78739

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4567831..4568192 Replicon chromosome
Accession NZ_CP022267
Organism Xanthomonas citri pv. vignicola strain CFBP7112

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcvCFBP7112P_RS20195 Protein ID WP_005914328.1
Coordinates 4567831..4567965 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcvCFBP7112P_RS20200 Protein ID WP_003486606.1
Coordinates 4568040..4568192 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcvCFBP7112P_RS20180 4564861..4565904 - 1044 WP_089142375.1 MBL fold metallo-hydrolase -
XcvCFBP7112P_RS20185 4565934..4567223 - 1290 WP_089142376.1 tryptophan--tRNA ligase -
XcvCFBP7112P_RS20190 4567396..4567605 - 210 WP_016904514.1 CsbD family protein -
XcvCFBP7112P_RS20195 4567831..4567965 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcvCFBP7112P_RS20200 4568040..4568192 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcvCFBP7112P_RS20205 4568299..4569222 - 924 WP_007966941.1 arginase -
XcvCFBP7112P_RS20210 4569543..4569995 + 453 WP_007974175.1 roadblock/LC7 domain-containing protein -
XcvCFBP7112P_RS20215 4570059..4570418 + 360 WP_003486613.1 hypothetical protein -
XcvCFBP7112P_RS20220 4570515..4571432 + 918 WP_089096274.1 hypothetical protein -
XcvCFBP7112P_RS20225 4571429..4571971 + 543 WP_003486615.1 GTPase -
XcvCFBP7112P_RS20230 4572451..4573134 + 684 WP_089142377.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T78739 WP_005914328.1 NZ_CP022267:c4567965-4567831 [Xanthomonas citri pv. vignicola]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T78739 NZ_CP022267:c4567965-4567831 [Xanthomonas citri pv. vignicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT78739 WP_003486606.1 NZ_CP022267:c4568192-4568040 [Xanthomonas citri pv. vignicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT78739 NZ_CP022267:c4568192-4568040 [Xanthomonas citri pv. vignicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAGTGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References