase APH(3')-IIa -
CGL53_RS26105 11642..11878 + 237 Protein_14 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..38911 38911


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 12066.38 Da        Isoelectric Point: 12.7685

>T79055 WP_000220561.1 NZ_CP022453:7073-7354 [Salmonella enterica subsp. enterica serovar Indiana]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKK

Download         Length: 282 bp

>T79055 NZ_CP022453:7073-7354 [Salmonella enterica subsp. enterica serovar Indiana]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 10784.64 Da        Isoelectric Point: 12.7191

>AT79055 WP_000121743.1 NZ_CP022453:6832-7083 [Salmonella enterica subsp. enterica serovar Indiana]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKK

Download         Length: 252 bp

>AT79055 NZ_CP022453:6832-7083 [Salmonella enterica subsp. enterica serovar Indiana]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3S5I302

Antitoxin

Source ID Structure
AlphaFold DB A0A3S5I301

References