Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 847850..848425 Replicon chromosome
Accession NZ_CP022210
Organism Burkholderia gladioli pv. gladioli strain FDAARGOS_188

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag A8H28_RS04220 Protein ID WP_036054553.1
Coordinates 847850..848137 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A560UNM0
Locus tag A8H28_RS04225 Protein ID WP_036030606.1
Coordinates 848141..848425 (+) Length 95 a.a.

Genomic Context

A8H28_RS04205A8H28_RS04215A8H28_RS04220A8H28_RS04225A8H28_RS04245A8H28_RS04200A8H28_RS04210A8H28_RS04230A8H28_RS04235A8H28_RS04240
Location: 845272..846108 (837 bp)
Type: Others
Protein ID: WP_036054549.1
Location: 846779..847717 (939 bp)
Type: Others
Protein ID: WP_036054551.1
Location: 847850..848137 (288 bp)
Type: Toxin
Protein ID: WP_036054553.1
Location: 848141..848425 (285 bp)
Type: Antitoxin
Protein ID: WP_036030606.1
Location: 852044..853327 (1284 bp)
Type: Others
Protein ID: WP_013689299.1
Location: 843966..845027 (1062 bp)
Type: Others
Protein ID: WP_013689307.1
Location: 846152..846622 (471 bp)
Type: Others
Protein ID: WP_013689305.1
Location: 848483..848809 (327 bp)
Type: Others
Protein ID: WP_036054555.1
Location: 848958..850085 (1128 bp)
Type: Others
Protein ID: WP_167547494.1
Location: 850271..851908 (1638 bp)
Type: Others
Protein ID: WP_036054559.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
A8H28_RS04200843966..845027-1062WP_013689307.1selenide, water dikinase SelD-
A8H28_RS04205845272..846108+837WP_036054549.1DMT family transporter-
A8H28_RS04210846152..846622-471WP_013689305.1Lrp/AsnC family transcriptional regulator-
A8H28_RS04215846779..847717+939WP_036054551.12-dehydropantoate 2-reductase-
A8H28_RS04220847850..848137+288WP_036054553.1type II toxin-antitoxin system RelE/ParE family toxinToxin
A8H28_RS04225848141..848425+285WP_036030606.1putative addiction module antidote proteinAntitoxin
A8H28_RS04230848483..848809-327WP_036054555.1hypothetical protein-
A8H28_RS04235848958..850085-1128WP_167547494.1ABC transporter substrate-binding protein-
A8H28_RS04240850271..851908-1638WP_036054559.1PLP-dependent aminotransferase family protein-
A8H28_RS04245852044..853327+1284WP_013689299.14-aminobutyrate--2-oxoglutarate transaminase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(5-94)

Antitoxin

Uncharacterized protein HI1420

(11-89)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10959.72 Da        Isoelectric Point: 10.4966

>T78650 WP_036054553.1 NZ_CP022210:847850-848137 [Burkholderia gladioli pv. gladioli]
MLRSSEFTNWLSSLRDQRGKARIAARLISAQLGNFGEYRVIGEGVREMKVDFGPGYRIYYVRRAEIVYVLLCGGDKSTQK
KDIKRALQMARELKE

Download         Length: 288 bp

>T78650 NZ_CP022210:847850-848137 [Burkholderia gladioli pv. gladioli]
TTGCTGCGCTCCAGTGAATTCACAAACTGGCTTTCCAGCCTGCGTGATCAGCGCGGCAAAGCCCGAATCGCCGCACGCCT
GATCAGTGCCCAGCTAGGCAATTTTGGCGAGTACCGCGTGATAGGCGAAGGCGTCCGCGAAATGAAGGTCGACTTCGGGC
CGGGTTATCGCATCTACTATGTCCGTCGCGCCGAGATCGTCTATGTCCTTCTCTGCGGTGGCGATAAATCTACACAGAAA
AAAGACATCAAGCGCGCGCTCCAGATGGCGCGCGAACTGAAGGAGTAA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10072.47 Da        Isoelectric Point: 5.0484

>AT78650 WP_036030606.1 NZ_CP022210:848141-848425 [Burkholderia gladioli pv. gladioli]
MPDYAEFDAADYLDNDETVAEFLAVAAEDPDPAVFLAAVAAVARARGMTKVASEAGLGRVTLHKALTPGAHPRYETVQKI
LRSLGLRMTFTVAH

Download         Length: 285 bp

>AT78650 NZ_CP022210:848141-848425 [Burkholderia gladioli pv. gladioli]
ATGCCCGATTACGCCGAATTCGATGCGGCCGACTATCTCGACAATGACGAAACCGTGGCGGAATTTCTCGCGGTTGCGGC
AGAGGATCCCGATCCCGCAGTGTTCCTTGCTGCCGTGGCCGCTGTCGCACGCGCGCGCGGGATGACCAAGGTGGCGTCGG
AAGCCGGCCTTGGACGGGTCACCTTGCACAAGGCGCTGACGCCTGGCGCTCACCCTCGATATGAGACCGTGCAGAAGATC
CTGCGCTCGCTGGGCCTTCGCATGACCTTCACCGTCGCCCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBA0A560UNM0

References