Detailed information of TA system TA078775

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/YafQ-DinJ
• Location: 1391816..1392344
• Replicon: chromosome
• Accession: NZ_CP022278
• Organism: Neisseria chenwenguii strain 10023

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: BG910_RS06915
• Protein ID: WP_089036210.1
• Coordinates: 1392087..1392344 (+)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: BG910_RS06910
• Protein ID: WP_089036209.1
• Coordinates: 1391816..1392094 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BG910_RS06870	1386857..1387259	+	403	Protein_1339	helix-turn-helix transcriptional regulator	-
BG910_RS06875	1387614..1388333	+	720	WP_089036203.1	septum site-determining protein MinC	-
BG910_RS06880	1388366..1389178	+	813	WP_089036204.1	septum site-determining protein MinD	-
BG910_RS06885	1389182..1389442	+	261	WP_089036205.1	cell division topological specificity factor MinE	-
BG910_RS06890	1389446..1390366	+	921	WP_089036206.1	LysR family transcriptional regulator	-
BG910_RS06900	1390717..1390974	+	258	WP_089036207.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
BG910_RS06905	1390974..1391393	+	420	WP_089036208.1	type II toxin-antitoxin system VapC family toxin	-
BG910_RS06910	1391816..1392094	+	279	WP_089036209.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
BG910_RS06915	1392087..1392344	+	258	WP_089036210.1	type II toxin-antitoxin system YafQ family toxin	Toxin
BG910_RS06920	1392930..1393373	+	444	WP_089036211.1	pilin	-
BG910_RS06925	1393473..1393916	+	444	WP_089036212.1	pilin	-
BG910_RS06930	1393939..1395357	+	1419	WP_089036213.1	sulfatase-like hydrolase/transferase	-
BG910_RS06935	1395671..1395979	+	309	WP_089036214.1	transcriptional regulator	-
BG910_RS06940	1395976..1396284	+	309	WP_089036215.1	type II toxin-antitoxin system MqsA family antitoxin	-
BG910_RS06945	1396331..1397134	-	804	WP_089036216.1	competence/damage-inducible protein A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, YafQ-like toxin (2-85)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (7-67)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10061.54 Da
• Isoelectric Point: 7.5169

>T78775 WP_089036210.1 NZ_CP022278:1392087-1392344 [Neisseria chenwenguii]
MRKIKKSRSFDKDFKKHGLSENLIEALYHLIHEQPLPEKYRDHALAGNFKGYRDCHIRPDLVLIYRLTDDAVELHMLDSH
SEIFG

Nucleotide

• Length: 258 bp

>T78775 NZ_CP022278:1392087-1392344 [Neisseria chenwenguii]
ATGCGTAAAATCAAAAAGTCCCGTTCGTTTGACAAAGATTTCAAAAAACACGGCTTGAGTGAAAACCTGATTGAAGCCCT
ATACCACCTGATTCATGAACAACCCCTGCCTGAAAAATACCGTGACCATGCGTTGGCCGGTAATTTCAAAGGCTACCGCG
ACTGCCATATCAGACCCGATTTAGTATTGATTTACCGTCTGACCGACGATGCAGTAGAGCTGCATATGCTCGATTCACAT
TCAGAAATCTTCGGCTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10451.64 Da
• Isoelectric Point: 4.5843

>AT78775 WP_089036209.1 NZ_CP022278:1391816-1392094 [Neisseria chenwenguii]
MASTNFNIRLEQSLKDRAFPVIESYGLTPAQAFKLFLNQVAETNTLPLSFDYRKNRLTPQAEARLRQSAEEMADGSFTES
SFEEWIGQSKDA

Nucleotide

• Length: 279 bp

>AT78775 NZ_CP022278:1391816-1392094 [Neisseria chenwenguii]
ATGGCTTCCACCAATTTCAACATCCGGCTCGAGCAAAGCCTGAAAGACCGCGCATTTCCCGTTATCGAAAGCTACGGCCT
GACGCCCGCGCAGGCATTCAAGCTGTTTCTAAACCAAGTTGCCGAAACCAACACCCTGCCGCTTTCTTTCGATTACCGCA
AAAACAGACTGACTCCGCAGGCAGAGGCCAGATTGCGCCAATCCGCAGAAGAAATGGCAGACGGCAGTTTTACAGAAAGC
AGCTTTGAAGAATGGATAGGGCAATCCAAAGATGCGTAA