Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2130143..2130411 Replicon chromosome
Accession NZ_CP022279
Organism Escherichia coli strain STEC299

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2130271..2130373 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2130143..2130411 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFI09_RS10985 2126696..2127358 - 663 WP_000944249.1 exodeoxyribonuclease X -
CFI09_RS10990 2127382..2128038 - 657 WP_000011646.1 carbon-nitrogen hydrolase family protein -
CFI09_RS10995 2128140..2128370 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CFI09_RS11000 2128509..2128883 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CFI09_RS11005 2128887..2129759 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
CFI09_RS11010 2129772..2130113 + 342 WP_000976472.1 YebY family protein -
- 2130143..2130411 - 269 - - Antitoxin
- 2130271..2130373 + 103 - - Toxin
CFI09_RS11015 2130508..2131164 + 657 WP_001357783.1 protein-serine/threonine phosphatase -
CFI09_RS11020 2131165..2131356 - 192 WP_001317886.1 YebW family protein -
CFI09_RS11025 2131461..2131697 - 237 WP_001295499.1 DUF1480 family protein -
CFI09_RS11030 2131815..2133254 - 1440 WP_024190479.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T78786 NZ_CP022279:2130271-2130373 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT78786 NZ_CP022279:c2130411-2130143 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References