Detailed information of TA system TA079009

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbE-relB/ParE-YafN
• Location: 2126413..2127007
• Replicon: chromosome
• Accession: NZ_CP022423
• Organism: Vitreoscilla filiformis strain ATCC 15551

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: VITFI_RS10185
• Protein ID: WP_089416863.1
• Coordinates: 2126413..2126766 (-)
• Length: 118 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: VITFI_RS10190
• Protein ID: WP_198301414.1
• Coordinates: 2126753..2127007 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
VITFI_RS10165	2121950..2123128	+	1179	WP_089416859.1	acetyl-CoA C-acetyltransferase	-
VITFI_RS10170	2123256..2123993	+	738	WP_089416860.1	acetoacetyl-CoA reductase	-
VITFI_RS10180	2124705..2125646	-	942	WP_089416862.1	AAA family ATPase	-
VITFI_RS10185	2126413..2126766	-	354	WP_089416863.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
VITFI_RS10190	2126753..2127007	-	255	WP_198301414.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
VITFI_RS10195	2127560..2127979	-	420	WP_089416864.1	hypothetical protein	-
VITFI_RS10200	2128083..2128367	-	285	WP_089416865.1	hypothetical protein	-
VITFI_RS10205	2128364..2128708	-	345	WP_157725639.1	hypothetical protein	-
VITFI_RS10210	2128720..2128938	-	219	WP_089416867.1	DUF2788 domain-containing protein	-
VITFI_RS10215	2128939..2129112	-	174	WP_198301415.1	hypothetical protein	-
VITFI_RS10220	2129264..2131924	-	2661	WP_089416868.1	[protein-PII] uridylyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (13-90)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (11-78)

Sequences

Toxin

Protein

• Length: 118 a.a.
• Molecular weight: 13252.55 Da
• Isoelectric Point: 10.1021

>T79009 WP_089416863.1 NZ_CP022423:c2126766-2126413 [Vitreoscilla filiformis]
MTTSKKHTYKLFFLPQALTEWKALDGSVKENIKKLLAKRLDNPHTPVGELHGELKGCYKIKLNKQGVRLVYAVEDDKLIV
MVMSVDKREDSIVYKSAVTRMTEKAATLAKITKDESS

Nucleotide

• Length: 354 bp

>T79009 NZ_CP022423:c2126766-2126413 [Vitreoscilla filiformis]
TTGACGACCTCTAAAAAGCACACATATAAACTTTTCTTTTTACCACAAGCACTAACGGAGTGGAAAGCGCTTGATGGTTC
AGTTAAAGAAAACATAAAAAAACTACTCGCAAAAAGGCTCGATAATCCACACACTCCCGTTGGCGAGTTACACGGAGAGT
TGAAAGGTTGCTACAAGATAAAGCTCAACAAACAAGGAGTTCGACTTGTTTATGCAGTTGAAGACGATAAATTGATCGTC
ATGGTAATGTCGGTAGACAAACGAGAAGATAGTATCGTTTACAAATCTGCCGTGACACGAATGACTGAAAAAGCCGCAAC
ACTTGCAAAAATCACGAAAGATGAGTCATCATAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9465.04 Da
• Isoelectric Point: 4.7672

>AT79009 WP_198301414.1 NZ_CP022423:c2127007-2126753 [Vitreoscilla filiformis]
MMQLILADVAVSMSEFKKNPAAILREANNRPVAVLNHNKAAFYMIKPELFEAIMEEISDQDLYKKVLARLADKSSAIEVN
LDDL

Nucleotide

• Length: 255 bp

>AT79009 NZ_CP022423:c2127007-2126753 [Vitreoscilla filiformis]
ATGATGCAACTAATCCTAGCAGACGTAGCGGTCAGCATGTCTGAGTTCAAAAAGAACCCGGCAGCAATTCTGCGAGAAGC
CAATAACCGACCGGTAGCAGTTTTAAATCACAATAAAGCTGCTTTTTACATGATTAAACCAGAGCTTTTCGAGGCAATCA
TGGAAGAAATTTCCGATCAAGATTTATATAAAAAAGTACTAGCGCGACTTGCAGATAAATCGAGCGCTATAGAGGTTAAT
CTTGACGACCTCTAA