Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2122673..2122944 Replicon chromosome
Accession NZ_CP022164
Organism Escherichia coli strain M160133

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2122803..2122906 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2122673..2122944 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CE141_RS10735 2119228..2119890 - 663 WP_000944256.1 exodeoxyribonuclease X -
CE141_RS10740 2119914..2120570 - 657 WP_000011663.1 carbon-nitrogen hydrolase family protein -
CE141_RS10745 2120672..2120902 - 231 WP_077516099.1 DNA polymerase III subunit theta -
CE141_RS10750 2121041..2121415 + 375 WP_000168737.1 CopC domain-containing protein YobA -
CE141_RS10755 2121419..2122291 + 873 WP_000879323.1 copper homeostasis membrane protein CopD -
CE141_RS10760 2122304..2122645 + 342 WP_000976472.1 YebY family protein -
- 2122673..2122944 - 272 - - Antitoxin
- 2122803..2122906 + 104 - - Toxin
CE141_RS10765 2123041..2123697 + 657 WP_000812749.1 protein-serine/threonine phosphatase -
CE141_RS10770 2123698..2123889 - 192 WP_001296140.1 YebW family protein -
CE141_RS10775 2123994..2124230 - 237 WP_001295499.1 DUF1480 family protein -
CE141_RS10780 2124348..2125787 - 1440 WP_024175799.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T78602 NZ_CP022164:2122803-2122906 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT78602 NZ_CP022164:c2122944-2122673 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References