Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 375336..376815 Replicon chromosome
Accession NZ_CP022271
Organism Hyphomonas sp. KY3

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag CFA77_RS01960 Protein ID WP_206992028.1
Coordinates 375336..376205 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag CFA77_RS01965 Protein ID WP_206992029.1
Coordinates 376198..376815 (-) Length 206 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFA77_RS01950 370367..372295 - 1929 WP_206992026.1 AAA family ATPase -
CFA77_RS01955 372292..375273 - 2982 WP_206992027.1 AAA family ATPase -
CFA77_RS01960 375336..376205 - 870 WP_206992028.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CFA77_RS01965 376198..376815 - 618 WP_206992029.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
CFA77_RS01970 377209..378405 + 1197 WP_206992030.1 DUF932 domain-containing protein -
CFA77_RS01975 378531..380588 + 2058 WP_206992031.1 ParB N-terminal domain-containing protein -
CFA77_RS01980 380679..381719 + 1041 WP_206992032.1 toprim domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 354111..406882 52771


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-265)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(13-56)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 32459.06 Da        Isoelectric Point: 4.7435

>T78743 WP_206992028.1 NZ_CP022271:c376205-375336 [Hyphomonas sp. KY3]
MAREIKNIGASVRARLLRLSKANGQSFDLVLTRFALERLLFRLSRSPHADRFVLKGAMLMMSWFDDPHRGTRDLDLLGFG
DPSEDAMMATFREILAQDVEDGAVFDPDTLRVDRIREDLDYGGLRLRAIATVGGARINLTIDIGFGDALEPGTEVVDYPV
MLDLPAPRLRAYARETVIAEKFEAMVALGRANSRMKDFYDIWILSRSFSFDDDRLAQAIAATFARRETAIPSEPPDALTP
AFAADEQRQRQWRAFVEDVAIDPGPLAPVLEELADFLMPRARRANELSQ

Download         Length: 870 bp

>T78743 NZ_CP022271:c376205-375336 [Hyphomonas sp. KY3]
ATGGCTAGGGAGATCAAGAATATCGGCGCCTCGGTGCGCGCCCGGCTTCTCAGGCTCTCCAAGGCGAACGGGCAGAGTTT
CGATCTCGTGCTCACGCGCTTTGCGCTGGAACGCCTTCTCTTCCGCCTCAGCCGGTCGCCCCATGCCGATCGTTTCGTGT
TGAAAGGCGCGATGCTGATGATGAGCTGGTTCGACGATCCGCACCGCGGCACGCGTGATCTCGATTTGCTGGGTTTCGGC
GATCCGAGCGAGGACGCGATGATGGCGACATTCCGGGAAATCCTCGCCCAGGATGTCGAGGACGGCGCCGTGTTCGATCC
GGACACGCTACGCGTCGATCGCATTCGCGAGGATCTCGACTATGGCGGTCTCCGGCTGCGCGCCATCGCTACGGTTGGCG
GCGCCCGGATCAACCTCACGATCGATATTGGTTTTGGCGATGCGCTAGAGCCCGGGACGGAAGTCGTCGACTACCCGGTC
ATGCTCGACCTGCCCGCGCCGAGGCTGCGCGCCTATGCGCGGGAGACGGTTATCGCCGAGAAGTTCGAAGCGATGGTGGC
GTTGGGCCGGGCGAACAGCCGGATGAAGGACTTCTACGACATCTGGATTCTCAGCCGCTCATTCAGTTTCGATGACGACA
GGCTTGCGCAGGCGATCGCCGCGACCTTCGCGCGGCGCGAAACGGCGATCCCGTCCGAACCGCCCGACGCGCTTACGCCG
GCATTTGCGGCGGACGAACAAAGGCAGCGACAGTGGCGCGCCTTTGTCGAAGACGTTGCCATTGATCCAGGGCCTCTTGC
GCCGGTCCTTGAGGAACTCGCTGACTTCCTGATGCCACGGGCCAGGCGGGCAAACGAACTGAGTCAGTAG

Antitoxin


Download         Length: 206 a.a.        Molecular weight: 22260.76 Da        Isoelectric Point: 9.9372

>AT78743 WP_206992029.1 NZ_CP022271:c376815-376198 [Hyphomonas sp. KY3]
MSRTRSQREIARDLLAARGIMRLAELREAGVTAATVSRMEKDGEVIRLARGLYQLPDAELDANHSLAEAAKRFPKGVICL
VSALAFHGITDQLPKKVWIAIGRNDWTPKPSDMPIRVLRFSDDLLAESVETHVIEGVSVKVFGVAKTVADCFRHRGKIGL
AVALEGLQEALRQRKATPAEIARAADTGGVGTVIRPYLEALTANG

Download         Length: 618 bp

>AT78743 NZ_CP022271:c376815-376198 [Hyphomonas sp. KY3]
ATGTCCCGAACTCGGTCCCAACGCGAGATAGCCCGCGATCTCCTCGCGGCGCGTGGGATTATGCGCCTCGCGGAACTCAG
AGAAGCCGGTGTCACTGCCGCAACCGTCAGCCGCATGGAGAAGGATGGCGAGGTCATCCGCCTGGCGCGCGGGCTCTACC
AGCTTCCCGACGCAGAGCTCGATGCAAACCACAGCCTCGCCGAGGCGGCCAAGCGCTTCCCCAAAGGGGTGATCTGCCTC
GTCTCGGCGCTCGCCTTTCATGGAATCACGGATCAGCTTCCCAAGAAGGTGTGGATAGCGATCGGCCGGAACGACTGGAC
GCCGAAGCCGAGCGATATGCCGATCCGTGTACTGCGTTTCTCGGACGATCTGCTTGCCGAAAGCGTCGAGACCCACGTGA
TCGAAGGCGTATCGGTAAAGGTATTCGGCGTGGCAAAGACTGTCGCAGACTGTTTCCGTCATCGCGGCAAGATCGGTCTC
GCCGTCGCGCTCGAAGGCCTGCAAGAGGCTCTGCGGCAACGTAAAGCCACACCCGCGGAGATCGCGAGGGCAGCGGATAC
AGGCGGGGTCGGGACCGTGATCCGCCCCTATCTGGAGGCACTGACCGCCAATGGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References