Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-Phd
Location 1269772..1270475 Replicon chromosome
Accession NZ_CP022219
Organism Bradyrhizobium guangxiense strain CCBAU 53363

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag X268_RS05965 Protein ID WP_128924069.1
Coordinates 1269772..1270197 (-) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag X268_RS05970 Protein ID WP_128924070.1
Coordinates 1270194..1270475 (-) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
X268_RS05940 1266566..1266973 + 408 WP_128924064.1 acyl-CoA thioesterase -
X268_RS05945 1267199..1267390 + 192 WP_128924065.1 hypothetical protein -
X268_RS05950 1267532..1267984 - 453 WP_128924066.1 nuclear transport factor 2 family protein -
X268_RS05955 1268128..1268814 + 687 WP_128924067.1 HAD-IA family hydrolase -
X268_RS05960 1268923..1269768 + 846 WP_128924068.1 DeoR/GlpR family DNA-binding transcription regulator -
X268_RS05965 1269772..1270197 - 426 WP_128924069.1 type II toxin-antitoxin system VapC family toxin Toxin
X268_RS05970 1270194..1270475 - 282 WP_128924070.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
X268_RS05975 1270707..1272257 + 1551 WP_128924071.1 glycerol-3-phosphate dehydrogenase -
X268_RS05980 1272254..1273330 + 1077 WP_128924072.1 ABC transporter ATP-binding protein -
X268_RS05985 1273346..1274431 + 1086 WP_128924073.1 ABC transporter ATP-binding protein -
X268_RS05990 1274431..1275333 + 903 WP_128924074.1 sugar ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(14-77)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15377.56 Da        Isoelectric Point: 4.8616

>T78665 WP_128924069.1 NZ_CP022219:c1270197-1269772 [Bradyrhizobium guangxiense]
VNLLLDTNVLSEVQRSTPSPNVLAWLDTIDEDRAFICVASIAELRRGVALLEDGRRRTALAAWLAHDLPARFAGRVLPID
HAVAERWGDLMAQSHRSGVALSVMDGFFAATALVNDLTLVTRNVKDFAAFGVALLNPWDDA

Download         Length: 426 bp

>T78665 NZ_CP022219:c1270197-1269772 [Bradyrhizobium guangxiense]
GTGAATCTTCTGCTCGACACCAACGTGCTGTCGGAAGTTCAGCGGTCCACGCCTTCGCCGAACGTCCTGGCGTGGCTGGA
TACGATCGATGAGGACCGTGCGTTCATCTGCGTTGCATCGATTGCCGAGCTTCGCCGCGGCGTCGCCTTGCTGGAGGACG
GGCGCCGGCGCACCGCGCTGGCCGCCTGGCTTGCCCACGATCTGCCGGCACGGTTTGCCGGACGCGTCCTGCCGATCGAT
CACGCGGTGGCCGAGCGCTGGGGTGACCTCATGGCACAGAGCCATAGGAGCGGCGTCGCGTTGTCCGTCATGGATGGCTT
CTTTGCGGCGACTGCGCTCGTCAACGATCTCACGCTCGTCACACGCAACGTGAAGGATTTTGCGGCCTTCGGCGTCGCGC
TGCTCAACCCGTGGGACGACGCTTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10278.54 Da        Isoelectric Point: 5.1570

>AT78665 WP_128924070.1 NZ_CP022219:c1270475-1270194 [Bradyrhizobium guangxiense]
MADRNTAPDALPDDTWTLANAKARLSEVIDRAENGPQIITRHGKPSAVVVSAEEWARKTARKGTLAEFLLASPLRGADVE
LERMHDTPRDEMQ

Download         Length: 282 bp

>AT78665 NZ_CP022219:c1270475-1270194 [Bradyrhizobium guangxiense]
ATGGCCGATCGAAACACTGCACCGGACGCGCTTCCTGATGACACTTGGACGCTCGCCAACGCCAAGGCGCGACTGTCGGA
GGTGATCGACCGTGCCGAAAACGGCCCGCAGATCATCACCCGACACGGCAAGCCCAGCGCAGTCGTCGTTTCCGCCGAGG
AATGGGCCCGCAAGACCGCGCGCAAGGGCACGCTCGCGGAATTCCTGCTGGCCTCACCGCTGCGTGGTGCCGACGTTGAA
CTTGAGCGCATGCACGACACGCCACGCGACGAGATGCAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References