Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH_26
Location 511167..511782 Replicon plasmid TSH58_p05
Accession NZ_CP022369
Organism Azospirillum sp. TSH58

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag TSH58p_RS32590 Protein ID WP_109067838.1
Coordinates 511167..511421 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag TSH58p_RS32595 Protein ID WP_109067839.1
Coordinates 511414..511782 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
TSH58p_RS32570 506319..507218 - 900 WP_109067835.1 4-hydroxy-tetrahydrodipicolinate synthase -
TSH58p_RS32575 507604..508734 - 1131 WP_109067961.1 alpha-hydroxy-acid oxidizing protein -
TSH58p_RS32580 508991..510427 + 1437 WP_109067836.1 FAD-binding oxidoreductase -
TSH58p_RS32585 510424..511116 + 693 WP_109067837.1 XRE family transcriptional regulator -
TSH58p_RS32590 511167..511421 + 255 WP_109067838.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
TSH58p_RS32595 511414..511782 + 369 WP_109067839.1 helix-turn-helix transcriptional regulator Antitoxin
TSH58p_RS32600 511775..512662 - 888 WP_109067840.1 TonB family protein -
TSH58p_RS32605 512709..514805 - 2097 WP_109067841.1 TonB-dependent receptor -
TSH58p_RS32610 514854..516287 - 1434 WP_109067842.1 thiol oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - pvdE / adeG 1..568757 568757


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-80)

Antitoxin

Cro/C1-type helix-turn-helix domain

(67-121)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9499.12 Da        Isoelectric Point: 10.5794

>T78927 WP_109067838.1 NZ_CP022369:511167-511421 [Azospirillum sp. TSH58]
MHTIRYTAAALKTLRRMPRNTADLIRLKLQEVAADPANGRNVKKLKGRDGYRLHVGDWRIVYDLESGVLVLIVIEVGPRG
GIYE

Download         Length: 255 bp

>T78927 NZ_CP022369:511167-511421 [Azospirillum sp. TSH58]
ATGCACACGATCCGCTATACCGCGGCGGCCCTGAAGACGCTTCGCCGAATGCCGCGCAACACGGCGGACCTGATCCGCCT
GAAGCTGCAGGAGGTGGCCGCCGACCCGGCGAACGGGCGGAACGTAAAGAAGCTGAAGGGCCGCGACGGCTACCGGCTCC
ACGTCGGCGACTGGCGGATCGTTTATGACCTCGAATCCGGCGTGCTGGTGCTGATCGTCATCGAAGTCGGCCCGAGAGGA
GGCATCTATGAGTGA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13206.86 Da        Isoelectric Point: 4.4493

>AT78927 WP_109067839.1 NZ_CP022369:511414-511782 [Azospirillum sp. TSH58]
MSDPAQIIRDGNGNPVFAVLPIAEYERLLQAADEAIATRAFDVYKATQPETFPDDVAERLLSGEHPVKVFRDHRGMTQAQ
LAEAAGLKQAYVSQIEAGTRGGSVDVLKRIADALQVDLADLT

Download         Length: 369 bp

>AT78927 NZ_CP022369:511414-511782 [Azospirillum sp. TSH58]
ATGAGTGATCCCGCGCAGATCATCCGGGATGGCAACGGCAATCCGGTCTTCGCGGTTCTTCCCATCGCCGAGTATGAACG
GTTGCTGCAGGCCGCCGACGAAGCAATCGCGACCCGCGCCTTCGACGTCTACAAGGCAACCCAGCCGGAGACATTCCCCG
ATGACGTGGCTGAGCGGCTGCTGAGCGGCGAACATCCGGTGAAGGTCTTCCGCGACCATCGCGGCATGACACAGGCCCAA
CTCGCGGAAGCCGCCGGGCTCAAGCAAGCCTATGTCTCGCAGATCGAGGCCGGCACGCGTGGTGGTTCGGTGGACGTGCT
CAAGCGGATCGCCGACGCTCTCCAGGTGGACCTCGCCGACCTCACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References