78917

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 335542..336884 Replicon chromosome
Accession NZ_CP022353
Organism Vibrio sp. 2521-89

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag CEQ48_RS07100 Protein ID WP_176224104.1
Coordinates 335949..336884 (+) Length 312 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag CEQ48_RS07095 Protein ID WP_085602509.1
Coordinates 335542..335946 (+) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEQ48_RS07085 331068..334298 + 3231 WP_001126441.1 carbamoyl-phosphate synthase large subunit -
CEQ48_RS07090 334388..334870 - 483 WP_089070754.1 hypothetical protein -
CEQ48_RS07095 335542..335946 + 405 WP_085602509.1 S-adenosylhomocysteine hydrolase Antitoxin
CEQ48_RS07100 335949..336884 + 936 WP_176224104.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CEQ48_RS07105 337305..338090 + 786 WP_089070755.1 TSUP family transporter -
CEQ48_RS07110 338020..338880 - 861 WP_089070756.1 LysR family transcriptional regulator -
CEQ48_RS07115 339031..339651 - 621 WP_000381501.1 TRIC cation channel family protein -
CEQ48_RS07120 339734..340565 - 832 Protein_313 vitamin B12 ABC transporter substrate-binding protein BtuF -
CEQ48_RS07125 340566..341519 - 954 WP_089070757.1 cobalamin biosynthesis family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(37-300)

Antitoxin

Protein of unknown function DUF6088

(8-130)


Sequences

Toxin        


Download         Length: 312 a.a.        Molecular weight: 35764.86 Da        Isoelectric Point: 5.1687

>T78917 WP_176224104.1 NZ_CP022353:335949-336884 [Vibrio sp. 2521-89]
IPKLKKQFLEVSDALELGNPSITEKDYWVVSLLAMLESVESKHHQLVFSGGTALAKSNIKILRMSEDVDIKLIPTQEFLD
KGTGAKIKARKALVEQVIARLIDHTYLNYSDKTVRDSYRYVEIEIEYPQQYHQAPCLRPYIKLEFIETIELQGVEPRSIS
SLVAQSYNQPAEVSAMSCISIDSTLVEKVLSMLRRTMSVKRDPQRKDDETLVRHIYDVHCISAEHTINMGVLKPMFDTVL
EEDKTRYGNQHPEFVDDPRNELKLGLEELETNEEFRKRFDAFVAPMVYNTEPHDFDTCFASFKAISEQLIS

Download         Length: 936 bp

>T78917 NZ_CP022353:335949-336884 [Vibrio sp. 2521-89]
ATACCAAAACTAAAAAAACAATTTCTTGAAGTATCTGATGCCCTCGAGTTAGGTAACCCGTCGATCACGGAAAAGGACTA
TTGGGTGGTGTCTCTGCTTGCCATGTTGGAAAGCGTGGAAAGTAAGCACCACCAGCTTGTTTTTTCAGGTGGAACAGCTT
TGGCCAAGTCCAATATTAAGATTCTGCGAATGTCTGAAGACGTCGACATCAAATTGATTCCAACTCAGGAATTTCTCGAT
AAGGGCACAGGTGCGAAGATAAAAGCTCGCAAAGCGTTAGTCGAACAAGTCATAGCGAGGTTAATTGACCACACTTATCT
GAATTATAGTGATAAAACGGTACGTGATAGTTATCGCTATGTTGAAATCGAAATAGAGTACCCACAACAATACCATCAAG
CACCGTGTCTAAGACCTTATATCAAACTGGAATTTATCGAGACAATTGAACTTCAGGGCGTTGAGCCTCGCTCTATTTCA
TCGCTGGTCGCGCAGAGCTACAATCAACCTGCCGAAGTAAGCGCAATGTCGTGTATATCCATTGACTCGACGTTGGTTGA
AAAAGTGCTTTCCATGTTGCGTCGCACCATGTCAGTTAAGCGTGATCCACAGCGTAAGGATGACGAAACATTGGTTCGTC
ATATCTACGATGTTCACTGTATTAGCGCCGAGCATACGATTAATATGGGCGTATTAAAGCCGATGTTTGATACCGTTTTG
GAAGAGGACAAGACGCGATATGGCAATCAACATCCGGAGTTTGTCGATGATCCGCGCAATGAGTTAAAACTAGGATTAGA
AGAGCTAGAAACCAACGAGGAGTTTCGTAAACGTTTTGACGCGTTTGTTGCCCCAATGGTTTACAACACAGAACCACATG
ACTTTGATACCTGTTTTGCCTCATTCAAAGCTATTTCAGAGCAGCTTATTAGCTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15470.01 Da        Isoelectric Point: 10.8398

>AT78917 WP_085602509.1 NZ_CP022353:335542-335946 [Vibrio sp. 2521-89]
MTATDLIYQKIKRSRRYVFERKDFDNYASYDQIGRVLKKLVDKGVLMKIGYGLYTKSTINSLTNKPMPTNPGGTDAIMRE
ILKMRGVDFELDAMSLKSINGQTTQIPASIRYKWNSKHFNRSLKVGNRVLSKRQ

Download         Length: 405 bp

>AT78917 NZ_CP022353:335542-335946 [Vibrio sp. 2521-89]
ATGACAGCAACTGATCTTATTTATCAAAAGATAAAGCGCTCTCGACGCTATGTGTTCGAACGTAAAGACTTCGACAACTA
TGCTAGCTATGACCAGATTGGTCGTGTGTTGAAAAAACTAGTGGATAAAGGTGTACTGATGAAAATCGGGTATGGCTTAT
ACACCAAGTCAACAATCAACAGCCTGACTAATAAACCGATGCCTACGAATCCCGGTGGTACTGACGCAATCATGCGTGAA
ATCCTAAAAATGCGCGGGGTAGACTTTGAGCTGGATGCTATGTCATTGAAGAGTATCAATGGACAGACCACTCAAATACC
AGCGTCCATCAGGTACAAGTGGAACTCTAAGCATTTCAATCGCAGCCTTAAGGTTGGTAACAGAGTATTGAGCAAGCGAC
AATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References