Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe(toxin)
Location 1558365..1558796 Replicon chromosome
Accession NZ_CP022297
Organism Marinobacterium georgiense strain IC961

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CFI10_RS07515 Protein ID WP_206841036.1
Coordinates 1558365..1558628 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CFI10_RS07520 Protein ID WP_206841038.1
Coordinates 1558653..1558796 (+) Length 48 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFI10_RS07490 1554307..1555146 + 840 WP_206841026.1 hypothetical protein -
CFI10_RS07495 1555257..1556195 + 939 WP_206841028.1 hypothetical protein -
CFI10_RS07500 1556391..1557038 + 648 WP_206841029.1 methyltransferase domain-containing protein -
CFI10_RS07505 1557144..1558022 + 879 WP_206841031.1 alpha/beta fold hydrolase -
CFI10_RS07510 1558126..1558368 + 243 WP_206841034.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
CFI10_RS07515 1558365..1558628 + 264 WP_206841036.1 Txe/YoeB family addiction module toxin Toxin
CFI10_RS07520 1558653..1558796 + 144 WP_206841038.1 hypothetical protein Antitoxin
CFI10_RS07525 1558885..1559079 + 195 WP_206841040.1 type II toxin-antitoxin system RelE/ParE family toxin -
CFI10_RS07530 1559123..1559392 + 270 WP_206841042.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
CFI10_RS07535 1559393..1559689 + 297 Protein_1476 type II toxin-antitoxin system RelE/ParE family toxin -
CFI10_RS07540 1559751..1560137 - 387 WP_206841043.1 universal stress protein -
CFI10_RS07545 1560261..1561124 + 864 WP_206841045.1 serine protein kinase RIO -
CFI10_RS07550 1561287..1562039 + 753 WP_206841047.1 glutaredoxin -
CFI10_RS07555 1562160..1562477 + 318 WP_206841048.1 quaternary ammonium compound efflux SMR transporter SugE -
CFI10_RS07560 1562547..1563197 + 651 WP_206841050.1 helix-turn-helix domain-containing protein -
CFI10_RS07565 1563175..1563585 - 411 WP_206841052.1 VOC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1552488..1553930 1442


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10119.73 Da        Isoelectric Point: 9.6583

>T78858 WP_206841036.1 NZ_CP022297:1558365-1558628 [Marinobacterium georgiense]
VTWKLVYTKQAQKDAKKLASSGLKPKAEELLALIAEDPYRKPPPFENLVGDLEGAYSRRINIQHRLVYQVLEDEKVVKVL
RLWSHYE

Download         Length: 264 bp

>T78858 NZ_CP022297:1558365-1558628 [Marinobacterium georgiense]
GTGACATGGAAGTTGGTTTACACCAAACAAGCCCAGAAGGACGCAAAGAAGCTGGCCTCCAGCGGCCTCAAACCAAAAGC
CGAAGAGTTATTGGCACTCATTGCAGAAGATCCGTACCGCAAGCCACCCCCGTTCGAGAACCTGGTTGGTGATCTTGAGG
GTGCCTATTCACGCCGAATCAATATCCAGCACCGTCTGGTATACCAAGTGCTTGAAGACGAGAAAGTGGTAAAAGTCCTC
CGTCTCTGGAGCCACTACGAATGA

Antitoxin


Download         Length: 48 a.a.        Molecular weight: 5423.06 Da        Isoelectric Point: 4.5106

>AT78858 WP_206841038.1 NZ_CP022297:1558653-1558796 [Marinobacterium georgiense]
VDVHEYERMQERLEILEELYKAEEQIASGDGIAHENAKNRVLSKLAP

Download         Length: 144 bp

>AT78858 NZ_CP022297:1558653-1558796 [Marinobacterium georgiense]
GTGGATGTTCACGAGTACGAGAGGATGCAGGAGCGCCTTGAAATTCTGGAAGAGCTATATAAGGCGGAAGAACAGATAGC
ATCCGGTGATGGCATTGCGCATGAAAACGCGAAAAACAGGGTTTTGAGCAAGCTGGCTCCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References