Detailed information of TA system TA078534

Bioinformatically predicted

Overview

TA module

• Type: VII
• Classification (family/domain): HepT-MntA/HepT(toxin)
• Location: 1553572..1554382
• Replicon: chromosome
• Accession: NZ_CP022134
• Organism: Halomonas sp. HG01

Toxin (Protein)

• Gene name: hepT
• Uniprot ID: -
• Locus tag: UN84_RS07365
• Protein ID: WP_046078603.1
• Coordinates: 1553972..1554382 (+)
• Length: 137 a.a.

Antitoxin (Protein)

• Gene name: mntA
• Uniprot ID: -
• Locus tag: UN84_RS07360
• Protein ID: WP_046078602.1
• Coordinates: 1553572..1553982 (+)
• Length: 137 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
UN84_RS07340	1548905..1549669	-	765	WP_046078598.1	UDP-2,3-diacylglucosamine diphosphatase	-
UN84_RS07345	1549747..1550253	-	507	WP_046078599.1	peptidylprolyl isomerase	-
UN84_RS07350	1550406..1552085	+	1680	WP_046078600.1	glutamine--tRNA ligase/YqeY domain fusion protein	-
UN84_RS07355	1552087..1553496	+	1410	WP_046078601.1	cysteine--tRNA ligase	-
UN84_RS07360	1553572..1553982	+	411	WP_046078602.1	nucleotidyltransferase domain-containing protein	Antitoxin
UN84_RS07365	1553972..1554382	+	411	WP_046078603.1	DUF86 domain-containing protein	Toxin
UN84_RS07370	1554449..1554667	-	219	WP_046078604.1	hypothetical protein	-
UN84_RS07375	1555140..1556096	-	957	WP_046078605.1	DUF1853 family protein	-
UN84_RS07380	1556193..1557119	+	927	WP_046078606.1	ABC transporter substrate-binding protein	-
UN84_RS07385	1557116..1558309	+	1194	WP_173834979.1	ABC transporter permease	-
UN84_RS07390	1558306..1559250	+	945	WP_046078609.1	ABC transporter ATP-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease HepT-like (14-131)

Antitoxin

• Polymerase beta, nucleotidyltransferase (17-96)

Sequences

Toxin

Protein

• Length: 137 a.a.
• Molecular weight: 15242.41 Da
• Isoelectric Point: 4.7569

>T78534 WP_046078603.1 NZ_CP022134:1553972-1554382 [Halomonas sp. HG01]
MADDVLLNKAATIERCIGRAREEYDKDPDTFESDQTRQDAAILNLQRACEAAIDAGNRLVRLQQLGLPQSARDVFSLLVQ
ADLLDEALGETMKRMTGFRNIAVHDYQAVQVPIVMSIIRHQADDLIGYAKRMIQLA

Nucleotide

• Length: 411 bp

>T78534 NZ_CP022134:1553972-1554382 [Halomonas sp. HG01]
ATGGCCGATGACGTGCTGCTGAACAAGGCCGCCACGATCGAGCGATGCATCGGGCGTGCCAGGGAAGAGTACGACAAGGA
TCCCGACACCTTCGAGTCCGATCAGACGCGTCAGGATGCCGCCATCCTCAATCTGCAGCGTGCCTGCGAGGCGGCCATCG
ATGCGGGCAATCGCCTGGTGCGTCTGCAGCAGCTGGGATTGCCGCAGAGTGCGCGAGATGTCTTTTCGCTGCTGGTGCAG
GCGGACCTGCTCGATGAGGCGCTGGGTGAGACCATGAAGCGCATGACCGGCTTTCGGAACATCGCCGTGCATGACTATCA
GGCCGTCCAGGTGCCGATCGTGATGTCGATCATCCGCCATCAGGCCGATGACCTGATCGGCTACGCAAAGCGCATGATTC
AGCTGGCGTGA

Antitoxin

Protein

• Length: 137 a.a.
• Molecular weight: 15234.24 Da
• Isoelectric Point: 4.3299

>AT78534 WP_046078602.1 NZ_CP022134:1553572-1553982 [Halomonas sp. HG01]
MPLRPEDCQRCVESLRQALPALQAVYLFGSQATEMSRHDSDVDLAVLLPSAMASDQRWALAGTLASLLDRDVDLVDLRDA
STVMQYQVVSEGVPLWRAGTEADEFELAIFSEYWDLGIQRRALIEDIKQRGSIHGR

Nucleotide

• Length: 411 bp

>AT78534 NZ_CP022134:1553572-1553982 [Halomonas sp. HG01]
ATGCCGCTGAGACCGGAGGACTGCCAGCGCTGCGTCGAATCGCTGCGCCAGGCGTTGCCAGCGCTGCAGGCCGTCTATCT
GTTCGGCAGCCAGGCGACCGAGATGTCGCGACACGACAGCGACGTCGACCTGGCCGTTCTCCTGCCTTCGGCCATGGCAT
CCGACCAGCGCTGGGCGCTGGCGGGAACTCTCGCCAGCCTGCTGGATCGGGACGTCGATCTCGTGGATCTGCGAGACGCC
TCGACCGTCATGCAGTATCAGGTGGTCTCGGAAGGTGTGCCGCTGTGGCGTGCCGGCACCGAGGCCGACGAGTTCGAGCT
GGCCATATTCAGTGAGTACTGGGACCTCGGCATTCAGCGGCGTGCCCTGATCGAGGACATCAAGCAACGGGGAAGCATTC
ATGGCCGATGA