Detailed information of TA system TA079004

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-RelB
• Location: 197277..197838
• Replicon: plasmid pSMR1-4
• Accession: NZ_CP022419
• Organism: Sulfitobacter pseudonitzschiae strain SMR1

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: SULPSESMR1_RS23140
• Protein ID: WP_089423419.1
• Coordinates: 197277..197552 (-)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: SULPSESMR1_RS23145
• Protein ID: WP_089423420.1
• Coordinates: 197545..197838 (-)
• Length: 98 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SULPSESMR1_RS23130	192594..192800	-	207	WP_198362926.1	hypothetical protein	-
SULPSESMR1_RS23135	192907..197163	-	4257	WP_089423418.1	strawberry notch family protein	-
SULPSESMR1_RS23140	197277..197552	-	276	WP_089423419.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
SULPSESMR1_RS23145	197545..197838	-	294	WP_089423420.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
SULPSESMR1_RS23150	197907..198563	-	657	WP_089423421.1	hypothetical protein	-
SULPSESMR1_RS23155	198563..199156	-	594	WP_089423422.1	regulator	-
SULPSESMR1_RS23160	199264..201246	-	1983	WP_089423423.1	ParB/RepB/Spo0J family partition protein	-
SULPSESMR1_RS23165	201711..202742	-	1032	WP_047997789.1	IS110 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..209222	209222

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (5-54)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10285.74 Da
• Isoelectric Point: 4.4275

>T79004 WP_089423419.1 NZ_CP022419:c197552-197277 [Sulfitobacter pseudonitzschiae]
VPDLEWKATAIADLLAIIDYISDDNPDAAQALKDEIEAKTSRLPEHPQMYRVGRVDGTREMVVRPNYIVIYADDPSAIMI
LRVLHAAQQWP

Nucleotide

• Length: 276 bp

>T79004 NZ_CP022419:c197552-197277 [Sulfitobacter pseudonitzschiae]
GTGCCTGATCTCGAATGGAAGGCCACGGCCATCGCTGATCTGCTGGCGATTATCGACTACATCTCTGACGACAATCCAGA
TGCGGCCCAAGCTCTCAAGGACGAAATCGAGGCCAAGACGTCACGATTGCCAGAGCACCCCCAGATGTACCGCGTGGGAC
GTGTTGACGGCACCCGTGAAATGGTCGTGCGTCCAAATTACATCGTGATTTATGCTGACGACCCAAGTGCCATAATGATC
TTGCGGGTGCTGCACGCAGCTCAGCAGTGGCCGTAG

Antitoxin

Protein

• Length: 98 a.a.
• Molecular weight: 10393.80 Da
• Isoelectric Point: 5.6448

>AT79004 WP_089423420.1 NZ_CP022419:c197838-197545 [Sulfitobacter pseudonitzschiae]
MPAQTSMIHVRVDDQLKAQASDALSGVGLTLSDAVRILLTRVAAEGGLPAGLTADPDAYDAWFRSKVQEALDDPKPTTPH
AQVMQDAQALIDKKRRA

Nucleotide

• Length: 294 bp

>AT79004 NZ_CP022419:c197838-197545 [Sulfitobacter pseudonitzschiae]
ATGCCCGCTCAAACATCCATGATCCATGTCCGTGTTGACGATCAGCTAAAAGCGCAGGCCTCGGATGCGCTCTCGGGTGT
CGGCCTGACGCTCTCGGATGCCGTACGCATCCTCTTGACGCGCGTGGCCGCAGAGGGCGGATTGCCAGCGGGACTGACCG
CGGATCCAGACGCTTATGACGCATGGTTCCGTTCCAAAGTGCAGGAAGCATTGGACGACCCAAAGCCGACAACACCGCAT
GCTCAGGTAATGCAAGACGCTCAGGCACTGATTGATAAGAAGCGCCGTGCCTGA