Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-MqsA
Location 1418143..1418878 Replicon chromosome
Accession NZ_CP022427
Organism Pantoea ananatis strain YJ76

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag B7764_RS06660 Protein ID WP_089517249.1
Coordinates 1418143..1418535 (+) Length 131 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag B7764_RS06665 Protein ID WP_089517250.1
Coordinates 1418525..1418878 (+) Length 118 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B7764_RS06645 1413439..1414611 - 1173 WP_089517247.1 FMNH2-dependent alkanesulfonate monooxygenase -
B7764_RS06650 1414890..1416776 + 1887 WP_026020924.1 aliphatic sulfonate ABC transporter substrate-binding protein -
B7764_RS06655 1416871..1417818 + 948 WP_089517248.1 sulfonate ABC transporter substrate-binding protein -
B7764_RS06660 1418143..1418535 + 393 WP_089517249.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
B7764_RS06665 1418525..1418878 + 354 WP_089517250.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
B7764_RS06680 1419424..1420602 - 1179 WP_089517251.1 tyrosine-type recombinase/integrase -
B7764_RS06685 1420560..1420766 - 207 WP_014605597.1 hypothetical protein -
B7764_RS06690 1420763..1422664 - 1902 WP_089517252.1 DNA cytosine methyltransferase -
B7764_RS06695 1422661..1423533 - 873 WP_089517253.1 phage N-6-adenine-methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1394096..1456033 61937


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(6-125)

Antitoxin

Antitoxin MqsA/HigA-2

(24-110)


Sequences

Toxin        


Download         Length: 131 a.a.        Molecular weight: 14959.25 Da        Isoelectric Point: 10.1482

>T79018 WP_089517249.1 NZ_CP022427:1418143-1418535 [Pantoea ananatis]
MGFTLYVHKRFDRVFKKTRLTDSVLCYAAGDVFTGVFEADLGGGVIKKRLALHQGKRGGARTVIFFRQGTNLVYYDGWVK
NLSRKYAKEIDEDQLDTYRDVARMFFRANSEVMSLLVRSGMVREVKCNEN

Download         Length: 393 bp

>T79018 NZ_CP022427:1418143-1418535 [Pantoea ananatis]
ATGGGTTTTACGCTTTATGTTCATAAACGTTTTGACAGAGTGTTTAAAAAAACGCGTCTGACAGACAGCGTCCTGTGTTA
CGCAGCAGGTGACGTTTTTACTGGCGTGTTTGAGGCTGACTTAGGCGGTGGCGTTATTAAAAAGCGTCTTGCTCTTCACC
AAGGCAAGCGTGGCGGCGCGCGAACGGTCATCTTCTTCAGACAAGGCACCAACCTGGTTTATTACGATGGATGGGTTAAA
AACTTGTCGAGGAAATACGCTAAAGAAATCGATGAAGATCAGCTGGATACCTACAGGGATGTGGCAAGAATGTTTTTCCG
TGCAAATAGTGAAGTGATGAGCCTGCTCGTCAGAAGCGGAATGGTCAGAGAGGTTAAATGTAATGAAAACTGA

Antitoxin


Download         Length: 118 a.a.        Molecular weight: 13123.17 Da        Isoelectric Point: 7.2076

>AT79018 WP_089517250.1 NZ_CP022427:1418525-1418878 [Pantoea ananatis]
MKTEPAELSELLEDAKAFHALGLATDEELESIAKRAKNRELRARIASVKPMTANEIKDVRMRWGMSQSLVALSFGMTVDS
VSKWERGEITPSPPVMRMLQLLRDNGPELFTSKHQGI

Download         Length: 354 bp

>AT79018 NZ_CP022427:1418525-1418878 [Pantoea ananatis]
ATGAAAACTGAACCCGCCGAATTGAGTGAACTACTTGAAGATGCGAAAGCGTTTCACGCGTTAGGACTGGCAACAGATGA
AGAATTGGAGTCCATAGCAAAGCGCGCAAAAAATCGTGAACTCCGTGCCCGTATTGCATCAGTAAAGCCCATGACAGCAA
ATGAAATCAAAGACGTGCGCATGCGTTGGGGAATGTCGCAATCGCTTGTGGCGCTCTCATTTGGCATGACGGTCGATAGC
GTATCGAAATGGGAGCGAGGTGAAATCACACCGAGCCCACCGGTGATGCGGATGCTACAACTCCTTCGCGATAACGGCCC
TGAACTCTTTACCTCTAAGCATCAAGGTATCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References