Detailed information of TA system TA079006

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 84443..85455
• Replicon: chromosome
• Accession: NZ_CP022423
• Organism: Vitreoscilla filiformis strain ATCC 15551

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: VITFI_RS00400
• Protein ID: WP_089415318.1
• Coordinates: 84443..85018 (-)
• Length: 192 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: VITFI_RS00405
• Protein ID: WP_089417888.1
• Coordinates: 85015..85455 (-)
• Length: 147 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
VITFI_RS00385	79624..81003	+	1380	WP_198301689.1	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	-
VITFI_RS00390	81012..81341	+	330	WP_089415316.1	hypothetical protein	-
VITFI_RS00395	81367..84429	+	3063	WP_089415317.1	SUMF1/EgtB/PvdO family nonheme iron enzyme	-
VITFI_RS00400	84443..85018	-	576	WP_089415318.1	PIN domain-containing protein	Toxin
VITFI_RS00405	85015..85455	-	441	WP_089417888.1	helix-turn-helix domain-containing protein	Antitoxin

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-115)

Antitoxin

• Helix-turn-helix domain, group 17 (75-123)

Sequences

Toxin

Protein

• Length: 192 a.a.
• Molecular weight: 21599.01 Da
• Isoelectric Point: 6.2351

>T79006 WP_089415318.1 NZ_CP022423:c85018-84443 [Vitreoscilla filiformis]
VMPSPFTVVYDACVLYPAPLRDFLMWLGLSGRFRARWTAQIHEEWKRNLLANRPDLTWEQVNRTSACMDWAIPDALVTGY
EPLMAGLVLPDVDDRHVLAAAIRCQASVIVTFNRKDFPAQVLAPFGIEAQHPDEFIDNLFDLDPAAVVTAAQKQRQKLRT
PPIEVERYLDTLLKQGLVQTVKGLGAFRQVL

Nucleotide

• Length: 576 bp

>T79006 NZ_CP022423:c85018-84443 [Vitreoscilla filiformis]
GTGATGCCTTCACCCTTCACGGTTGTTTACGACGCCTGTGTGTTGTACCCCGCTCCTCTGCGGGACTTTCTCATGTGGCT
GGGCCTCTCAGGGCGTTTTCGGGCTCGCTGGACTGCGCAAATTCATGAGGAATGGAAGCGCAATCTGTTGGCCAACCGGC
CCGACCTGACCTGGGAGCAGGTGAATCGCACGTCAGCATGCATGGATTGGGCGATTCCGGATGCACTGGTAACGGGCTAT
GAGCCGTTGATGGCGGGTTTGGTCTTGCCGGATGTAGACGATCGGCATGTGTTGGCTGCGGCCATCCGCTGTCAGGCCAG
TGTGATCGTGACCTTCAACCGCAAGGACTTCCCGGCCCAGGTGCTGGCCCCGTTCGGTATCGAAGCCCAGCACCCGGACG
AATTCATCGACAACCTGTTTGACCTCGATCCGGCTGCCGTGGTCACTGCCGCTCAGAAGCAGCGCCAGAAACTCCGAACG
CCACCGATCGAGGTGGAGCGTTACCTGGACACCCTGCTCAAGCAAGGACTGGTACAAACGGTGAAGGGCTTGGGGGCATT
TCGGCAGGTGTTGTAG

Antitoxin

Protein

• Length: 147 a.a.
• Molecular weight: 16465.77 Da
• Isoelectric Point: 4.7760

>AT79006 WP_089417888.1 NZ_CP022423:c85455-85015 [Vitreoscilla filiformis]
MLPVEREVLAAAEGQRTLAAYLSTQFETQRIQIFDEKDEAHRVELPVSALRLLVEILAELAEGNAVKVVPIHAELTTQEA
ADLLNVSRPYLVKLLEDGALPFHKTGKHRRVRFADVMRYKAEREQESADAMAELAQQAQELQLGYE

Nucleotide

• Length: 441 bp

>AT79006 NZ_CP022423:c85455-85015 [Vitreoscilla filiformis]
ATGCTGCCCGTCGAGCGCGAAGTGCTGGCTGCGGCGGAAGGCCAGCGCACGCTGGCGGCTTATCTTTCCACCCAGTTCGA
GACGCAACGTATCCAGATCTTCGACGAGAAGGATGAAGCGCATCGGGTGGAGCTGCCCGTCTCCGCCCTGAGGTTGCTGG
TGGAAATCTTGGCCGAGCTGGCTGAGGGCAACGCGGTGAAAGTGGTACCCATCCACGCAGAACTGACCACGCAGGAAGCG
GCGGACTTGCTGAACGTCTCCCGCCCTTATCTGGTGAAGCTGCTGGAGGATGGCGCTTTGCCGTTCCACAAAACGGGCAA
GCACCGGCGCGTACGGTTCGCGGATGTGATGCGCTACAAGGCCGAGCGCGAACAAGAAAGCGCCGATGCCATGGCCGAAC
TGGCACAACAGGCTCAGGAACTGCAACTGGGTTACGAGTGA