Detailed information of TA system TA078997

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 2399954..2400419
• Replicon: chromosome
• Accession: NZ_CP022411
• Organism: Pseudomonas sp. RU47

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CCX46_RS10965
• Protein ID: WP_127926662.1
• Coordinates: 2399954..2400223 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: CCX46_RS10970
• Protein ID: WP_083368637.1
• Coordinates: 2400213..2400419 (-)
• Length: 69 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CCX46_RS10945	2395063..2395923	+	861	WP_038364894.1	curli production assembly/transporter CsgG	-
CCX46_RS10950	2397185..2397658	+	474	WP_127926660.1	hypothetical protein	-
CCX46_RS10955	2399337..2399708	+	372	WP_127926661.1	hypothetical protein	-
CCX46_RS10965	2399954..2400223	-	270	WP_127926662.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CCX46_RS10970	2400213..2400419	-	207	WP_083368637.1	antitoxin	Antitoxin
CCX46_RS10975	2400721..2402172	-	1452	WP_127926663.1	curlin	-
CCX46_RS10980	2402200..2402664	-	465	WP_127926664.1	curlin	-
CCX46_RS10985	2402738..2404966	-	2229	WP_127926665.1	cadherin-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10249.81 Da
• Isoelectric Point: 6.8777

>T78997 WP_127926662.1 NZ_CP022411:c2400223-2399954 [Pseudomonas sp. RU47]
MQVEWQPEARAELLKILDYISDRNLVAADRLSQAIEGATVTLAQHPHVYRMGRAPGTREMVVHPNYLIIYQVVDRINILS
VLHARQEYP

Nucleotide

• Length: 270 bp

>T78997 NZ_CP022411:c2400223-2399954 [Pseudomonas sp. RU47]
ATGCAGGTTGAGTGGCAGCCCGAAGCTCGGGCTGAACTCCTGAAAATCCTTGATTACATCAGTGACAGGAACTTAGTAGC
GGCTGACAGACTTTCCCAAGCTATCGAAGGCGCTACGGTTACCCTTGCTCAACATCCACACGTCTATCGAATGGGTCGAG
CACCCGGTACTCGCGAGATGGTCGTACACCCCAATTACCTGATCATTTATCAGGTGGTGGATCGGATAAATATTCTGAGC
GTTTTGCATGCGCGTCAGGAATATCCATAA

Antitoxin

Protein

• Length: 69 a.a.
• Molecular weight: 7609.72 Da
• Isoelectric Point: 4.2985

>AT78997 WP_083368637.1 NZ_CP022411:c2400419-2400213 [Pseudomonas sp. RU47]
MIDPSLIDPLCPVVSDLDPEEQAASYDRWLIAKVQASMSDTRPSIPNDQVMAEMRALMEAKRKKYDAG

Nucleotide

• Length: 207 bp

>AT78997 NZ_CP022411:c2400419-2400213 [Pseudomonas sp. RU47]
ATGATCGACCCGTCTTTAATCGACCCACTGTGCCCAGTTGTTTCAGATCTTGACCCCGAAGAGCAGGCCGCCAGCTATGA
CCGTTGGTTAATCGCCAAAGTGCAGGCTTCGATGAGTGATACAAGACCGAGCATTCCAAATGATCAGGTTATGGCTGAGA
TGCGTGCCCTGATGGAAGCAAAGCGTAAAAAATACGATGCAGGTTGA