Detailed information of TA system TA078539

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vagCD/VapC-VagC
• Location: 3442..4085
• Replicon: plasmid unnamed2
• Accession: NZ_CP022137
• Organism: Salmonella enterica subsp. diarizonae serovar 65:c:z str. SA20044251

Toxin (Protein)

• Gene name: vagD
• Uniprot ID: -
• Locus tag: LFZ55_RS24650
• Protein ID: WP_088734795.1
• Coordinates: 3669..4085 (+)
• Length: 139 a.a.

Antitoxin (Protein)

• Gene name: vagC
• Uniprot ID: -
• Locus tag: LFZ55_RS24645
• Protein ID: WP_088734793.1
• Coordinates: 3442..3672 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LFZ55_RS24620	1..930	+	930	WP_088734789.1	Rpn family recombination-promoting nuclease/putative transposase	-
LFZ55_RS24625	1081..1863	-	783	WP_088734791.1	site-specific integrase	-
LFZ55_RS24635	2172..2477	-	306	WP_001159874.1	type II toxin-antitoxin system toxin CcdB	-
LFZ55_RS24640	2479..2697	-	219	WP_000813642.1	type II toxin-antitoxin system antitoxin CcdA	-
LFZ55_RS24645	3442..3672	+	231	WP_088734793.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
LFZ55_RS24650	3669..4085	+	417	WP_088734795.1	type II toxin-antitoxin system VapC family toxin	Toxin
LFZ55_RS24655	4132..5055	-	924	Protein_6	pcar	-
LFZ55_RS24660	5051..5379	-	329	Protein_7	Tn3 family transposase	-
LFZ55_RS24665	5450..6283	-	834	WP_080071163.1	SdiA-regulated domain-containing protein	-
LFZ55_RS24670	6444..7097	-	654	WP_080071162.1	DsbA family protein	-
LFZ55_RS24675	7355..7693	-	339	WP_080071161.1	helix-turn-helix transcriptional regulator	-
LFZ55_RS24680	7678..7890	-	213	WP_080071160.1	regulator	-
LFZ55_RS24685	8042..8920	-	879	WP_088734797.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..66457	66457

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-120)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 139 a.a.
• Molecular weight: 17834.22 Da
• Isoelectric Point: 12.9398

>T78539 WP_088734795.1 NZ_CP022137:3669-4085 [Salmonella enterica subsp. diarizonae serovar 65:c:z str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 417 bp

>T78539 NZ_CP022137:3669-4085 [Salmonella enterica subsp. diarizonae serovar 65:c:z str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 9887.42 Da
• Isoelectric Point: 12.6808

>AT78539 WP_088734793.1 NZ_CP022137:3442-3672 [Salmonella enterica subsp. diarizonae serovar 65:c:z str.]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 231 bp

>AT78539 NZ_CP022137:3442-3672 [Salmonella enterica subsp. diarizonae serovar 65:c:z str.]
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA