Detailed information of TA system TA079028

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): yeeUV (cbtA-cbeA)/CbtA-CbeA
• Location: 2797094..2797800
• Replicon: chromosome
• Accession: NZ_CP022427
• Organism: Pantoea ananatis strain YJ76

Toxin (Protein)

• Gene name: yeeV
• Uniprot ID: -
• Locus tag: B7764_RS13300
• Protein ID: WP_089517509.1
• Coordinates: 2797094..2797414 (-)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yeeU
• Uniprot ID: -
• Locus tag: B7764_RS13305
• Protein ID: WP_089517510.1
• Coordinates: 2797450..2797800 (-)
• Length: 117 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B7764_RS13265	2792337..2792783	-	447	WP_013024955.1	hypothetical protein	-
B7764_RS24555	2792966..2793103	+	138	WP_155250602.1	hypothetical protein	-
B7764_RS13270	2793236..2793472	-	237	WP_024471184.1	DUF4282 domain-containing protein	-
B7764_RS13275	2793539..2793772	-	234	WP_013024953.1	terminase small subunit	-
B7764_RS13280	2793793..2794230	+	438	WP_024471185.1	hypothetical protein	-
B7764_RS13290	2794799..2796046	-	1248	WP_089517507.1	PD-(D/E)XK nuclease family protein	-
B7764_RS13295	2796146..2796979	-	834	WP_089517508.1	DUF4942 domain-containing protein	-
B7764_RS13300	2797094..2797414	-	321	WP_089517509.1	TA system toxin CbtA family protein	Toxin
B7764_RS13305	2797450..2797800	-	351	WP_089517510.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
B7764_RS13310	2797823..2798044	-	222	WP_089517511.1	DUF987 domain-containing protein	-
B7764_RS13315	2798058..2798537	-	480	WP_089517819.1	DNA repair protein RadC	-
B7764_RS13320	2798548..2799030	-	483	WP_089517512.1	antirestriction protein	-
B7764_RS24825	2799148..2799291	-	144	WP_193553021.1	hypothetical protein	-
B7764_RS13330	2799383..2800219	-	837	WP_089517513.1	hypothetical protein	-
B7764_RS13335	2800561..2800737	-	177	WP_157982878.1	hypothetical protein	-
B7764_RS13340	2800811..2801215	-	405	WP_089517515.1	hypothetical protein	-
B7764_RS13345	2801427..2802314	-	888	WP_089517820.1	50S ribosome-binding GTPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2793509..2824520	31011

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (12-105)

Antitoxin

• Antitoxin CbeA (12-111)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 11876.49 Da
• Isoelectric Point: 5.9568

>T79028 WP_089517509.1 NZ_CP022427:c2797414-2797094 [Pantoea ananatis]
MHISSVSATVPVSSRLSPVQVWQQLLTYLLEHHYGLTLNDSPFHDGAAIEEHIEAGITLADAVNFLVERYELVRIDRKGF
TCQEQTPFLTATDILRARRATGLINT

Nucleotide

• Length: 321 bp

>T79028 NZ_CP022427:c2797414-2797094 [Pantoea ananatis]
ATGCATATTTCATCTGTATCGGCCACGGTGCCGGTTTCGTCACGCCTGTCGCCCGTACAGGTCTGGCAGCAATTGTTAAC
GTATCTGTTGGAACATCATTACGGCTTGACACTTAACGACTCACCATTTCATGACGGCGCGGCCATTGAGGAGCATATCG
AAGCGGGAATCACGCTTGCCGATGCGGTTAATTTTCTGGTGGAACGCTATGAACTGGTACGCATAGACCGCAAAGGATTT
ACATGCCAGGAGCAGACACCATTTCTGACTGCGACCGATATTCTCAGAGCCAGGCGAGCTACCGGATTAATAAATACCTG
A

Antitoxin

Protein

• Length: 117 a.a.
• Molecular weight: 13003.90 Da
• Isoelectric Point: 7.8242

>AT79028 WP_089517510.1 NZ_CP022427:c2797800-2797450 [Pantoea ananatis]
MKNTKNHDIADPWWGLKPTVTPCFGARLVQEGNRLHYLADRAGVTGSFIPKQLQKLDQAFPLFVEQLENMLRSGELNPHQ
QHQVTIHLAGLTCIADTRGSCGYVYIAIYPQVSVTQ

Nucleotide

• Length: 351 bp

>AT79028 NZ_CP022427:c2797800-2797450 [Pantoea ananatis]
ATGAAAAACACCAAAAACCATGATATTGCCGACCCTTGGTGGGGACTTAAACCCACCGTCACGCCTTGCTTTGGCGCACG
ACTGGTGCAGGAAGGCAACCGGCTGCATTATTTGGCTGACAGGGCGGGGGTGACAGGAAGCTTTATCCCGAAGCAACTGC
AGAAACTGGATCAGGCTTTCCCGCTGTTTGTAGAACAACTTGAAAATATGCTGCGCTCCGGCGAACTAAATCCACACCAG
CAACATCAGGTGACTATTCATCTTGCGGGTTTAACCTGCATAGCTGATACCCGTGGTAGCTGCGGCTACGTTTATATCGC
TATTTACCCCCAGGTTTCAGTTACCCAATAG