Detailed information of TA system TA078542

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacT-ataR/DUF1778(antitoxin)
• Location: 49622..50379
• Replicon: plasmid unnamed1
• Accession: NZ_CP022140
• Organism: Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: A0A241PXX4
• Locus tag: LFZ47_RS24500
• Protein ID: WP_023994162.1
• Coordinates: 49622..50104 (-)
• Length: 161 a.a.

Antitoxin (Protein)

• Gene name: ataR
• Uniprot ID: A0A727Z1I8
• Locus tag: LFZ47_RS24505
• Protein ID: WP_001195098.1
• Coordinates: 50095..50379 (-)
• Length: 95 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LFZ47_RS24480	44940..45950	-	1011	WP_080227760.1	replication initiation protein	-
LFZ47_RS24485	46696..47862	+	1167	WP_023994210.1	plasmid-partitioning protein SopA	-
LFZ47_RS24490	47862..48821	+	960	WP_080227759.1	ParB/RepB/Spo0J family plasmid partition protein	-
LFZ47_RS24495	48878..49306	-	429	Protein_47	transposase	-
LFZ47_RS24500	49622..50104	-	483	WP_023994162.1	GNAT family N-acetyltransferase	Toxin
LFZ47_RS24505	50095..50379	-	285	WP_001195098.1	DUF1778 domain-containing protein	Antitoxin
LFZ47_RS24510	50500..50754	+	255	WP_080227067.1	type II toxin-antitoxin system Phd/YefM family antitoxin	-
LFZ47_RS24520	51014..51884	-	871	Protein_51	transposase	-
LFZ47_RS24525	51980..53559	+	1580	Protein_52	ISL3 family transposase	-
LFZ47_RS25720	53548..54331	+	784	Protein_53	IS3 family transposase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..109681	109681

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Bacterial antitoxin of type II TA system, VapB (3-44)

Sequences

Toxin

Protein

• Length: 161 a.a.
• Molecular weight: 23713.45 Da
• Isoelectric Point: 5.5500

>T78542 WP_023994162.1 NZ_CP022140:c50104-49622 [Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
F

Nucleotide

• Length: 483 bp

>T78542 NZ_CP022140:c50104-49622 [Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K]
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TTT

Antitoxin

Protein

• Length: 95 a.a.
• Molecular weight: 13999.79 Da
• Isoelectric Point: 5.5500

>AT78542 WP_001195098.1 NZ_CP022140:c50379-50095 [Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFF

Nucleotide

• Length: 285 bp

>AT78542 NZ_CP022140:c50379-50095 [Salmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K]
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
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TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT

Structures

Toxin

• AlphaFold DB: A0A241PXX4

Antitoxin

• AlphaFold DB: A0A727Z1I8