Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 3884939..3886782 Replicon chromosome
Accession NZ_CP022210
Organism Burkholderia gladioli pv. gladioli strain FDAARGOS_188

Toxin (Protein)


Gene name doc Uniprot ID A0A808W4K9
Locus tag A8H28_RS16745 Protein ID WP_036057353.1
Coordinates 3885817..3886782 (-) Length 322 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag A8H28_RS16740 Protein ID WP_042285493.1
Coordinates 3884939..3885799 (-) Length 287 a.a.

Genomic Context

A8H28_RS16775A8H28_RS16720A8H28_RS16725A8H28_RS16730A8H28_RS16735A8H28_RS16740A8H28_RS16745A8H28_RS16750A8H28_RS16755A8H28_RS16760A8H28_RS16765A8H28_RS16770
Location: 3890395..3891474 (1080 bp)
Type: Others
Protein ID: WP_017921239.1
Location: 3880086..3881576 (1491 bp)
Type: Others
Protein ID: WP_036056695.1
Location: 3881653..3882486 (834 bp)
Type: Others
Protein ID: WP_036056696.1
Location: 3882479..3884152 (1674 bp)
Type: Others
Protein ID: WP_036056697.1
Location: 3884145..3884942 (798 bp)
Type: Others
Protein ID: WP_013689909.1
Location: 3884939..3885799 (861 bp)
Type: Antitoxin
Protein ID: WP_042285493.1
Location: 3885817..3886782 (966 bp)
Type: Toxin
Protein ID: WP_036057353.1
Location: 3886809..3887336 (528 bp)
Type: Others
Protein ID: WP_036038832.1
Location: 3887435..3888205 (771 bp)
Type: Others
Protein ID: WP_036056699.1
Location: 3888198..3889307 (1110 bp)
Type: Others
Protein ID: WP_025097964.1
Location: 3889349..3889660 (312 bp)
Type: Others
Protein ID: WP_025097963.1
Location: 3889663..3889980 (318 bp)
Type: Others
Protein ID: WP_013689902.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A8H28_RS167203880086..3881576-1491WP_036056695.1aldehyde dehydrogenase-
A8H28_RS167253881653..3882486-834WP_036056696.1aspartate dehydrogenase-
A8H28_RS167303882479..3884152-1674WP_036056697.1thiamine pyrophosphate-binding protein-
A8H28_RS167353884145..3884942-798WP_013689909.1SDR family oxidoreductase-
A8H28_RS167403884939..3885799-861WP_042285493.1IclR family transcriptional regulatorAntitoxin
A8H28_RS167453885817..3886782-966WP_036057353.1alpha/beta fold hydrolaseToxin
A8H28_RS167503886809..3887336-528WP_036038832.1cupin domain-containing protein-
A8H28_RS167553887435..3888205-771WP_036056699.1SDR family oxidoreductase-
A8H28_RS167603888198..3889307-1110WP_025097964.1aromatic ring-hydroxylating dioxygenase subunit alpha-
A8H28_RS167653889349..3889660-312WP_025097963.1hypothetical protein-
A8H28_RS167703889663..3889980-318WP_013689902.1non-heme iron oxygenase ferredoxin subunit-
A8H28_RS167753890395..3891474+1080WP_017921239.1porin-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(66-304)

Antitoxin

Transcription regulator IclR, N-terminal

(25-73)


Sequences

Toxin        


Download         Length: 322 a.a.        Molecular weight: 32867.37 Da        Isoelectric Point: 7.3751

>T78653 WP_036057353.1 NZ_CP022210:c3886782-3885817 [Burkholderia gladioli pv. gladioli]
MSEIDPRGAEAEAGPDAALAARLWQFPARRIAIREAGLIGWRESGPAQGAGDSTARAAAGERALPVVLLHGIGSGAASWL
AQLDTLGASRRVLAWDAPGYGESTPVAPASPLAADYAASLAGWLDALAIERCVLVGHSLGAIVAGAFARRHAGRLAGLLL
VSPAAGYGAAPAATRDERRDARLAMLAALGPAGLAEQRSANMLSAHAGEAARAWVRRVMAQVKPAGYTQATHLLANADLA
ADLAAWRAMTDAAGAARVEVMVGAEDGITPPNACERIAAAAGVALRIVPRAGHAGYVEAPERYSALIGAFCARCDESWRQ
A

Download         Length: 966 bp

>T78653 NZ_CP022210:c3886782-3885817 [Burkholderia gladioli pv. gladioli]
ATGAGCGAAATCGATCCGCGCGGGGCCGAGGCAGAGGCTGGGCCCGACGCGGCCCTGGCCGCCCGACTCTGGCAGTTTCC
GGCGCGGCGCATCGCCATTCGCGAAGCCGGGCTGATCGGCTGGCGCGAATCGGGTCCAGCGCAGGGGGCCGGCGATTCGA
CGGCACGCGCGGCCGCTGGCGAGCGGGCATTGCCGGTGGTGCTGCTGCACGGCATCGGCTCGGGCGCGGCCTCGTGGCTG
GCCCAGCTCGACACGCTCGGCGCGTCGCGTCGCGTGCTGGCCTGGGACGCGCCCGGTTATGGCGAATCGACGCCGGTCGC
GCCGGCCTCGCCGCTGGCGGCCGATTACGCGGCGTCGCTGGCCGGCTGGCTCGACGCGCTCGCCATCGAGCGCTGCGTGC
TGGTGGGGCACTCGCTCGGCGCGATCGTGGCCGGCGCCTTCGCGCGCCGGCATGCCGGGCGGCTGGCCGGCTTGCTGCTG
GTTTCGCCGGCCGCCGGCTACGGCGCGGCACCGGCCGCCACGCGCGACGAACGGCGCGATGCGCGGCTCGCGATGCTGGC
CGCGCTCGGGCCCGCGGGCCTGGCCGAACAACGCAGCGCCAACATGCTGTCGGCGCATGCCGGCGAGGCCGCCCGCGCCT
GGGTGCGCCGCGTGATGGCGCAGGTGAAGCCGGCCGGCTACACGCAGGCCACCCACCTGCTCGCGAACGCCGACCTGGCC
GCCGATCTCGCCGCCTGGCGGGCGATGACCGACGCCGCCGGTGCCGCGCGCGTGGAGGTGATGGTGGGCGCCGAGGACGG
CATCACGCCGCCGAACGCCTGCGAACGGATCGCGGCGGCGGCCGGCGTGGCGCTGCGTATCGTGCCGCGCGCCGGCCATG
CCGGCTACGTGGAGGCACCCGAGCGCTACTCGGCGCTGATCGGCGCGTTCTGCGCGCGCTGCGACGAATCATGGAGACAG
GCATGA

Antitoxin


Download         Length: 287 a.a.        Molecular weight: 31033.35 Da        Isoelectric Point: 6.5132

>AT78653 WP_042285493.1 NZ_CP022210:c3885799-3884939 [Burkholderia gladioli pv. gladioli]
MRSEPADSGAPEADAANGAYVVPGLERGLRILAEFSPREPVLGAPELSKRLGIPRTTVFRLLQTLESLGFLERADKDRNY
RLGVAVLRLGFEYLSSLELTDLGLPVIEGLREATGFTTHIVIRDGRDVVFVAKAQSAAPAFSSIRVNVGTRLPAHATTHG
HVLMGDLSEAELRALYPERQLERATRATPDSLEALLALVREDAARGYGISNASFERGISVVTAPVRNDTQRIVAAVTVTV
PKPEIDAALIADGLVEKVVRAANELSRRLNYRSDDENSYLKALGLR

Download         Length: 861 bp

>AT78653 NZ_CP022210:c3885799-3884939 [Burkholderia gladioli pv. gladioli]
CTGCGAAGCGAGCCGGCCGACAGCGGCGCGCCCGAGGCGGATGCCGCGAACGGCGCCTACGTGGTACCTGGCCTCGAACG
CGGGCTGCGGATCCTCGCGGAATTCTCGCCGCGCGAGCCGGTGCTGGGCGCGCCGGAATTGTCGAAGCGGCTCGGCATTC
CGCGCACCACGGTGTTCCGGCTGCTGCAGACGCTCGAATCGCTGGGCTTCCTGGAGCGCGCCGACAAGGACCGCAATTAC
CGGCTCGGCGTGGCGGTGCTGCGCCTGGGCTTCGAATACTTGAGCTCGCTGGAGCTGACCGACCTGGGCCTGCCGGTGAT
CGAGGGCCTGCGCGAGGCGACCGGCTTCACCACCCATATCGTGATCCGCGACGGGCGCGACGTGGTGTTCGTCGCCAAGG
CGCAGAGCGCGGCGCCGGCCTTCAGCTCGATTCGCGTCAACGTCGGCACGCGGCTGCCCGCGCATGCCACTACCCACGGC
CACGTGCTGATGGGCGACCTGAGCGAGGCCGAGCTGCGCGCACTGTACCCCGAGCGCCAGCTCGAACGGGCCACGCGTGC
CACGCCCGACAGCCTGGAGGCGCTGCTCGCGCTGGTCCGCGAGGATGCCGCGCGCGGCTACGGCATCAGCAACGCCTCGT
TCGAGCGCGGCATCTCGGTGGTCACCGCGCCGGTGCGCAACGACACGCAGCGCATCGTGGCGGCCGTCACGGTGACGGTG
CCGAAACCCGAGATCGACGCGGCGCTGATCGCCGACGGCCTGGTCGAGAAGGTCGTGAGGGCGGCCAATGAACTGTCGCG
GCGGCTCAATTACCGCTCCGATGATGAGAACTCCTATCTGAAGGCATTGGGATTGCGATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBA0A808W4K9

Antitoxin

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Source
ID
Structure
No matching records found

References