Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2962373..2962962 Replicon chromosome
Accession NZ_CP022423
Organism Vitreoscilla filiformis strain ATCC 15551

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag VITFI_RS14020 Protein ID WP_089417495.1
Coordinates 2962373..2962762 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag VITFI_RS14025 Protein ID WP_089417496.1
Coordinates 2962759..2962962 (-) Length 68 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
VITFI_RS13995 2959834..2960568 - 735 WP_089417490.1 TetR/AcrR family transcriptional regulator -
VITFI_RS14000 2960583..2960960 - 378 WP_089417491.1 type II toxin-antitoxin system VapC family toxin -
VITFI_RS14005 2960968..2961219 - 252 WP_089417492.1 DUF2281 domain-containing protein -
VITFI_RS14010 2961433..2961900 - 468 WP_089417493.1 DUF2442 domain-containing protein -
VITFI_RS14015 2961897..2962325 - 429 WP_089417494.1 DUF4160 domain-containing protein -
VITFI_RS14020 2962373..2962762 - 390 WP_089417495.1 type II toxin-antitoxin system VapC family toxin Toxin
VITFI_RS14025 2962759..2962962 - 204 WP_089417496.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
VITFI_RS14030 2963041..2963601 + 561 WP_198301496.1 Uma2 family endonuclease -
VITFI_RS14035 2963720..2964892 + 1173 WP_089417498.1 isovaleryl-CoA dehydrogenase -
VITFI_RS14040 2964889..2966511 + 1623 WP_089417499.1 methylcrotonoyl-CoA carboxylase -
VITFI_RS14045 2966522..2967340 + 819 WP_089418176.1 enoyl-CoA hydratase/isomerase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-120)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 13794.15 Da        Isoelectric Point: 6.2096

>T79010 WP_089417495.1 NZ_CP022423:c2962762-2962373 [Vitreoscilla filiformis]
VTGVLIDTSVWVAHFRQCNAELVRLLALDGALMHPLVQAELACGTPPEPRARTLADLGLLPPVRQASLTEVLAFVERERL
YGLGCGVVELVLLASTLLTPGAVLWTLDKRLAALAGRFGVSYAPGDGWH

Download         Length: 390 bp

>T79010 NZ_CP022423:c2962762-2962373 [Vitreoscilla filiformis]
GTGACGGGGGTGCTCATCGACACCTCGGTGTGGGTGGCGCACTTTCGTCAGTGCAATGCCGAGCTGGTGCGCCTGCTGGC
GCTGGATGGCGCGCTGATGCACCCGCTGGTGCAAGCCGAGCTGGCCTGTGGCACCCCACCTGAACCGCGTGCGCGCACGC
TGGCTGATTTGGGGCTGCTGCCCCCGGTGCGCCAAGCCAGCCTGACCGAAGTCCTGGCTTTTGTGGAGCGCGAGCGGCTC
TACGGCCTGGGTTGTGGTGTGGTGGAGTTGGTGCTGCTGGCCTCGACGCTGCTGACGCCGGGGGCCGTTTTATGGACGCT
GGACAAGCGCTTGGCTGCGTTGGCCGGGCGGTTTGGCGTGAGCTACGCGCCGGGAGACGGGTGGCACTGA

Antitoxin


Download         Length: 68 a.a.        Molecular weight: 7474.62 Da        Isoelectric Point: 6.2838

>AT79010 WP_089417496.1 NZ_CP022423:c2962962-2962759 [Vitreoscilla filiformis]
MRTTVTIEDALYERALEMADPGMDKADLFREAIKTFVRVQAAKRLAALGGTQPNMAEVPRQRQEPVA

Download         Length: 204 bp

>AT79010 NZ_CP022423:c2962962-2962759 [Vitreoscilla filiformis]
ATGCGAACCACCGTGACGATTGAAGATGCCCTGTATGAACGCGCCCTGGAAATGGCCGACCCGGGCATGGACAAGGCGGA
TTTGTTCCGCGAGGCCATCAAAACCTTTGTGCGGGTGCAGGCTGCCAAACGGCTGGCTGCGCTGGGGGGCACACAGCCGA
ACATGGCGGAAGTACCACGCCAGCGCCAGGAGCCGGTGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References