Detailed information of TA system TA078735

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Phd(antitoxin)
• Location: 66462..67006
• Replicon: chromosome
• Accession: NZ_CP022263
• Organism: Xanthomonas citri pv. vignicola strain CFBP7111

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: XcvCFBP7111P_RS00305
• Protein ID: WP_089111269.1
• Coordinates: 66707..67006 (+)
• Length: 100 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7Z7EKF2
• Locus tag: XcvCFBP7111P_RS00300
• Protein ID: WP_029818122.1
• Coordinates: 66462..66719 (+)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XcvCFBP7111P_RS00285	61607..63064	-	1458	WP_089111268.1	ribonuclease H-like domain-containing protein	-
XcvCFBP7111P_RS00290	63061..65556	-	2496	WP_167382218.1	DEAD/DEAH box helicase	-
XcvCFBP7111P_RS00295	65734..66396	+	663	WP_029818121.1	hemolysin III family protein	-
XcvCFBP7111P_RS00300	66462..66719	+	258	WP_029818122.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
XcvCFBP7111P_RS00305	66707..67006	+	300	WP_089111269.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
XcvCFBP7111P_RS00315	67186..68085	-	900	WP_089111270.1	SDR family NAD(P)-dependent oxidoreductase	-
XcvCFBP7111P_RS00320	68145..68882	-	738	WP_089111271.1	SDR family oxidoreductase	-
XcvCFBP7111P_RS00325	69008..69919	+	912	WP_089111272.1	LysR family transcriptional regulator	-
XcvCFBP7111P_RS00335	70134..71207	-	1074	WP_089113427.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 100 a.a.
• Molecular weight: 11260.02 Da
• Isoelectric Point: 9.7235

>T78735 WP_089111269.1 NZ_CP022263:66707-67006 [Xanthomonas citri pv. vignicola]
MAEIIWSVPALADLDAIADYIAIDNAPAAAALVKRVFAHVEQLIEHPDSGSRPQELKRSRYRQIVEPPCRVFYRVDGQRI
VLVHVMRSERALRGNRLSR

Nucleotide

• Length: 300 bp

>T78735 NZ_CP022263:66707-67006 [Xanthomonas citri pv. vignicola]
ATGGCTGAAATAATCTGGTCGGTGCCGGCATTGGCTGATCTGGACGCAATCGCCGACTACATCGCAATCGATAACGCACC
CGCTGCAGCGGCGCTGGTGAAACGGGTGTTCGCGCACGTTGAGCAATTGATTGAACACCCGGACAGCGGAAGCCGGCCAC
AGGAACTCAAGCGCTCGCGCTATCGCCAGATTGTCGAACCACCTTGCCGCGTGTTCTACCGCGTGGATGGGCAGCGCATC
GTGCTGGTGCACGTAATGCGGTCGGAGCGCGCGCTTCGCGGGAACCGTCTTTCACGCTGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9632.12 Da
• Isoelectric Point: 8.6223

>AT78735 WP_029818122.1 NZ_CP022263:66462-66719 [Xanthomonas citri pv. vignicola]
MRTELVTTLKRQATELLAAAERDKEPILITQHGLPSAYLVDVASYERMQQRIALLEGIARGEMAVADGRTLSHEQAQQRM
ARWLK

Nucleotide

• Length: 258 bp

>AT78735 NZ_CP022263:66462-66719 [Xanthomonas citri pv. vignicola]
ATGCGCACCGAACTTGTCACCACGCTCAAGCGTCAGGCGACCGAACTCCTTGCAGCTGCAGAGCGCGACAAGGAGCCAAT
CCTGATCACACAGCACGGTTTACCCAGTGCCTATCTGGTGGATGTTGCCAGCTATGAGCGCATGCAGCAGCGCATTGCGC
TCCTCGAAGGAATCGCCCGGGGAGAAATGGCAGTCGCGGACGGCCGTACGCTGAGCCATGAACAGGCACAGCAACGCATG
GCGCGATGGCTGAAATAA

Structures

Antitoxin

• AlphaFold DB: A0A7Z7EKF2