Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/Tad-HTH_37
Location 584500..585209 Replicon chromosome
Accession NZ_CP022222
Organism Bradyrhizobium sp. CCBAU 051011

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag ACH79_RS02810 Protein ID WP_161849663.1
Coordinates 584500..584871 (+) Length 124 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag ACH79_RS02815 Protein ID WP_202639167.1
Coordinates 584868..585209 (+) Length 114 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
ACH79_RS02790 579592..580170 - 579 WP_161856178.1 hypothetical protein -
ACH79_RS02795 580305..581138 - 834 WP_161849660.1 shikimate dehydrogenase -
ACH79_RS02800 581273..583321 - 2049 WP_161849661.1 elongation factor G -
ACH79_RS02805 583738..584220 - 483 WP_161849662.1 DUF992 domain-containing protein -
ACH79_RS02810 584500..584871 + 372 WP_161849663.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
ACH79_RS02815 584868..585209 + 342 WP_202639167.1 helix-turn-helix domain-containing protein Antitoxin
ACH79_RS02820 585283..585798 - 516 WP_161849665.1 DUF992 domain-containing protein -
ACH79_RS02825 586032..587234 - 1203 WP_161849666.1 pyridoxal phosphate-dependent aminotransferase -
ACH79_RS02830 587425..588678 + 1254 WP_161849667.1 DUF2029 domain-containing protein -
ACH79_RS02835 588880..589533 + 654 WP_161856179.1 glutathione S-transferase family protein -
ACH79_RS42840 589717..589893 + 177 WP_202639168.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(19-109)

Antitoxin

Cro/C1-type helix-turn-helix domain

(38-92)


Sequences

Toxin        


Download         Length: 124 a.a.        Molecular weight: 13612.71 Da        Isoelectric Point: 10.8435

>T78670 WP_161849663.1 NZ_CP022222:584500-584871 [Bradyrhizobium sp. CCBAU 051011]
VKDLLRAIKPAIFVGSSRKDLQGFPAAIRSGIGQALFEAQIGEHPHNAKPLKGLSGVLEIRDNFDGDTYRAVYTVRLEGV
LYVLHAFQKKSTSGIATPQRHMDLIRQRLRDAEAIHKAARGVR

Download         Length: 372 bp

>T78670 NZ_CP022222:584500-584871 [Bradyrhizobium sp. CCBAU 051011]
GTGAAAGATCTGCTCCGCGCTATTAAGCCTGCGATTTTTGTGGGCTCCAGCCGAAAGGACCTGCAAGGATTTCCAGCGGC
CATCCGCAGCGGGATCGGGCAAGCTCTTTTCGAAGCGCAGATCGGGGAGCATCCACACAACGCCAAGCCTCTGAAGGGTT
TGAGCGGAGTGTTGGAGATTCGCGACAATTTTGATGGCGATACCTATCGCGCCGTCTACACGGTGCGTCTTGAGGGTGTC
CTGTACGTCCTGCACGCCTTCCAAAAAAAATCCACCAGTGGGATAGCCACCCCTCAGCGACACATGGATCTGATACGCCA
GCGCCTGCGCGACGCCGAAGCCATTCACAAAGCAGCCAGGGGAGTTCGATGA

Antitoxin


Download         Length: 114 a.a.        Molecular weight: 12456.81 Da        Isoelectric Point: 11.2756

>AT78670 WP_202639167.1 NZ_CP022222:584868-585209 [Bradyrhizobium sp. CCBAU 051011]
MMSAKKLPAHEVGSGNIFADLGLPNAEEHQLKAALVVQLKRLIAERGLTQVAAAKLVGMKQPDLSKLLRGQFRLVSVEKL
MRMLTAFDQDVEITLKPHRKRGTAGRITFIRAA

Download         Length: 342 bp

>AT78670 NZ_CP022222:584868-585209 [Bradyrhizobium sp. CCBAU 051011]
ATGATGAGCGCCAAAAAACTGCCCGCCCATGAAGTTGGAAGCGGCAATATCTTCGCTGATCTTGGTTTACCTAATGCAGA
GGAGCACCAACTCAAGGCTGCACTGGTGGTGCAGTTGAAGCGACTGATCGCCGAACGTGGTCTCACCCAGGTCGCGGCGG
CCAAGCTGGTAGGGATGAAACAGCCCGACCTCTCGAAGCTGCTGCGCGGCCAGTTCCGGCTGGTGTCCGTGGAAAAGCTG
ATGCGGATGCTCACCGCCTTCGATCAGGATGTGGAGATTACCTTGAAGCCGCATCGCAAACGCGGCACGGCCGGCCGGAT
CACCTTCATTCGGGCCGCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References