Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-YefM
Location 551224..551723 Replicon chromosome
Accession NZ_CP022208
Organism Rhodococcus biphenylivorans strain TG9

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag CEJ39_RS02680 Protein ID WP_019290516.1
Coordinates 551224..551478 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag CEJ39_RS02685 Protein ID WP_019290515.1
Coordinates 551475..551723 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CEJ39_RS02650 546658..547827 - 1170 WP_019290521.1 acyl-CoA dehydrogenase family protein -
CEJ39_RS02655 547930..548556 + 627 WP_006550849.1 TetR family transcriptional regulator -
CEJ39_RS02660 548714..548926 - 213 WP_019290520.1 hypothetical protein -
CEJ39_RS02665 548933..549175 - 243 WP_064256073.1 transposase -
CEJ39_RS02670 549489..550445 - 957 WP_019290518.1 Lsr2 family protein -
CEJ39_RS23885 550602..551123 + 522 WP_019290517.1 hypothetical protein -
CEJ39_RS02680 551224..551478 - 255 WP_019290516.1 Txe/YoeB family addiction module toxin Toxin
CEJ39_RS02685 551475..551723 - 249 WP_019290515.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
CEJ39_RS02690 551759..552088 + 330 WP_082937719.1 hypothetical protein -
CEJ39_RS02695 552294..552530 + 237 WP_019290513.1 hypothetical protein -
CEJ39_RS02700 552556..553350 + 795 WP_019290512.1 LLM class F420-dependent oxidoreductase -
CEJ39_RS02705 553411..554643 + 1233 WP_019290511.1 alpha/beta fold hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-70)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10078.37 Da        Isoelectric Point: 6.7171

>T78648 WP_019290516.1 NZ_CP022208:c551478-551224 [Rhodococcus biphenylivorans]
VNITFTDEAWDDYQFWISTDRKQLERVNELIRDCQRDPYSGIGKPERLRHALSGLWSRRIDKEHRLVYEVIDGALVIIAA
RYHY

Download         Length: 255 bp

>T78648 NZ_CP022208:c551478-551224 [Rhodococcus biphenylivorans]
GTGAACATCACCTTCACCGATGAAGCCTGGGACGACTACCAGTTCTGGATCTCGACCGACAGAAAGCAGCTCGAGCGTGT
CAACGAGCTGATCAGGGATTGCCAACGAGACCCGTACTCGGGGATCGGCAAACCCGAACGGCTCAGACATGCCCTGTCAG
GACTGTGGTCTCGACGTATCGACAAAGAACACCGCCTGGTCTACGAGGTCATCGACGGTGCCCTGGTCATCATCGCCGCC
CGCTACCACTACTGA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9264.55 Da        Isoelectric Point: 6.4661

>AT78648 WP_019290515.1 NZ_CP022208:c551723-551475 [Rhodococcus biphenylivorans]
MAAITATEARKNFFPLLEQVNKDHTPVEIVSKRGNAVLMSKDDYDAMLETSYLMQSPANARRLLASMQRARGGEHTEREL
IE

Download         Length: 249 bp

>AT78648 NZ_CP022208:c551723-551475 [Rhodococcus biphenylivorans]
ATGGCTGCCATCACTGCTACCGAAGCGAGAAAAAACTTCTTTCCGCTGCTCGAACAGGTCAACAAGGACCACACCCCTGT
GGAAATCGTATCCAAGCGGGGCAATGCCGTCCTGATGTCGAAGGATGACTACGACGCCATGCTCGAGACCTCGTACCTGA
TGCAGTCTCCGGCCAACGCCCGACGACTGCTCGCCAGCATGCAGAGAGCTCGCGGAGGTGAACACACCGAAAGGGAACTC
ATCGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References