Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-RelB
Location 3010041..3010552 Replicon chromosome
Accession NZ_CP022423
Organism Vitreoscilla filiformis strain ATCC 15551

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag VITFI_RS14235 Protein ID WP_089417535.1
Coordinates 3010041..3010298 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag VITFI_RS14240 Protein ID WP_089417536.1
Coordinates 3010295..3010552 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VITFI_RS14210 3005200..3005769 - 570 WP_198301500.1 TetR/AcrR family transcriptional regulator -
VITFI_RS14215 3005989..3006528 + 540 WP_198301501.1 hypothetical protein -
VITFI_RS14220 3007132..3008106 - 975 WP_089417532.1 hypothetical protein -
VITFI_RS14225 3008283..3008945 + 663 WP_089417533.1 substrate-binding domain-containing protein -
VITFI_RS14230 3008999..3010027 + 1029 WP_089417534.1 amidohydrolase -
VITFI_RS14235 3010041..3010298 - 258 WP_089417535.1 Txe/YoeB family addiction module toxin Toxin
VITFI_RS14240 3010295..3010552 - 258 WP_089417536.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
VITFI_RS14245 3010699..3012939 - 2241 WP_089417537.1 NADP-dependent isocitrate dehydrogenase -
VITFI_RS14250 3013115..3014365 - 1251 WP_089417538.1 alanine racemase -
VITFI_RS14255 3014381..3014968 - 588 WP_089417539.1 crossover junction endodeoxyribonuclease RuvC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10266.63 Da        Isoelectric Point: 6.7240

>T79012 WP_089417535.1 NZ_CP022423:c3010298-3010041 [Vitreoscilla filiformis]
MILSFHPQAWEDYVYWQQTDKATLRRINLLIREIQRDPFEGIGKPEPLKFNFSGYWSRRIDDTHRIVYKVGDDEVIIAQL
RGHYD

Download         Length: 258 bp

>T79012 NZ_CP022423:c3010298-3010041 [Vitreoscilla filiformis]
ATGATCCTCTCCTTTCACCCGCAAGCGTGGGAAGACTATGTGTATTGGCAGCAGACCGATAAAGCCACCCTGCGCCGAAT
CAACTTGCTGATTCGGGAGATTCAGCGTGACCCGTTCGAGGGTATTGGGAAACCCGAACCGCTGAAATTCAACTTCAGCG
GTTATTGGTCACGCCGCATCGACGACACACATCGCATCGTTTACAAAGTGGGCGATGACGAGGTGATCATCGCCCAGTTG
CGAGGCCACTACGACTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9996.49 Da        Isoelectric Point: 6.7287

>AT79012 WP_089417536.1 NZ_CP022423:c3010552-3010295 [Vitreoscilla filiformis]
MRAITYTEARNNLASELDRVNNDYDVTIITRQKAEAGVLMSLKEYESLMETAHLLRHPKNAMRLMKAIEDIEARRHIVRR
ELIEE

Download         Length: 258 bp

>AT79012 NZ_CP022423:c3010552-3010295 [Vitreoscilla filiformis]
ATGCGTGCCATCACCTACACAGAAGCCCGCAACAACTTGGCCAGCGAGTTGGATCGGGTCAACAACGATTACGACGTGAC
CATCATCACCCGGCAAAAAGCCGAAGCCGGGGTGCTGATGTCACTCAAAGAATATGAGTCTCTGATGGAAACGGCGCATT
TGCTGCGTCATCCTAAAAACGCCATGCGTTTGATGAAGGCCATCGAAGACATTGAGGCGCGGCGCCACATCGTGCGCCGG
GAGTTGATCGAAGAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References