Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 688092..688723 Replicon chromosome
Accession NZ_CP022221
Organism Bradyrhizobium zhanjiangense strain CCBAU 51778

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag XH85_RS03330 Protein ID WP_091897895.1
Coordinates 688319..688723 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag XH85_RS03325 Protein ID WP_091897901.1
Coordinates 688092..688322 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
XH85_RS03300 683123..684190 + 1068 WP_128930724.1 LysM peptidoglycan-binding domain-containing protein -
XH85_RS03305 684270..684575 - 306 Protein_636 transposase -
XH85_RS03310 684852..685370 - 519 WP_128930725.1 hypothetical protein -
XH85_RS03315 685755..687023 + 1269 WP_128937079.1 Spy/CpxP family protein refolding chaperone -
XH85_RS03320 687024..687890 - 867 WP_128930726.1 hypothetical protein -
XH85_RS03325 688092..688322 + 231 WP_091897901.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
XH85_RS03330 688319..688723 + 405 WP_091897895.1 PIN domain-containing protein Toxin
XH85_RS03335 688894..691341 - 2448 WP_128930727.1 HAMP domain-containing protein -
XH85_RS03340 691549..693600 - 2052 WP_128930728.1 AsmA family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 684255..684494 239


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-114)

Antitoxin

SpoVT-AbrB domain

(5-36)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14420.43 Da        Isoelectric Point: 6.8679

>T78667 WP_091897895.1 NZ_CP022221:688319-688723 [Bradyrhizobium zhanjiangense]
VSAFFDSNILIYAYSTDTKRQRALNTIAGGGVISAQVLNEFTNVLRKKQKQDWPMIEAAVQSLRFRFPDILPLTSHTHAA
ALALASGHTLAFYDALIVAAAVEAGCDTLYSEDLQHGRSIGGLTIVNPFLGSAP

Download         Length: 405 bp

>T78667 NZ_CP022221:688319-688723 [Bradyrhizobium zhanjiangense]
GTGAGCGCCTTCTTCGACAGCAATATTCTGATCTACGCCTATTCGACCGACACAAAGCGCCAGCGAGCGCTGAACACGAT
TGCTGGCGGTGGTGTCATCAGCGCGCAGGTGCTCAACGAGTTCACCAACGTGTTGCGTAAGAAGCAGAAGCAGGATTGGC
CAATGATCGAGGCAGCTGTGCAGTCCCTCCGCTTTCGCTTTCCCGACATCTTGCCGCTGACATCACACACGCACGCCGCG
GCGCTTGCGCTTGCCAGCGGTCACACCCTTGCCTTTTATGATGCGCTGATCGTCGCTGCGGCGGTCGAGGCCGGCTGCGA
CACGCTCTACAGCGAAGACCTGCAACACGGCCGCAGCATCGGCGGGCTCACCATCGTCAATCCGTTTCTCGGGAGCGCAC
CGTGA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8625.83 Da        Isoelectric Point: 5.1369

>AT78667 WP_091897901.1 NZ_CP022221:688092-688322 [Bradyrhizobium zhanjiangense]
VLVSKWGNSLAVRLPKALVEALNLSPGDELNVVEASKGRLAVEKIDKRAEFLRQVEQFQFPLPEGYKFDRDEANER

Download         Length: 231 bp

>AT78667 NZ_CP022221:688092-688322 [Bradyrhizobium zhanjiangense]
GTGCTCGTTTCCAAATGGGGAAATAGCTTGGCGGTTCGCCTGCCCAAGGCGCTTGTCGAGGCTCTGAATCTTTCGCCCGG
CGACGAGCTCAACGTGGTGGAGGCCTCGAAGGGCCGGCTCGCAGTAGAGAAGATCGACAAGCGAGCGGAATTTCTCAGGC
AGGTGGAGCAGTTCCAGTTTCCCCTGCCCGAAGGCTACAAGTTCGATCGCGATGAGGCGAACGAGCGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References