Detailed information of TA system TA078669

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 1948798..1950332
• Replicon: chromosome
• Accession: NZ_CP022221
• Organism: Bradyrhizobium zhanjiangense strain CCBAU 51778

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: -
• Locus tag: XH85_RS09360
• Protein ID: WP_128931672.1
• Coordinates: 1948798..1949721 (-)
• Length: 308 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: -
• Locus tag: XH85_RS09365
• Protein ID: WP_128937171.1
• Coordinates: 1949718..1950332 (-)
• Length: 205 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
XH85_RS09340	1943930..1944859	-	930	WP_128931669.1	hypothetical protein	-
XH85_RS09345	1944963..1946708	-	1746	WP_128931670.1	ATP-binding protein	-
XH85_RS09350	1946705..1947742	-	1038	WP_128931671.1	SIR2 family protein	-
XH85_RS09355	1947963..1948314	-	352	Protein_1815	hypothetical protein	-
XH85_RS09360	1948798..1949721	-	924	WP_128931672.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
XH85_RS09365	1949718..1950332	-	615	WP_128937171.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	Antitoxin
XH85_RS09370	1950423..1954481	+	4059	WP_208758143.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Integrative and Conjugative Element	-	-	1918087..2063054	144967

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (39-273)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (14-55)

Sequences

Toxin

Protein

• Length: 308 a.a.
• Molecular weight: 34507.83 Da
• Isoelectric Point: 5.7390

>T78669 WP_128931672.1 NZ_CP022221:c1949721-1948798 [Bradyrhizobium zhanjiangense]
MMAKALKNPAASIRQRLLQHTKQHGDDYQRILTRYAIERLLFRLSQTEAAERYMLKGAMLFVTWPEHVFRPTGDLDLLGQ
GDPEPAIIIELFTRICQVEAPDDGIVFDPATLKVEPVRETDKYQGVQLSLKGELAKAMIHVQIDIGFGDHVYPPPTRRTF
PNLLPDLPAASILMYPPETVVAEKFEAMIRFGVTNGRIKDFYDVWVTLRTFAFDLPELVEAVGGTLRRRETAIPTEMPVG
LTEAFATIAEERGLWSGFLRRNPPSIQPPAFADLQVELQRFFGPVIAGLALPEGAKGRWDPDGGAWR

Nucleotide

• Length: 924 bp

>T78669 NZ_CP022221:c1949721-1948798 [Bradyrhizobium zhanjiangense]
ATGATGGCCAAGGCTCTCAAGAATCCTGCGGCCTCAATCAGGCAGCGACTGCTTCAACACACTAAACAGCATGGCGACGA
CTATCAGCGCATCCTGACGCGCTACGCGATCGAGCGCCTGCTCTTCCGCCTCAGCCAGACGGAAGCCGCCGAGCGCTATA
TGCTCAAGGGCGCCATGTTGTTCGTAACGTGGCCCGAACATGTCTTTAGGCCGACCGGCGACCTCGACTTGCTCGGCCAG
GGCGACCCCGAGCCCGCCATTATCATCGAGCTGTTCACTCGCATCTGCCAGGTCGAAGCCCCAGACGACGGAATCGTGTT
CGATCCGGCCACTCTGAAGGTCGAGCCGGTGCGTGAAACTGACAAGTATCAGGGCGTCCAGTTGAGCCTAAAGGGCGAGC
TGGCCAAGGCGATGATCCATGTTCAGATCGACATTGGCTTCGGCGATCACGTCTACCCGCCGCCGACGCGCCGGACCTTC
CCGAACCTGTTGCCGGACCTGCCGGCAGCGAGCATCCTGATGTACCCGCCGGAGACCGTGGTCGCCGAGAAGTTCGAGGC
GATGATCCGCTTCGGGGTGACGAATGGAAGGATCAAGGATTTTTACGATGTATGGGTCACGCTCCGGACCTTTGCATTCG
ACTTGCCAGAACTGGTGGAAGCCGTCGGCGGAACGCTCCGGCGCCGAGAGACCGCGATTCCGACCGAGATGCCTGTGGGC
TTGACCGAGGCGTTCGCGACCATCGCCGAAGAACGCGGTCTATGGAGTGGCTTCCTTCGCCGAAATCCGCCGTCCATCCA
GCCGCCGGCTTTCGCAGACCTTCAAGTGGAGCTGCAGCGCTTCTTCGGTCCCGTGATCGCCGGCCTCGCCTTGCCGGAAG
GCGCCAAGGGCAGATGGGACCCGGATGGCGGAGCCTGGCGCTAA

Antitoxin

Protein

• Length: 205 a.a.
• Molecular weight: 22847.37 Da
• Isoelectric Point: 10.1930

>AT78669 WP_128937171.1 NZ_CP022221:c1950332-1949718 [Bradyrhizobium zhanjiangense]
MVERHTNYRESALRLIRDRGIARARDFKAAGIPLVYLKRLADAGDIVRLGRGLYQDAERVGEDAAHNLAEAARLVPNGVV
SLVSALRHHELTTQLPHAVWMTIPHKARTPNVQGLRLEIVRATGEVLTSGVEHVRVEGVDVPIYGVAKTIADCFKHRRHV
GEDVAIEALRDALRQRKTTASELMKYATINRVVERIEPYIKAMQ

Nucleotide

• Length: 615 bp

>AT78669 NZ_CP022221:c1950332-1949718 [Bradyrhizobium zhanjiangense]
ATGGTAGAACGTCATACGAATTATCGCGAGAGCGCCCTTCGTCTCATCCGAGACCGAGGAATTGCGCGCGCGCGCGATTT
CAAGGCCGCGGGCATCCCGCTGGTCTATCTGAAGCGCCTTGCCGACGCCGGCGACATCGTCCGCCTCGGCCGCGGCCTCT
ATCAAGATGCTGAGCGAGTCGGCGAAGACGCCGCTCACAATCTGGCCGAAGCCGCGCGGCTCGTGCCAAATGGAGTCGTC
AGCCTCGTCAGCGCGCTTCGCCACCATGAGTTGACTACCCAGCTGCCGCACGCTGTTTGGATGACCATACCCCACAAGGC
CCGGACGCCGAACGTGCAAGGCCTACGGCTCGAGATCGTCCGGGCGACGGGCGAGGTCCTGACGTCGGGCGTCGAGCACG
TCCGGGTAGAAGGAGTCGACGTGCCGATCTACGGGGTCGCGAAGACGATCGCCGATTGCTTCAAACATCGCCGCCACGTT
GGCGAGGACGTTGCCATAGAGGCGCTCCGAGACGCCCTACGGCAACGGAAGACCACAGCGAGCGAGCTCATGAAATACGC
GACAATCAACCGGGTCGTTGAGCGGATCGAGCCCTACATCAAGGCAATGCAATGA