79013

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1684471..1686185 Replicon chromosome
Accession NZ_CP022426
Organism Aeromonas salmonicida subsp. pectinolytica 34mel

Toxin (Protein)


Gene name pmenT Uniprot ID T0QXU2
Locus tag Asalp_RS08085 Protein ID WP_021138005.1
Coordinates 1684471..1685124 (+) Length 218 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID T0R4W1
Locus tag Asalp_RS08090 Protein ID WP_021138004.1
Coordinates 1685121..1686185 (+) Length 355 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Asalp_RS08075 1681732..1682784 + 1053 WP_034523343.1 DUF1016 family protein -
Asalp_RS08080 1682788..1684215 + 1428 WP_021138006.1 restriction endonuclease subunit S -
Asalp_RS08085 1684471..1685124 + 654 WP_021138005.1 DUF4433 domain-containing protein Toxin
Asalp_RS08090 1685121..1686185 + 1065 WP_021138004.1 macro domain-containing protein Antitoxin
Asalp_RS08095 1686260..1689391 + 3132 WP_021138003.1 HsdR family type I site-specific deoxyribonuclease -
Asalp_RS08100 1689391..1690104 + 714 WP_021138002.1 M48 family metallopeptidase -
Asalp_RS08105 1690123..1691061 - 939 WP_021138001.1 restriction endonuclease -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(17-216)

Antitoxin

(18-131)


Sequences


Toxin        


Download         Length: 218 a.a.        Molecular weight: 25372.98 Da        Isoelectric Point: 6.8265

>T79013 WP_021138005.1 NZ_CP022426:1684471-1685124 [Aeromonas salmonicida subsp. pectinolytica 34mel]
MAYDYSQSLNPEKALIFRIVHRDNLEWILTHGLWAGNGQQQNPHWVHIGLPELIAKRARHPVPLAPYGVLNDYVPFYFTP
FSPMLSNIHSGRGVPQRENEEILILVSSLHRMAELGLPFVFTDSHAYYQWANFYVDLGDLGRIDWPLLQRRDFKRDAEDL
SKLERYQAEALIHQHCPIEALLGVVCYNEEIKNRVEQCMNRVGVARPVYVRDGWYFR

Download         Length: 654 bp

>T79013 NZ_CP022426:1684471-1685124 [Aeromonas salmonicida subsp. pectinolytica 34mel]
ATGGCCTATGACTATAGCCAGAGCCTGAATCCGGAGAAGGCGCTGATATTCCGGATCGTGCATCGGGATAACCTGGAATG
GATCCTGACCCATGGCCTGTGGGCGGGGAATGGTCAGCAGCAAAACCCGCACTGGGTGCATATCGGGCTGCCGGAGCTGA
TTGCCAAGCGCGCGCGCCATCCCGTGCCGCTGGCGCCTTACGGCGTGTTGAATGACTATGTGCCCTTCTACTTCACGCCG
TTTTCTCCCATGCTCAGCAATATTCACTCAGGGCGCGGTGTTCCCCAGCGTGAAAATGAAGAAATCCTGATCCTGGTTTC
CAGCCTGCATCGCATGGCTGAACTGGGGCTGCCGTTTGTGTTTACCGATAGCCATGCCTATTACCAGTGGGCCAATTTCT
ACGTCGACCTTGGCGATCTGGGGCGGATTGACTGGCCACTGTTGCAGCGCCGTGACTTCAAGCGTGATGCGGAAGATTTG
AGCAAGCTGGAGCGCTATCAGGCCGAGGCCTTGATCCATCAACATTGCCCCATCGAGGCGTTGCTGGGCGTGGTGTGTTA
CAACGAAGAGATAAAGAACCGCGTGGAACAATGCATGAATCGGGTCGGGGTCGCGCGCCCCGTCTATGTCCGTGATGGGT
GGTATTTCAGATGA

Antitoxin


Download         Length: 355 a.a.        Molecular weight: 39638.81 Da        Isoelectric Point: 6.9644

>AT79013 WP_021138004.1 NZ_CP022426:1685121-1686185 [Aeromonas salmonicida subsp. pectinolytica 34mel]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPANMRAYAEACKQGDVVTGKMFITQTGELLGPRWIVNFPTK
QHWRNPAQMAWIQDGLQDLRAWLQAQQVSSIAIPPLGAGNGGLPWPEVKQAIETALGDLDIDILLYEPSHQYQNVAKRGG
VAELTPARALIAELVRRYWFLGMECSLLEIQKLAWFLARVIGRNPLGDPLQLQFKAHRYGPYANNLTHLLNAMDGSYLQS
DKRIPDSKPFDVIWFNEAKKKELAVYLQTEAKAFLPILEQTTALIDGFESPYGMELLATVDWLIAEEGCAPTLSALREGL
HRWPAGTPWGERKARLFDDRSLQIALTRLQQGLV

Download         Length: 1065 bp

>AT79013 NZ_CP022426:1685121-1686185 [Aeromonas salmonicida subsp. pectinolytica 34mel]
ATGATTCGATATACAACAGGCAATCTGCTGGATGCTCCGGTGGAAGCGCTGGTGAATACCGTCAACACCGTCGGTGTCAT
GGGGAAGGGGATCGCCTTGATGTTCAAGGAGCGGTTCCCGGCCAATATGCGCGCCTATGCCGAGGCGTGCAAACAGGGTG
ACGTCGTCACCGGCAAGATGTTTATTACCCAGACGGGTGAGCTGCTAGGGCCGCGCTGGATCGTGAATTTCCCGACCAAA
CAGCACTGGCGCAATCCGGCACAGATGGCGTGGATCCAGGACGGTTTGCAGGATCTGCGGGCCTGGTTACAGGCGCAGCA
GGTCTCTTCGATTGCCATTCCGCCGCTGGGGGCTGGCAACGGTGGTCTGCCTTGGCCAGAGGTCAAACAGGCGATTGAAA
CGGCACTGGGCGATCTGGATATCGATATCCTGCTCTATGAGCCCAGTCACCAATACCAAAATGTGGCCAAGCGGGGCGGG
GTGGCGGAGCTGACTCCGGCTCGGGCCTTGATTGCTGAACTGGTACGTCGCTACTGGTTTTTAGGGATGGAGTGCAGCTT
GCTGGAGATCCAGAAGCTGGCCTGGTTTCTGGCGCGGGTTATTGGCCGCAACCCGCTGGGGGATCCGCTGCAGTTGCAGT
TTAAGGCCCATCGTTATGGCCCTTATGCCAACAATCTGACTCATCTGCTCAATGCGATGGACGGCAGTTATCTGCAGTCC
GACAAGCGCATTCCGGATAGCAAGCCGTTTGATGTCATCTGGTTTAATGAGGCCAAAAAAAAAGAGCTTGCCGTTTATCT
CCAGACCGAGGCCAAAGCATTTTTACCGATACTGGAGCAGACGACCGCGTTAATCGATGGTTTTGAGTCGCCCTATGGCA
TGGAGTTATTGGCCACGGTCGATTGGTTGATAGCCGAAGAGGGCTGTGCGCCGACGCTGAGCGCGCTGCGAGAGGGGTTG
CATCGCTGGCCAGCGGGAACCCCGTGGGGTGAGCGCAAGGCACGGCTGTTTGATGATCGCAGTCTGCAGATCGCCTTGAC
CCGTTTGCAGCAGGGATTGGTGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB T0QXU2


Antitoxin

Source ID Structure
AlphaFold DB T0R4W1

References