Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 2842355..2842893 Replicon chromosome
Accession NZ_CP022297
Organism Marinobacterium georgiense strain IC961

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag CFI10_RS13615 Protein ID WP_206835314.1
Coordinates 2842597..2842893 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag CFI10_RS13610 Protein ID WP_206835312.1
Coordinates 2842355..2842597 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFI10_RS13590 2838047..2838451 - 405 WP_206835305.1 plasmid mobilization relaxosome protein MobC -
CFI10_RS13595 2838924..2840228 - 1305 WP_206834329.1 IS1380 family transposase -
CFI10_RS13600 2840379..2840795 - 417 WP_206835307.1 IS200/IS605 family transposase -
CFI10_RS13605 2840855..2842180 + 1326 WP_206835309.1 IS200/IS605 family accessory protein TnpB-related protein -
CFI10_RS13610 2842355..2842597 + 243 WP_206835312.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
CFI10_RS13615 2842597..2842893 + 297 WP_206835314.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFI10_RS13620 2842982..2845882 + 2901 WP_206835315.1 aminomethyl-transferring glycine dehydrogenase -
CFI10_RS13625 2845930..2847852 - 1923 WP_206835318.1 polysaccharide biosynthesis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2838924..2840228 1304


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-92)

Antitoxin

Antitoxin ParD

(6-62)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11529.02 Da        Isoelectric Point: 5.8973

>T78860 WP_206835314.1 NZ_CP022297:2842597-2842893 [Marinobacterium georgiense]
MEYILSQLAEEDIINIFVSGAERFGTELAERYHAHLEATFRFLANNPKARPIRSEFTPEVRIHPTGSHLIIYRVEIDNEV
FVIRVRHTHEDWQTQTLP

Download         Length: 297 bp

>T78860 NZ_CP022297:2842597-2842893 [Marinobacterium georgiense]
ATGGAGTACATCCTCAGCCAGCTTGCAGAAGAAGATATCATCAACATTTTTGTTTCTGGCGCTGAACGCTTCGGTACTGA
ATTAGCTGAACGCTATCATGCGCATCTAGAGGCTACATTCCGTTTTCTCGCCAATAACCCCAAGGCAAGGCCGATCAGGA
GTGAGTTCACGCCTGAAGTACGCATTCACCCGACAGGTTCGCACCTGATCATTTATCGTGTTGAAATTGATAATGAGGTG
TTTGTCATTCGAGTCCGCCACACCCACGAAGACTGGCAAACTCAAACGCTTCCGTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9231.17 Da        Isoelectric Point: 6.7245

>AT78860 WP_206835312.1 NZ_CP022297:2842355-2842597 [Marinobacterium georgiense]
MATMNISLPNELKEWVEQQAHTGRYSNSSDYVRDLIRRDQDRASQQHHLQQLISEGMNSGKGSRSMDELRREALSRLASD

Download         Length: 243 bp

>AT78860 NZ_CP022297:2842355-2842597 [Marinobacterium georgiense]
ATGGCAACCATGAATATTTCTTTGCCCAACGAATTGAAAGAGTGGGTCGAGCAGCAGGCGCACACCGGGCGATACAGCAA
TTCCAGCGACTATGTTCGTGACTTGATACGGCGGGACCAGGACCGAGCCAGTCAACAGCATCATTTACAGCAGTTGATTT
CCGAGGGAATGAACAGCGGCAAGGGCTCACGCTCTATGGATGAATTGCGCCGAGAAGCACTGAGCAGACTGGCGTCTGAC
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References