Detailed information of TA system TA078674

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 8352961..8353799
• Replicon: chromosome
• Accession: NZ_CP022222
• Organism: Bradyrhizobium sp. CCBAU 051011

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: ACH79_RS39250
• Protein ID: WP_161855585.1
• Coordinates: 8352961..8353494 (-)
• Length: 178 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: -
• Locus tag: ACH79_RS39255
• Protein ID: WP_161855586.1
• Coordinates: 8353482..8353799 (-)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACH79_RS39215	8348275..8348772	+	498	WP_161855580.1	hypothetical protein	-
ACH79_RS39220	8348788..8349512	-	725	Protein_7833	Fic family protein	-
ACH79_RS39225	8349509..8349763	-	255	WP_161855581.1	hypothetical protein	-
ACH79_RS39230	8350057..8350614	+	558	WP_161855582.1	hypothetical protein	-
ACH79_RS39235	8350611..8351075	+	465	WP_161855583.1	hypothetical protein	-
ACH79_RS39240	8351159..8352364	+	1206	WP_161855584.1	hypothetical protein	-
ACH79_RS39245	8352369..8352952	+	584	Protein_7838	phage terminase large subunit family protein	-
ACH79_RS39250	8352961..8353494	-	534	WP_161855585.1	GNAT family N-acetyltransferase	Toxin
ACH79_RS39255	8353482..8353799	-	318	WP_161855586.1	DUF1778 domain-containing protein	Antitoxin
ACH79_RS39260	8354494..8354970	+	477	WP_161855587.1	hypothetical protein	-
ACH79_RS39265	8355108..8355248	-	141	WP_161855588.1	hypothetical protein	-
ACH79_RS39270	8355500..8356063	+	564	WP_161855589.1	hypothetical protein	-
ACH79_RS39275	8357194..8357559	+	366	WP_161855590.1	response regulator	-
ACH79_RS39280	8357670..8358068	+	399	WP_161855591.1	recombinase family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	8346258..8357559	11301

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Vibrio phage ICP1, Orf50 (16-104)

Sequences

Toxin

Protein

• Length: 178 a.a.
• Molecular weight: 19886.82 Da
• Isoelectric Point: 7.7496

>T78674 WP_161855585.1 NZ_CP022222:c8353494-8352961 [Bradyrhizobium sp. CCBAU 051011]
VAEIVEHPRQARGELTRPVRLTTFHDLGHFDCGKPPLNDWIKNQALNSEGQFARTYVVCSGNVVVGYYCIAMGSVERKQL
PSKLKRKQGLPNHAPVAIIGRLARDKSPQWKGLGKDLLQDALIRIVSVSENIGVRCVLVHAIDDEAAQFWKDQEFQEYPD
GSRTFFMPIETVIEAMS

Nucleotide

• Length: 534 bp

>T78674 NZ_CP022222:c8353494-8352961 [Bradyrhizobium sp. CCBAU 051011]
GTGGCAGAAATAGTCGAGCATCCTCGTCAAGCGCGCGGCGAACTCACTCGCCCCGTGCGCTTGACGACTTTCCACGATCT
CGGCCATTTTGATTGCGGAAAGCCGCCGCTTAATGATTGGATCAAAAATCAAGCGCTGAATAGCGAGGGGCAATTCGCCC
GAACTTACGTGGTATGTAGTGGCAATGTGGTCGTAGGCTATTACTGCATTGCTATGGGCAGCGTTGAACGCAAACAATTA
CCGTCCAAGCTGAAGCGCAAGCAAGGTCTCCCCAATCACGCACCTGTCGCCATTATCGGCCGACTGGCTCGTGACAAATC
GCCCCAATGGAAGGGCTTGGGCAAGGACCTCTTGCAGGACGCGCTGATACGGATTGTTTCCGTTTCGGAAAACATCGGAG
TTCGTTGCGTTCTTGTTCACGCGATCGACGACGAGGCAGCGCAGTTTTGGAAAGATCAGGAATTCCAGGAGTATCCTGAC
GGTTCGCGAACGTTTTTTATGCCAATTGAAACTGTAATCGAGGCCATGTCTTAG

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11584.42 Da
• Isoelectric Point: 10.6093

>AT78674 WP_161855586.1 NZ_CP022222:c8353799-8353482 [Bradyrhizobium sp. CCBAU 051011]
MSTAVLERPPARSKGRVQKSSANIHIRAPQQTKQLIDTAAAAVGKTLSEFVLDSARQHAIDVLLDQRLFVLDAEKYDAFI
DALDNPPPAGPALKALMKRRPLWQK

Nucleotide

• Length: 318 bp

>AT78674 NZ_CP022222:c8353799-8353482 [Bradyrhizobium sp. CCBAU 051011]
ATGTCAACCGCAGTATTAGAGCGCCCGCCCGCGCGTTCGAAGGGGCGGGTCCAGAAAAGTAGCGCGAACATTCACATTCG
CGCTCCGCAGCAGACTAAGCAGCTCATAGACACCGCCGCTGCTGCTGTTGGCAAGACATTGAGTGAATTCGTGCTTGATA
GCGCGCGACAGCACGCCATCGATGTTCTGCTCGACCAGCGTCTATTTGTTCTAGACGCGGAAAAGTATGATGCATTCATC
GATGCTCTCGACAATCCGCCGCCTGCCGGACCTGCGCTCAAGGCGCTGATGAAGCGTCGACCGCTGTGGCAGAAATAG