Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-parE/ParE-RHH
Location 1314966..1315540 Replicon chromosome
Accession NZ_CP022278
Organism Neisseria chenwenguii strain 10023

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BG910_RS06505 Protein ID WP_089036143.1
Coordinates 1315241..1315540 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BG910_RS06500 Protein ID WP_089036142.1
Coordinates 1314966..1315253 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BG910_RS06465 1310109..1310735 + 627 WP_089036135.1 hypothetical protein -
BG910_RS06470 1310721..1310969 - 249 WP_157694042.1 hypothetical protein -
BG910_RS06475 1311972..1312373 - 402 WP_089036137.1 type II toxin-antitoxin system VapC family toxin -
BG910_RS06480 1312370..1312630 - 261 WP_089036138.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
BG910_RS06485 1312743..1313342 - 600 WP_089036139.1 LexA family transcriptional regulator -
BG910_RS06490 1313468..1313677 + 210 WP_089036140.1 helix-turn-helix domain-containing protein -
BG910_RS06495 1313684..1314484 + 801 WP_089036141.1 hypothetical protein -
BG910_RS06500 1314966..1315253 + 288 WP_089036142.1 ribbon-helix-helix domain-containing protein Antitoxin
BG910_RS06505 1315241..1315540 + 300 WP_089036143.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BG910_RS06510 1315587..1315973 - 387 WP_089036144.1 type II toxin-antitoxin system VapC family toxin -
BG910_RS06515 1315970..1316215 - 246 WP_089036145.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
BG910_RS06520 1316310..1316744 - 435 WP_157694043.1 hypothetical protein -
BG910_RS06525 1317403..1317801 + 399 WP_198344763.1 phosphoglycerate kinase -
BG910_RS06530 1317870..1318646 + 777 WP_089035856.1 N-6 DNA methylase -
BG910_RS06535 1318696..1319157 + 462 WP_089035857.1 hypothetical protein -
BG910_RS06540 1319132..1319692 + 561 WP_089035858.1 hypothetical protein -
BG910_RS12275 1319697..1320035 + 339 WP_157694044.1 hypothetical protein -
BG910_RS06545 1320063..1320305 + 243 WP_089036147.1 type II toxin-antitoxin system Phd/YefM family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-45)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11267.85 Da        Isoelectric Point: 6.4653

>T78771 WP_089036143.1 NZ_CP022278:1315241-1315540 [Neisseria chenwenguii]
MPQVMLTEHATADLRRLYDFLAPKNEQAARNAVKAVKDALAGLAQFPATGRFFDDEYREWPVSFGDAGYTVLYRMDSEIV
VIVAIKHQRELSYSFPVKN

Download         Length: 300 bp

>T78771 NZ_CP022278:1315241-1315540 [Neisseria chenwenguii]
ATGCCACAAGTAATGTTAACCGAACATGCGACGGCTGATTTACGACGGCTCTATGATTTTTTAGCACCGAAAAACGAACA
AGCTGCACGAAATGCGGTAAAGGCCGTTAAGGACGCTTTGGCAGGTTTGGCACAATTTCCTGCCACCGGCCGTTTTTTTG
ATGATGAATACCGGGAATGGCCGGTTTCCTTCGGAGATGCAGGCTATACCGTTTTATATCGGATGGATTCTGAAATCGTT
GTGATTGTGGCGATTAAGCACCAACGGGAATTGAGTTACAGTTTTCCGGTTAAGAATTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10890.43 Da        Isoelectric Point: 6.0850

>AT78771 WP_089036142.1 NZ_CP022278:1314966-1315253 [Neisseria chenwenguii]
MKPQTVPVAVKLPLEIRDRLKAVAETQDRSVHWLMREAVNQFLEREEQKAALRAAADASWAHYQETGLHVTLEEANVWMD
TIIEGREAGELKCHK

Download         Length: 288 bp

>AT78771 NZ_CP022278:1314966-1315253 [Neisseria chenwenguii]
ATGAAACCGCAAACCGTGCCTGTGGCCGTTAAATTACCGCTAGAAATCAGAGACCGTTTGAAAGCAGTTGCCGAAACCCA
AGATCGCTCTGTGCATTGGTTGATGCGGGAAGCGGTCAACCAATTTTTGGAACGTGAAGAGCAGAAAGCTGCTTTACGTG
CCGCAGCCGATGCTTCTTGGGCACACTATCAAGAAACCGGCCTGCATGTTACGTTGGAAGAGGCAAATGTATGGATGGAT
ACAATTATTGAAGGGAGAGAAGCCGGGGAATTGAAATGCCACAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References