Detailed information of TA system TA078861

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 3247688..3248640
• Replicon: chromosome
• Accession: NZ_CP022297
• Organism: Marinobacterium georgiense strain IC961

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: CFI10_RS15640
• Protein ID: WP_206836163.1
• Coordinates: 3248236..3248640 (+)
• Length: 135 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: CFI10_RS15635
• Protein ID: WP_206836160.1
• Coordinates: 3247688..3248239 (+)
• Length: 184 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CFI10_RS15615	3244565..3244891	-	327	WP_206836156.1	preprotein translocase subunit YajC	-
CFI10_RS15620	3244930..3246048	-	1119	WP_206836157.1	tRNA guanosine(34) transglycosylase Tgt	-
CFI10_RS15625	3246063..3247115	-	1053	WP_091827772.1	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	-
CFI10_RS15635	3247688..3248239	+	552	WP_206836160.1	DUF4065 domain-containing protein	Antitoxin
CFI10_RS15640	3248236..3248640	+	405	WP_206836163.1	hypothetical protein	Toxin
CFI10_RS15645	3248910..3249938	-	1029	WP_206836166.1	virulence RhuM family protein	-
CFI10_RS15650	3250196..3250939	-	744	WP_206836169.1	DUF4197 family protein	-
CFI10_RS15655	3251024..3252334	-	1311	WP_206836171.1	guanine deaminase	-
CFI10_RS15660	3252362..3253633	-	1272	WP_206836174.1	translesion error-prone DNA polymerase V subunit UmuC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (27-136)

Sequences

Toxin

Protein

• Length: 135 a.a.
• Molecular weight: 15135.47 Da
• Isoelectric Point: 7.4446

>T78861 WP_206836163.1 NZ_CP022297:3248236-3248640 [Marinobacterium georgiense]
MTQPLIARKGTFFWLTGPVDHMHIIINDPVFCPEAGHELVVDVNITSMTERHDPACVLEAGCHPFITRQSYVFYRDASPF
SATKLAAGVAAGEVRTHEAVDEALYEKVLEGFKVSRFVKPRIKRFLRNHARLID

Nucleotide

• Length: 405 bp

>T78861 NZ_CP022297:3248236-3248640 [Marinobacterium georgiense]
ATGACTCAGCCACTGATAGCAAGAAAAGGGACGTTCTTCTGGCTGACTGGCCCAGTCGACCACATGCACATCATCATCAA
TGATCCTGTCTTCTGCCCAGAAGCGGGTCATGAGCTTGTTGTTGACGTGAACATCACCTCTATGACTGAACGTCATGATC
CGGCTTGTGTTTTAGAAGCTGGTTGCCACCCATTCATCACTCGTCAAAGCTATGTTTTTTACCGCGATGCATCTCCTTTC
AGTGCAACCAAACTAGCTGCTGGCGTAGCTGCTGGAGAAGTTCGGACTCATGAAGCGGTCGATGAGGCACTTTATGAAAA
GGTACTTGAGGGATTTAAGGTCTCGAGATTTGTGAAACCCCGAATTAAGCGCTTCCTTCGAAATCATGCCAGGTTAATTG
ACTAG

Antitoxin

Protein

• Length: 184 a.a.
• Molecular weight: 21378.03 Da
• Isoelectric Point: 5.1009

>AT78861 WP_206836160.1 NZ_CP022297:3247688-3248239 [Marinobacterium georgiense]
MFDDKKVAQMAMYFLGRRGGRMSYLKLMKLLYLADRHSMELYDFPISDDHHVSLPHGPVLSNTLNLITGQVESVAWNSEI
AAEANYEVSLKSTFDRDKLDELSDADIEVMEAIWNQFGEMNRWELRQHTHDHCPEWEDPNGSSFPISPEAIYRAVGRDEH
SAQQLNNELMQRKSLEMIRRNYR

Nucleotide

• Length: 552 bp

>AT78861 NZ_CP022297:3247688-3248239 [Marinobacterium georgiense]
ATGTTTGACGACAAAAAAGTAGCTCAGATGGCTATGTACTTCCTCGGTAGAAGAGGTGGCCGCATGTCTTACTTGAAGCT
AATGAAACTGCTGTACCTGGCAGACCGTCACTCTATGGAACTCTACGACTTCCCTATTTCTGACGATCACCATGTTTCCC
TGCCTCACGGGCCTGTCCTGTCGAACACTCTCAACTTGATTACAGGTCAGGTTGAATCTGTTGCATGGAATAGTGAAATA
GCCGCCGAAGCGAATTATGAAGTTAGCCTGAAGTCTACTTTCGACCGTGACAAGCTGGATGAGCTGAGTGATGCTGACAT
TGAAGTCATGGAGGCCATCTGGAATCAGTTTGGCGAAATGAATCGTTGGGAGCTGAGGCAGCACACTCACGACCACTGCC
CAGAATGGGAAGATCCAAACGGCTCTTCTTTCCCCATCTCACCAGAAGCCATCTATCGTGCAGTTGGTCGAGATGAACAC
TCGGCGCAGCAGCTGAATAATGAGCTGATGCAGCGTAAGTCACTGGAGATGATTCGCCGCAATTACCGATGA