Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 634840..635108 Replicon chromosome
Accession NZ_CP022407
Organism Escherichia coli O121:H19 strain 16-9255

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 634967..635070 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 634840..635108 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CGC46_RS03230 631393..632055 - 663 WP_000944246.1 exodeoxyribonuclease X -
CGC46_RS03235 632079..632735 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CGC46_RS03240 632837..633067 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CGC46_RS03245 633206..633580 + 375 WP_000168739.1 CopC domain-containing protein YobA -
CGC46_RS03250 633584..634456 + 873 WP_000879277.1 copper homeostasis membrane protein CopD -
CGC46_RS03255 634469..634810 + 342 WP_000976478.1 YebY family protein -
- 634840..635108 - 269 - - Antitoxin
- 634967..635070 + 104 - - Toxin
CGC46_RS03260 635205..635861 + 657 WP_000812712.1 protein-serine/threonine phosphatase -
CGC46_RS03265 635862..636053 - 192 WP_001296140.1 YebW family protein -
CGC46_RS03270 636158..636394 - 237 WP_001295499.1 DUF1480 family protein -
CGC46_RS03275 636512..637951 - 1440 WP_001343151.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T78963 NZ_CP022407:634967-635070 [Escherichia coli O121:H19]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT78963 NZ_CP022407:c635108-634840 [Escherichia coli O121:H19]
AAAGTCAGCGAAGGGAATGTTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References