Detailed information of TA system TA078670

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/Tad-HTH_37
• Location: 584500..585209
• Replicon: chromosome
• Accession: NZ_CP022222
• Organism: Bradyrhizobium sp. CCBAU 051011

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: ACH79_RS02810
• Protein ID: WP_161849663.1
• Coordinates: 584500..584871 (+)
• Length: 124 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: ACH79_RS02815
• Protein ID: WP_202639167.1
• Coordinates: 584868..585209 (+)
• Length: 114 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
ACH79_RS02790	579592..580170	-	579	WP_161856178.1	hypothetical protein	-
ACH79_RS02795	580305..581138	-	834	WP_161849660.1	shikimate dehydrogenase	-
ACH79_RS02800	581273..583321	-	2049	WP_161849661.1	elongation factor G	-
ACH79_RS02805	583738..584220	-	483	WP_161849662.1	DUF992 domain-containing protein	-
ACH79_RS02810	584500..584871	+	372	WP_161849663.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
ACH79_RS02815	584868..585209	+	342	WP_202639167.1	helix-turn-helix domain-containing protein	Antitoxin
ACH79_RS02820	585283..585798	-	516	WP_161849665.1	DUF992 domain-containing protein	-
ACH79_RS02825	586032..587234	-	1203	WP_161849666.1	pyridoxal phosphate-dependent aminotransferase	-
ACH79_RS02830	587425..588678	+	1254	WP_161849667.1	DUF2029 domain-containing protein	-
ACH79_RS02835	588880..589533	+	654	WP_161856179.1	glutathione S-transferase family protein	-
ACH79_RS42840	589717..589893	+	177	WP_202639168.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (19-109)

Antitoxin

• Cro/C1-type helix-turn-helix domain (38-92)

Sequences

Toxin

Protein

• Length: 124 a.a.
• Molecular weight: 13612.71 Da
• Isoelectric Point: 10.8435

>T78670 WP_161849663.1 NZ_CP022222:584500-584871 [Bradyrhizobium sp. CCBAU 051011]
VKDLLRAIKPAIFVGSSRKDLQGFPAAIRSGIGQALFEAQIGEHPHNAKPLKGLSGVLEIRDNFDGDTYRAVYTVRLEGV
LYVLHAFQKKSTSGIATPQRHMDLIRQRLRDAEAIHKAARGVR

Nucleotide

• Length: 372 bp

>T78670 NZ_CP022222:584500-584871 [Bradyrhizobium sp. CCBAU 051011]
GTGAAAGATCTGCTCCGCGCTATTAAGCCTGCGATTTTTGTGGGCTCCAGCCGAAAGGACCTGCAAGGATTTCCAGCGGC
CATCCGCAGCGGGATCGGGCAAGCTCTTTTCGAAGCGCAGATCGGGGAGCATCCACACAACGCCAAGCCTCTGAAGGGTT
TGAGCGGAGTGTTGGAGATTCGCGACAATTTTGATGGCGATACCTATCGCGCCGTCTACACGGTGCGTCTTGAGGGTGTC
CTGTACGTCCTGCACGCCTTCCAAAAAAAATCCACCAGTGGGATAGCCACCCCTCAGCGACACATGGATCTGATACGCCA
GCGCCTGCGCGACGCCGAAGCCATTCACAAAGCAGCCAGGGGAGTTCGATGA

Antitoxin

Protein

• Length: 114 a.a.
• Molecular weight: 12456.81 Da
• Isoelectric Point: 11.2756

>AT78670 WP_202639167.1 NZ_CP022222:584868-585209 [Bradyrhizobium sp. CCBAU 051011]
MMSAKKLPAHEVGSGNIFADLGLPNAEEHQLKAALVVQLKRLIAERGLTQVAAAKLVGMKQPDLSKLLRGQFRLVSVEKL
MRMLTAFDQDVEITLKPHRKRGTAGRITFIRAA

Nucleotide

• Length: 342 bp

>AT78670 NZ_CP022222:584868-585209 [Bradyrhizobium sp. CCBAU 051011]
ATGATGAGCGCCAAAAAACTGCCCGCCCATGAAGTTGGAAGCGGCAATATCTTCGCTGATCTTGGTTTACCTAATGCAGA
GGAGCACCAACTCAAGGCTGCACTGGTGGTGCAGTTGAAGCGACTGATCGCCGAACGTGGTCTCACCCAGGTCGCGGCGG
CCAAGCTGGTAGGGATGAAACAGCCCGACCTCTCGAAGCTGCTGCGCGGCCAGTTCCGGCTGGTGTCCGTGGAAAAGCTG
ATGCGGATGCTCACCGCCTTCGATCAGGATGTGGAGATTACCTTGAAGCCGCATCGCAAACGCGGCACGGCCGGCCGGAT
CACCTTCATTCGGGCCGCGTAG