Detailed information of TA system TA078540

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 29910..30535
• Replicon: plasmid unnamed2
• Accession: NZ_CP022137
• Organism: Salmonella enterica subsp. diarizonae serovar 65:c:z str. SA20044251

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: LFZ55_RS24810
• Protein ID: WP_058215171.1
• Coordinates: 30137..30535 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: A0A8F2UQ48
• Locus tag: LFZ55_RS24805
• Protein ID: WP_000450263.1
• Coordinates: 29910..30137 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LFZ55_RS24805	29910..30137	+	228	WP_000450263.1	toxin-antitoxin system antitoxin VapB	Antitoxin
LFZ55_RS24810	30137..30535	+	399	WP_058215171.1	tRNA(fMet)-specific endonuclease VapC	Toxin
LFZ55_RS24815	30544..32787	-	2244	WP_088734824.1	type IV conjugative transfer system coupling protein TraD	-
LFZ55_RS24820	33164..33895	-	732	WP_011282396.1	complement resistance protein TraT	-
LFZ55_RS24825	34141..34623	-	483	WP_000787664.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..66457	66457

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (1-124)

Antitoxin

• Antitoxin VapB-like (1-83)

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 17065.17 Da
• Isoelectric Point: 12.9205

>T78540 WP_058215171.1 NZ_CP022137:30137-30535 [Salmonella enterica subsp. diarizonae serovar 65:c:z str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 399 bp

>T78540 NZ_CP022137:30137-30535 [Salmonella enterica subsp. diarizonae serovar 65:c:z str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 9759.25 Da
• Isoelectric Point: 12.6750

>AT78540 WP_000450263.1 NZ_CP022137:29910-30137 [Salmonella enterica subsp. diarizonae serovar 65:c:z str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 228 bp

>AT78540 NZ_CP022137:29910-30137 [Salmonella enterica subsp. diarizonae serovar 65:c:z str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA