78742

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) EcnAB/-
Location 4624012..4624372 Replicon chromosome
Accession NZ_CP022270
Organism Xanthomonas citri pv. vignicola strain CFBP7113

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcvCFBP7113P_RS20765 Protein ID WP_005914328.1
Coordinates 4624012..4624146 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcvCFBP7113P_RS20770 Protein ID WP_003486606.1
Coordinates 4624220..4624372 (-) Length 51 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcvCFBP7113P_RS20750 4621036..4622079 - 1044 WP_089096272.1 MBL fold metallo-hydrolase -
XcvCFBP7113P_RS20755 4622109..4623398 - 1290 WP_089096273.1 tryptophan--tRNA ligase -
XcvCFBP7113P_RS20760 4623571..4623780 - 210 WP_016904514.1 CsbD family protein -
XcvCFBP7113P_RS20765 4624012..4624146 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcvCFBP7113P_RS20770 4624220..4624372 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcvCFBP7113P_RS20775 4624479..4625402 - 924 WP_007966941.1 arginase -
XcvCFBP7113P_RS20780 4625723..4626175 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcvCFBP7113P_RS20785 4626239..4626598 + 360 WP_003486613.1 hypothetical protein -
XcvCFBP7113P_RS20790 4626695..4627612 + 918 WP_089096274.1 hypothetical protein -
XcvCFBP7113P_RS20795 4627609..4628151 + 543 WP_003486615.1 GTPase -
XcvCFBP7113P_RS20800 4628631..4629314 + 684 WP_089096275.1 dTMP kinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(23-42)

Antitoxin

(23-42)


Sequences


Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T78742 WP_005914328.1 NZ_CP022270:c4624146-4624012 [Xanthomonas citri pv. vignicola]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T78742 NZ_CP022270:c4624146-4624012 [Xanthomonas citri pv. vignicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT78742 WP_003486606.1 NZ_CP022270:c4624372-4624220 [Xanthomonas citri pv. vignicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT78742 NZ_CP022270:c4624372-4624220 [Xanthomonas citri pv. vignicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6


Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References