Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-PHD
Location 2975465..2976117 Replicon chromosome
Accession NZ_CP022423
Organism Vitreoscilla filiformis strain ATCC 15551

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag VITFI_RS14075 Protein ID WP_089417504.1
Coordinates 2975465..2975851 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag VITFI_RS14080 Protein ID WP_089417505.1
Coordinates 2975851..2976117 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VITFI_RS14060 2970770..2971705 + 936 WP_089418177.1 hydroxymethylglutaryl-CoA lyase -
VITFI_RS14065 2971839..2974790 + 2952 WP_089417502.1 PAS domain S-box protein -
VITFI_RS14070 2974787..2975437 + 651 WP_089417503.1 response regulator transcription factor -
VITFI_RS14075 2975465..2975851 - 387 WP_089417504.1 type II toxin-antitoxin system VapC family toxin Toxin
VITFI_RS14080 2975851..2976117 - 267 WP_089417505.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
VITFI_RS14085 2976259..2977764 + 1506 WP_089417506.1 toluene monooxygenase -
VITFI_RS14090 2977789..2978049 + 261 WP_089417507.1 toluene-4-monooxygenase system B family protein -
VITFI_RS14095 2978062..2978397 + 336 WP_089417508.1 Rieske 2Fe-2S domain-containing protein -
VITFI_RS14100 2978426..2978740 + 315 WP_089417509.1 MmoB/DmpM family protein -
VITFI_RS14105 2978757..2979758 + 1002 WP_089417510.1 aromatic/alkene monooxygenase hydroxylase subunit beta -
VITFI_RS14110 2979755..2980816 + 1062 WP_089417511.1 2Fe-2S iron-sulfur cluster binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

VapC-like Sll0205 protein, PIN domain

(4-126)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-44)


Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 14035.23 Da        Isoelectric Point: 6.6038

>T79011 WP_089417504.1 NZ_CP022423:c2975851-2975465 [Vitreoscilla filiformis]
MNLLLDTHVALWAITDSPRLPPQARALIAAPRTTVWVSVASLWEIAIKHSLGRGDMPVSGQEALQYFQASGYRLLAIEAE
HAVAVAGLPPHHQDPFDRLLVAQALTEPMRLMTHDAHVAAYSDTILKI

Download         Length: 387 bp

>T79011 NZ_CP022423:c2975851-2975465 [Vitreoscilla filiformis]
ATGAACCTGCTGCTCGACACCCACGTCGCCCTGTGGGCCATCACCGACAGCCCACGTCTGCCCCCGCAAGCGCGGGCGCT
GATTGCTGCGCCGCGCACCACCGTTTGGGTGAGTGTGGCCAGCCTGTGGGAAATCGCCATCAAACACAGCCTGGGGCGGG
GCGACATGCCGGTGTCCGGCCAAGAGGCGTTGCAGTACTTCCAGGCCTCGGGCTACCGCCTGCTGGCCATCGAGGCTGAA
CATGCGGTGGCGGTGGCCGGTTTGCCCCCTCACCATCAAGACCCGTTTGACCGCTTATTGGTCGCACAAGCCCTCACCGA
GCCCATGCGCTTGATGACCCATGACGCCCATGTGGCGGCGTACAGCGACACGATTCTCAAGATCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9343.75 Da        Isoelectric Point: 4.7527

>AT79011 WP_089417505.1 NZ_CP022423:c2976117-2975851 [Vitreoscilla filiformis]
MPAVNMLEAKTSLSRLVEAIELGREREIVIARNGRPVAKLVPLDVTAPGPRLGVAKGLFDVPDDIDAHNNDVARLFLGDM
NPTGEGAA

Download         Length: 267 bp

>AT79011 NZ_CP022423:c2976117-2975851 [Vitreoscilla filiformis]
ATGCCTGCCGTCAACATGCTGGAAGCCAAAACATCGCTGTCACGCTTGGTGGAAGCCATTGAGCTGGGGCGCGAACGCGA
GATCGTCATCGCCCGCAACGGTCGCCCCGTGGCCAAGCTGGTGCCGCTGGACGTCACCGCACCCGGCCCACGCCTGGGCG
TGGCCAAGGGTTTGTTTGACGTGCCCGATGACATCGACGCCCACAACAACGACGTAGCGCGCTTGTTCCTGGGCGACATG
AACCCAACGGGTGAAGGGGCTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References