78533

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 898603..900350 Replicon chromosome
Accession NZ_CP022134
Organism Halomonas sp. HG01

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag UN84_RS04105 Protein ID WP_046077771.1
Coordinates 899694..900350 (-) Length 219 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag UN84_RS04100 Protein ID WP_046077772.1
Coordinates 898603..899697 (-) Length 365 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
UN84_RS04085 893865..894239 + 375 WP_202020710.1 MarR family transcriptional regulator -
UN84_RS04090 894501..895202 - 702 WP_046077774.1 M48 family metallopeptidase -
UN84_RS04095 895199..898576 - 3378 WP_046077773.1 type I restriction endonuclease subunit R -
UN84_RS04100 898603..899697 - 1095 WP_046077772.1 macro domain-containing protein Antitoxin
UN84_RS04105 899694..900350 - 657 WP_046077771.1 DUF4433 domain-containing protein Toxin
UN84_RS04110 900354..902165 - 1812 WP_046077770.1 DUF262 domain-containing protein -
UN84_RS04115 902223..903470 - 1248 WP_046077769.1 restriction endonuclease subunit S -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 892507..903470 10963


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-217)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 219 a.a.        Molecular weight: 24750.51 Da        Isoelectric Point: 7.9393

>T78533 WP_046077771.1 NZ_CP022134:c900350-899694 [Halomonas sp. HG01]
MATDLSRSLNARKGLIFRITHRDNLPWLLTNGLYCRSAEEQDPGFITIGNRELIGRRATREVPMPPGGTLSDYIPFYFTP
ASPMLLNIVTGRGVPIQSKQDILVLVCSLPRMQELGLPFVFTDRHAYMPLARFSNRLQDLAEFVPWQLLQAQDFSRDPED
PEKTERYQAEALVHHHLPASALLGIGTYTDEVRAAVEAQVAAHQLPLKVVTRPKWFFR

Download         Length: 657 bp

>T78533 NZ_CP022134:c900350-899694 [Halomonas sp. HG01]
ATGGCCACCGACCTCTCCCGTAGCCTGAATGCCCGCAAGGGCCTGATCTTTCGCATCACGCATCGCGATAATCTGCCGTG
GCTGCTGACAAACGGGCTCTACTGTCGGTCGGCCGAGGAGCAGGATCCGGGATTCATCACGATAGGCAATCGCGAGCTGA
TAGGACGGCGAGCGACTCGAGAGGTCCCCATGCCGCCTGGCGGCACGCTCAGCGATTACATTCCTTTCTACTTCACGCCC
GCCTCTCCGATGCTGCTCAACATCGTGACAGGGCGTGGCGTGCCTATCCAAAGCAAGCAGGACATCCTCGTGCTGGTCTG
CTCACTGCCACGTATGCAGGAATTGGGACTGCCCTTTGTCTTCACCGACCGGCACGCCTATATGCCCCTGGCCCGCTTTA
GCAACCGACTGCAGGATCTCGCGGAGTTCGTCCCTTGGCAGCTGTTGCAGGCGCAGGACTTCAGTCGAGATCCAGAAGAC
CCAGAGAAGACTGAGCGCTACCAGGCCGAGGCCCTCGTACATCACCATCTGCCGGCCTCGGCACTGCTTGGCATTGGCAC
GTATACTGATGAGGTCCGAGCCGCTGTAGAAGCACAGGTAGCGGCACACCAGCTTCCGCTGAAGGTGGTGACACGACCCA
AATGGTTCTTCCGATGA

Antitoxin


Download         Length: 365 a.a.        Molecular weight: 41535.76 Da        Isoelectric Point: 6.3252

>AT78533 WP_046077772.1 NZ_CP022134:c899697-898603 [Halomonas sp. HG01]
MIEYTRGNLIEADVEALVNTVNTVGVMGKGIALMFKESFPENFAAYAAACKHQEVATGRMFVTEREALLGPRWIINFPTK
QHWRARTRMEWIESGLEDLKRVIREQGIRSIALPPLGCGNGGLDWDRVRPRIEATLGELDNVRVLVFEPTAEYQNVAKRS
GVEKLTPARALIAELVRRYWVLGLECSLLEVQKLAWLMEQRIVAHGLDNPLRLEFQPHRYGPYSDRLRHLLNGMDGSYLH
SEKRINDASPEEVVWFDEPRRDRLHAYLRSREARAYAEVLEEVDVLIDGFQSPLGMEVLATLDWLISREGVEPSVEAVKE
GLRHWPDDVAGKRKLRLFSDRLIALALERLTGEAIPPLKLAAER

Download         Length: 1095 bp

>AT78533 NZ_CP022134:c899697-898603 [Halomonas sp. HG01]
ATGATTGAATACACCCGTGGCAACCTGATCGAGGCCGACGTTGAGGCGCTGGTCAACACCGTCAACACCGTGGGCGTAAT
GGGCAAGGGCATCGCCTTGATGTTCAAGGAGTCCTTCCCCGAGAACTTCGCGGCCTATGCGGCCGCCTGTAAGCACCAGG
AAGTGGCCACCGGGCGCATGTTCGTCACCGAGAGGGAGGCTCTGCTGGGCCCGCGCTGGATCATCAACTTCCCTACCAAG
CAGCACTGGCGCGCCAGAACGCGCATGGAGTGGATCGAGTCCGGTCTTGAGGACCTCAAGCGGGTGATCCGTGAACAGGG
CATTCGCTCCATCGCCCTGCCACCTCTGGGCTGCGGCAACGGGGGGCTCGACTGGGACCGGGTGCGCCCGCGCATCGAGG
CCACCCTGGGCGAACTGGATAATGTCCGAGTGCTGGTCTTTGAGCCCACAGCCGAATACCAGAACGTCGCCAAGCGCTCC
GGCGTCGAGAAGCTGACACCTGCACGTGCGCTGATCGCCGAGCTGGTGCGCCGCTACTGGGTGCTGGGCCTCGAGTGCTC
ACTGCTGGAGGTACAGAAGCTCGCCTGGCTGATGGAGCAGCGGATCGTCGCCCATGGCCTCGACAACCCCCTCAGGCTCG
AATTCCAGCCACACCGATATGGCCCTTACTCCGACCGGCTACGCCATCTCCTCAATGGCATGGACGGCAGCTATCTGCAT
AGCGAGAAACGCATCAACGACGCCTCTCCTGAGGAAGTGGTCTGGTTCGATGAGCCGCGGCGTGACCGACTGCATGCATA
TCTGCGCAGTCGAGAGGCCAGGGCCTATGCCGAAGTGCTCGAGGAGGTCGATGTTCTGATCGACGGTTTCCAGTCGCCGC
TAGGGATGGAGGTGCTGGCAACCCTGGACTGGCTGATTAGCCGGGAGGGCGTCGAGCCGTCCGTCGAGGCCGTCAAGGAA
GGGCTTCGGCATTGGCCCGATGATGTGGCCGGCAAGCGAAAGCTGCGCCTGTTCTCGGACCGCCTGATCGCGCTGGCGCT
GGAGCGCCTGACCGGTGAAGCTATTCCGCCCCTGAAACTAGCCGCCGAAAGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References