Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-YefM
Location 964177..964685 Replicon chromosome
Accession NZ_CP022278
Organism Neisseria chenwenguii strain 10023

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BG910_RS04765 Protein ID WP_089035854.1
Coordinates 964422..964685 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BG910_RS04760 Protein ID WP_089035853.1
Coordinates 964177..964425 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BG910_RS12170 959614..960183 + 570 WP_157694024.1 hypothetical protein -
BG910_RS04735 960131..960526 - 396 WP_157694025.1 hypothetical protein -
BG910_RS04740 960504..960857 - 354 WP_157694026.1 hypothetical protein -
BG910_RS04745 961843..962571 - 729 WP_089035850.1 LexA family transcriptional regulator -
BG910_RS04750 962646..962858 + 213 WP_089035851.1 helix-turn-helix domain-containing protein -
BG910_RS04755 962868..963653 + 786 WP_089035852.1 hypothetical protein -
BG910_RS04760 964177..964425 + 249 WP_089035853.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BG910_RS04765 964422..964685 + 264 WP_089035854.1 Txe/YoeB family addiction module toxin Toxin
BG910_RS04770 964727..965107 - 381 WP_089035855.1 hypothetical protein -
BG910_RS04775 965759..966157 + 399 WP_198344763.1 phosphoglycerate kinase -
BG910_RS04780 966226..967002 + 777 WP_089035856.1 N-6 DNA methylase -
BG910_RS04785 967052..967513 + 462 WP_089035857.1 hypothetical protein -
BG910_RS04790 967488..968048 + 561 WP_089035858.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10338.80 Da        Isoelectric Point: 10.2589

>T78768 WP_089035854.1 NZ_CP022278:964422-964685 [Neisseria chenwenguii]
VKAHRFTQSAAEDLAYWKKHDLKKVGRIKALLDDIKANHPRGIGKPEPLRHQKSGLWSRRIDREHRLVYSVEEDTVTVYA
CRYHYER

Download         Length: 264 bp

>T78768 NZ_CP022278:964422-964685 [Neisseria chenwenguii]
GTGAAGGCACACCGTTTCACACAAAGTGCGGCAGAAGACTTGGCGTATTGGAAAAAACACGATTTGAAGAAAGTCGGTCG
CATCAAAGCCCTGCTGGACGATATTAAGGCCAACCACCCGAGGGGAATCGGCAAACCGGAACCGCTGCGCCATCAAAAAT
CGGGCTTATGGTCGCGACGGATAGACCGTGAACACAGGTTGGTTTATTCCGTTGAAGAAGACACTGTTACCGTTTATGCC
TGCCGTTATCATTATGAACGTTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9196.27 Da        Isoelectric Point: 4.0871

>AT78768 WP_089035853.1 NZ_CP022278:964177-964425 [Neisseria chenwenguii]
MDTVVSYTAAREDLANIMTRVCEDHVVTHITRRNGGNCILMSEEEYNSIMETLYLFGNPVNAARLEQSIGEAEQGQFAEV
EL

Download         Length: 249 bp

>AT78768 NZ_CP022278:964177-964425 [Neisseria chenwenguii]
ATGGATACCGTAGTCAGCTACACCGCCGCCCGCGAAGACTTGGCCAATATCATGACCAGAGTTTGCGAAGACCATGTGGT
AACCCACATTACCCGCAGAAACGGCGGCAACTGCATTTTGATGTCGGAAGAAGAATACAACTCGATTATGGAGACGCTTT
ATCTGTTTGGAAATCCGGTCAATGCGGCCCGTTTGGAACAATCCATCGGCGAAGCCGAACAAGGTCAATTTGCAGAGGTA
GAGCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References