Detailed information of TA system TA078928

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): slvAT/RES-TIGR02293
• Location: 51725..52638
• Replicon: plasmid unnamed1
• Accession: NZ_CP022370
• Organism: Bosea sp. AS-1

Toxin (Protein)

• Gene name: slvT
• Uniprot ID: -
• Locus tag: CE453_RS00295
• Protein ID: WP_089172791.1
• Coordinates: 52108..52638 (+)
• Length: 177 a.a.

Antitoxin (Protein)

• Gene name: slvA
• Uniprot ID: -
• Locus tag: CE453_RS00290
• Protein ID: WP_089172790.1
• Coordinates: 51725..52111 (+)
• Length: 129 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CE453_RS00265	47095..47520	+	426	WP_089172787.1	arsenate reductase (glutaredoxin)	-
CE453_RS00270	47528..48580	+	1053	WP_089172902.1	ACR3 family arsenite efflux transporter	-
CE453_RS00275	48639..48956	+	318	WP_089172788.1	metalloregulator ArsR/SmtB family transcription factor	-
CE453_RS00280	49013..50418	+	1406	Protein_53	NAD(P)-binding domain-containing protein	-
CE453_RS00285	50400..51590	+	1191	WP_089172789.1	MFS transporter	-
CE453_RS00290	51725..52111	+	387	WP_089172790.1	DUF2384 domain-containing protein	Antitoxin
CE453_RS00295	52108..52638	+	531	WP_089172791.1	RES family NAD+ phosphorylase	Toxin
CE453_RS00300	52833..53636	-	804	WP_089172792.1	undecaprenyl-diphosphate phosphatase	-
CE453_RS00305	53636..54058	-	423	WP_198302109.1	ArsR family transcriptional regulator	-
CE453_RS00310	54587..55441	-	855	Protein_59	murein L,D-transpeptidase	-
CE453_RS28875	55967..56179	-	213	WP_191124874.1	hypothetical protein	-
CE453_RS00325	56222..56618	+	397	Protein_61	helix-turn-helix domain-containing protein	-
CE453_RS00330	56709..57494	+	786	WP_089172794.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..189990	189990

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (12-168)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 177 a.a.
• Molecular weight: 19097.64 Da
• Isoelectric Point: 6.7176

>T78928 WP_089172791.1 NZ_CP022370:52108-52638 [Bosea sp. AS-1]
MKLVRLGPDEVFHRYLTPKWAFVPTSGAGAAMVGGRFNRIGVEALYLSRAPQTALEEYRQGSSLTRPATLAAYMIDLQQV
VDFSAGYDPNVWAAAWASWDCDWRKIYNILGKIPPSWPLADAAISAGYGGILFPSLRHPGGTNLVVFGANLSASDSVAVH
DPDESLPKDQSSWSKA

Nucleotide

• Length: 531 bp

>T78928 NZ_CP022370:52108-52638 [Bosea sp. AS-1]
ATGAAGCTTGTCCGGCTTGGACCGGACGAGGTCTTCCATCGCTATCTGACGCCAAAGTGGGCATTCGTGCCGACCAGCGG
AGCTGGCGCAGCTATGGTCGGCGGCCGCTTCAATCGAATTGGTGTCGAGGCGCTTTATCTTTCGCGCGCGCCGCAGACTG
CTCTGGAGGAATATCGCCAGGGTTCGTCATTGACCCGACCCGCGACGCTTGCTGCATACATGATCGACCTTCAACAAGTC
GTCGATTTCTCCGCCGGCTATGATCCGAATGTCTGGGCAGCGGCCTGGGCGTCATGGGACTGTGACTGGCGGAAAATCTA
CAACATCCTAGGCAAGATCCCGCCATCCTGGCCGCTTGCAGATGCTGCGATTTCCGCGGGCTATGGGGGGATCTTGTTCC
CGTCACTCCGGCATCCGGGTGGAACCAATCTGGTCGTTTTCGGCGCAAACCTGAGCGCTTCTGATTCCGTCGCAGTCCAC
GATCCAGACGAGAGCCTTCCCAAAGATCAATCCTCCTGGTCCAAGGCCTGA

Antitoxin

Protein

• Length: 129 a.a.
• Molecular weight: 14056.17 Da
• Isoelectric Point: 9.4193

>AT78928 WP_089172790.1 NZ_CP022370:51725-52111 [Bosea sp. AS-1]
MAHAERLGPAIVSGFMQKLQEPKTPYISPGRFSKVLGIQVSSLAKMTGVHRNTLRKPSSERLQGRFREMAKVITAAAELA
GDLDKAIYWFMNEPISDYDHKTAAELVAEGHSEAVLRYLQALEIGASG

Nucleotide

• Length: 387 bp

>AT78928 NZ_CP022370:51725-52111 [Bosea sp. AS-1]
ATGGCACATGCTGAGAGACTTGGTCCGGCGATTGTGTCGGGCTTTATGCAGAAGCTGCAGGAACCGAAGACCCCCTATAT
TTCTCCAGGGCGCTTCTCGAAGGTGCTGGGCATCCAGGTTTCCAGCCTGGCAAAAATGACAGGCGTTCATCGGAACACGC
TTCGCAAGCCAAGCTCGGAGAGGCTTCAAGGTCGGTTTCGCGAGATGGCAAAGGTCATAACGGCCGCAGCTGAACTCGCA
GGCGATCTCGACAAGGCGATTTATTGGTTCATGAATGAACCGATTTCCGACTACGATCATAAAACGGCTGCGGAACTGGT
CGCCGAAGGTCATAGCGAAGCTGTATTGAGGTATCTGCAAGCCCTCGAAATCGGAGCGAGCGGATGA