Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | stbE-relB/ParE-YafN |
| Location | 1320063..1320582 | Replicon | chromosome |
| Accession | NZ_CP022278 | ||
| Organism | Neisseria chenwenguii strain 10023 | ||
Toxin (Protein)
| Gene name | stbE | Uniprot ID | - |
| Locus tag | BG910_RS06550 | Protein ID | WP_089036148.1 |
| Coordinates | 1320295..1320582 (+) | Length | 96 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | - |
| Locus tag | BG910_RS06545 | Protein ID | WP_089036147.1 |
| Coordinates | 1320063..1320305 (+) | Length | 81 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BG910_RS06505 | 1315241..1315540 | + | 300 | WP_089036143.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| BG910_RS06510 | 1315587..1315973 | - | 387 | WP_089036144.1 | type II toxin-antitoxin system VapC family toxin | - |
| BG910_RS06515 | 1315970..1316215 | - | 246 | WP_089036145.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
| BG910_RS06520 | 1316310..1316744 | - | 435 | WP_157694043.1 | hypothetical protein | - |
| BG910_RS06525 | 1317403..1317801 | + | 399 | WP_198344763.1 | phosphoglycerate kinase | - |
| BG910_RS06530 | 1317870..1318646 | + | 777 | WP_089035856.1 | N-6 DNA methylase | - |
| BG910_RS06535 | 1318696..1319157 | + | 462 | WP_089035857.1 | hypothetical protein | - |
| BG910_RS06540 | 1319132..1319692 | + | 561 | WP_089035858.1 | hypothetical protein | - |
| BG910_RS12275 | 1319697..1320035 | + | 339 | WP_157694044.1 | hypothetical protein | - |
| BG910_RS06545 | 1320063..1320305 | + | 243 | WP_089036147.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| BG910_RS06550 | 1320295..1320582 | + | 288 | WP_089036148.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| BG910_RS12280 | 1320615..1320743 | - | 129 | WP_123805482.1 | DUF4113 domain-containing protein | - |
| BG910_RS06555 | 1320721..1321587 | - | 867 | WP_089036149.1 | Fic family protein | - |
| BG910_RS06560 | 1321594..1321803 | - | 210 | WP_089036150.1 | hypothetical protein | - |
| BG910_RS06565 | 1321804..1322424 | - | 621 | WP_089036151.1 | recombinase family protein | - |
| BG910_RS06570 | 1322433..1323107 | - | 675 | WP_089036152.1 | Fic family protein | - |
| BG910_RS06575 | 1323319..1323543 | + | 225 | WP_089037174.1 | TraY domain-containing protein | - |
| BG910_RS06580 | 1323527..1323802 | + | 276 | WP_089036153.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| BG910_RS06585 | 1323857..1324141 | - | 285 | WP_089036154.1 | virulence factor | - |
| BG910_RS06590 | 1324141..1324341 | - | 201 | WP_089037175.1 | DUF5397 family protein | - |
| BG910_RS06595 | 1324475..1325527 | - | 1053 | WP_089036155.1 | traS protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 96 a.a. Molecular weight: 10879.74 Da Isoelectric Point: 10.5009
>T78772 WP_089036148.1 NZ_CP022278:1320295-1320582 [Neisseria chenwenguii]
MTYKLAFLPSARAEWDKLDGSVKQVFKKKLAERLETPRVPSAALHNMHDCYKIKLKRAGYRLVYRVDDNIVTITVVSVGR
RADLAVYQAAKSRLE
MTYKLAFLPSARAEWDKLDGSVKQVFKKKLAERLETPRVPSAALHNMHDCYKIKLKRAGYRLVYRVDDNIVTITVVSVGR
RADLAVYQAAKSRLE
Download Length: 288 bp
>T78772 NZ_CP022278:1320295-1320582 [Neisseria chenwenguii]
ATGACCTATAAACTGGCGTTCCTGCCGTCTGCCCGTGCGGAATGGGACAAGCTCGACGGCAGCGTGAAACAGGTGTTCAA
GAAAAAATTGGCGGAACGGCTGGAAACCCCGCGTGTCCCGTCGGCCGCCCTGCACAATATGCACGACTGCTACAAAATCA
AACTCAAACGGGCAGGCTACCGCTTGGTTTACCGTGTGGACGACAACATCGTTACGATAACGGTGGTATCCGTCGGCCGC
AGGGCAGACTTGGCTGTTTATCAGGCTGCTAAAAGCAGGTTGGAATAA
ATGACCTATAAACTGGCGTTCCTGCCGTCTGCCCGTGCGGAATGGGACAAGCTCGACGGCAGCGTGAAACAGGTGTTCAA
GAAAAAATTGGCGGAACGGCTGGAAACCCCGCGTGTCCCGTCGGCCGCCCTGCACAATATGCACGACTGCTACAAAATCA
AACTCAAACGGGCAGGCTACCGCTTGGTTTACCGTGTGGACGACAACATCGTTACGATAACGGTGGTATCCGTCGGCCGC
AGGGCAGACTTGGCTGTTTATCAGGCTGCTAAAAGCAGGTTGGAATAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 8868.07 Da Isoelectric Point: 4.3077
>AT78772 WP_089036147.1 NZ_CP022278:1320063-1320305 [Neisseria chenwenguii]
MNPILSDVAVSVTELKRNYAAIVAEAEGAVAVLNHNKPESYLIPAQQYEALMDYIEDLADARKIMERAGERAVEVNLHDL
MNPILSDVAVSVTELKRNYAAIVAEAEGAVAVLNHNKPESYLIPAQQYEALMDYIEDLADARKIMERAGERAVEVNLHDL
Download Length: 243 bp
>AT78772 NZ_CP022278:1320063-1320305 [Neisseria chenwenguii]
ATGAATCCGATTCTATCCGACGTAGCCGTCAGCGTAACCGAATTGAAACGCAACTATGCGGCTATCGTAGCAGAAGCTGA
AGGTGCAGTTGCGGTACTTAACCACAACAAGCCTGAATCCTACCTGATTCCGGCGCAGCAGTACGAAGCCTTGATGGACT
ACATCGAAGACTTGGCTGATGCCCGTAAAATTATGGAACGCGCCGGAGAACGGGCCGTAGAGGTCAATCTGCATGACCTA
TAA
ATGAATCCGATTCTATCCGACGTAGCCGTCAGCGTAACCGAATTGAAACGCAACTATGCGGCTATCGTAGCAGAAGCTGA
AGGTGCAGTTGCGGTACTTAACCACAACAAGCCTGAATCCTACCTGATTCCGGCGCAGCAGTACGAAGCCTTGATGGACT
ACATCGAAGACTTGGCTGATGCCCGTAAAATTATGGAACGCGCCGGAGAACGGGCCGTAGAGGTCAATCTGCATGACCTA
TAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|