78736

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 608610..608971 Replicon chromosome
Accession NZ_CP022263
Organism Xanthomonas citri pv. vignicola strain CFBP7111

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag XcvCFBP7111P_RS02755 Protein ID WP_005914328.1
Coordinates 608837..608971 (+) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag XcvCFBP7111P_RS02750 Protein ID WP_003486606.1
Coordinates 608610..608762 (+) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XcvCFBP7111P_RS02715 603668..604351 - 684 WP_089111469.1 dTMP kinase -
XcvCFBP7111P_RS02725 604831..605373 - 543 WP_003486615.1 GTPase -
XcvCFBP7111P_RS02730 605370..606287 - 918 WP_089096274.1 hypothetical protein -
XcvCFBP7111P_RS02735 606384..606743 - 360 WP_003486613.1 hypothetical protein -
XcvCFBP7111P_RS02740 606807..607259 - 453 WP_089111471.1 roadblock/LC7 domain-containing protein -
XcvCFBP7111P_RS02745 607580..608503 + 924 WP_007966941.1 arginase -
XcvCFBP7111P_RS02750 608610..608762 + 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
XcvCFBP7111P_RS02755 608837..608971 + 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
XcvCFBP7111P_RS02760 609197..609406 + 210 WP_016904514.1 CsbD family protein -
XcvCFBP7111P_RS02765 609579..610868 + 1290 WP_007966942.1 tryptophan--tRNA ligase -
XcvCFBP7111P_RS02770 610898..611941 + 1044 WP_089111472.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T78736 WP_005914328.1 NZ_CP022263:608837-608971 [Xanthomonas citri pv. vignicola]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T78736 NZ_CP022263:608837-608971 [Xanthomonas citri pv. vignicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT78736 WP_003486606.1 NZ_CP022263:608610-608762 [Xanthomonas citri pv. vignicola]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT78736 NZ_CP022263:608610-608762 [Xanthomonas citri pv. vignicola]
ATGAAGCGACTGCTGACACTGATGGTGCTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCCGGCGC
CGGCAAGGACATGCAGGGTGCGGGCAACAAGGTCGAGAAAACGGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References