Detailed information of TA system TA078738

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 65288..65832
• Replicon: chromosome
• Accession: NZ_CP022267
• Organism: Xanthomonas citri pv. vignicola strain CFBP7112

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: XcvCFBP7112P_RS00300
• Protein ID: WP_089140647.1
• Coordinates: 65533..65832 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7Z7EKF2
• Locus tag: XcvCFBP7112P_RS00295
• Protein ID: WP_029818122.1
• Coordinates: 65288..65545 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XcvCFBP7112P_RS00280	60385..61890	-	1506	WP_089140646.1	ribonuclease H-like domain-containing protein	-
XcvCFBP7112P_RS00285	61887..64382	-	2496	WP_202988589.1	DEAD/DEAH box helicase	-
XcvCFBP7112P_RS00290	64560..65222	+	663	WP_202988590.1	hemolysin III family protein	-
XcvCFBP7112P_RS00295	65288..65545	+	258	WP_029818122.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
XcvCFBP7112P_RS00300	65533..65832	+	300	WP_089140647.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XcvCFBP7112P_RS00310	66012..66911	-	900	WP_089140648.1	SDR family NAD(P)-dependent oxidoreductase	-
XcvCFBP7112P_RS00315	66971..67708	-	738	WP_089140649.1	SDR family oxidoreductase	-
XcvCFBP7112P_RS00320	67834..68745	+	912	WP_057663388.1	LysR family transcriptional regulator	-
XcvCFBP7112P_RS00325	68960..70033	-	1074	WP_089142558.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11248.91 Da
• Isoelectric Point: 8.0616

>T78738 WP_089140647.1 NZ_CP022267:65533-65832 [Xanthomonas citri pv. vignicola]
MAEIIWSVPALADLDAIADYTAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELERSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T78738 NZ_CP022267:65533-65832 [Xanthomonas citri pv. vignicola]
ATGGCTGAAATAATCTGGTCAGTGCCGGCATTGGCTGATCTGGACGCAATTGCCGACTACACCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACATCCGGACAGCGGAAGCCGGCCAC
AGGAACTCGAGCGCTCGCGCTATCGCCAAATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9632.12 Da
• Isoelectric Point: 8.6223

>AT78738 WP_029818122.1 NZ_CP022267:65288-65545 [Xanthomonas citri pv. vignicola]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVADGRTLSHEQAQQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT78738 NZ_CP022267:65288-65545 [Xanthomonas citri pv. vignicola]
ATGCGCACCGAACTTGTCACCACGCTTAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Antitoxin

• AlphaFold DB: A0A7Z7EKF2