Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hipBA/HipA-HipB
Location 336774..338341 Replicon chromosome
Accession NZ_CP022133
Organism Idiomarina piscisalsi strain 10PY1A

Toxin (Protein)


Gene name hipA Uniprot ID -
Locus tag CEW91_RS01595 Protein ID WP_088767382.1
Coordinates 336774..338084 (-) Length 437 a.a.

Antitoxin (Protein)


Gene name hipB Uniprot ID -
Locus tag CEW91_RS01600 Protein ID WP_088767383.1
Coordinates 338084..338341 (-) Length 86 a.a.

Genomic Context

CEW91_RS01575CEW91_RS01580CEW91_RS01565CEW91_RS01570CEW91_RS01595CEW91_RS01600CEW91_RS01605CEW91_RS01610CEW91_RS01615
Location: 334349..334900 (552 bp)
Type: Others
Protein ID: WP_088767380.1
Location: 334940..336469 (1530 bp)
Type: Others
Protein ID: WP_088767381.1
Location: 332343..333191 (849 bp)
Type: Others
Protein ID: WP_088769327.1
Location: 333236..334279 (1044 bp)
Type: Others
Protein ID: WP_088767379.1
Location: 336774..338084 (1311 bp)
Type: Toxin
Protein ID: WP_088767382.1
Location: 338084..338341 (258 bp)
Type: Antitoxin
Protein ID: WP_088767383.1
Location: 338473..339618 (1146 bp)
Type: Others
Protein ID: WP_088767384.1
Location: 339664..340581 (918 bp)
Type: Others
Protein ID: WP_088767385.1
Location: 340585..342426 (1842 bp)
Type: Others
Protein ID: WP_088767386.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
CEW91_RS01565332343..333191-849WP_088769327.1phosphatidylserine decarboxylase-
CEW91_RS01570333236..334279-1044WP_088767379.1small ribosomal subunit biogenesis GTPase RsgA-
CEW91_RS01575334349..334900+552WP_088767380.1oligoribonuclease-
CEW91_RS01580334940..336469+1530WP_088767381.1BCCT family transporter-
CEW91_RS01595336774..338084-1311WP_088767382.1type II toxin-antitoxin system HipA family toxinToxin
CEW91_RS01600338084..338341-258WP_088767383.1helix-turn-helix domain-containing proteinAntitoxin
CEW91_RS01605338473..339618-1146WP_088767384.1dicarboxylate/amino acid:cation symporter-
CEW91_RS01610339664..340581-918WP_088767385.1histone deacetylase family protein-
CEW91_RS01615340585..342426-1842WP_088767386.1GNAT family N-acetyltransferase-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HipA, N-terminal subdomain 1

(4-103)

Antitoxin

Cro/C1-type helix-turn-helix domain

(13-64)


Sequences

Toxin        


Download         Length: 437 a.a.        Molecular weight: 49097.31 Da        Isoelectric Point: 8.5448

>T78531 WP_088767382.1 NZ_CP022133:c338084-336774 [Idiomarina piscisalsi]
MDKLDIYMNGLLVGELHRRHSGAHRFNYSINWLDTPGARPISLSMPLTRNAYEGAEVINFFDNLLPDSQEVRDRIVARYR
ADSKQPFDLLKAVGRDTVGALQFYPQGEQPGNIRTINYQPLNDSELEKVLLGYQSKAPLGMVNELNDFRISIAGAQEKTA
LLKIEDKWCIPEGTTPTSHIIKLPIGKIQGADHTIDLSDSVENELLCLEIAREFGFDVPACEIVNTGKVKALAVERFDRK
YSSDKSWLMRLPQEDYCQVLSCPSARKYESDGGPSIAQIMKHLQSSSNSHKDRRTFMAAQVLFFLLGATDGHAKNFSVFI
EPEGGFKLTPLYDILSAYPAVGGQGLHLRDLKLAMTLKGSKGRKSKLFQIYGRHFISSAKEAQYSLKEMQDILKLMHAST
DNVIERVSKRLPKDFPMKVSEPIFEGLSRRKERLIS

Download         Length: 1311 bp

>T78531 NZ_CP022133:c338084-336774 [Idiomarina piscisalsi]
ATGGATAAACTCGATATTTATATGAACGGGCTACTGGTCGGTGAGCTGCACCGTAGGCACTCTGGCGCCCACCGTTTTAA
CTACAGTATCAACTGGCTCGATACACCGGGCGCTCGCCCAATTTCGTTATCGATGCCTCTAACAAGAAACGCCTACGAAG
GTGCTGAAGTCATCAACTTTTTTGATAACCTCCTGCCCGATAGTCAGGAAGTTCGAGACAGGATTGTTGCGCGCTACCGA
GCCGACTCGAAACAACCTTTCGATCTTCTAAAAGCAGTAGGCCGAGATACAGTAGGCGCTTTACAGTTTTACCCTCAAGG
GGAACAACCTGGCAATATAAGGACAATAAACTACCAGCCTCTGAATGATAGCGAGCTAGAAAAGGTTCTTCTAGGCTATC
AGTCTAAGGCACCGCTTGGCATGGTGAATGAGCTCAATGACTTTCGTATATCGATAGCTGGAGCACAAGAGAAAACAGCG
TTACTTAAAATAGAAGATAAATGGTGTATTCCCGAAGGAACTACACCGACAAGCCACATCATCAAACTACCTATCGGAAA
GATCCAAGGAGCAGACCATACTATCGACTTATCCGACAGCGTTGAAAATGAGCTGCTGTGTCTGGAAATCGCCAGAGAAT
TCGGTTTCGACGTGCCCGCTTGTGAGATTGTTAACACAGGTAAGGTAAAAGCTCTGGCCGTAGAGCGCTTCGATCGCAAA
TATTCCAGTGATAAATCCTGGCTCATGCGCCTGCCGCAAGAGGATTACTGTCAGGTACTTAGCTGTCCTTCTGCTCGAAA
GTACGAGTCTGACGGCGGTCCGTCCATAGCGCAAATTATGAAGCACTTACAAAGCTCTTCTAACTCTCACAAAGACAGAA
GAACTTTTATGGCAGCACAGGTGCTATTTTTTCTGTTAGGAGCAACCGACGGGCACGCTAAAAACTTTTCTGTGTTTATA
GAGCCAGAAGGTGGTTTCAAATTAACTCCGCTTTACGACATTCTTTCGGCGTACCCAGCAGTCGGAGGTCAAGGGCTTCA
TTTAAGAGACTTAAAACTGGCGATGACACTTAAAGGCTCAAAAGGTCGAAAGTCAAAGCTTTTCCAGATTTACGGGCGTC
ATTTCATCAGTTCGGCAAAGGAAGCGCAGTACAGCCTAAAAGAGATGCAGGACATTCTTAAGCTAATGCATGCAAGCACA
GATAACGTTATTGAAAGGGTGAGTAAGCGCTTACCCAAAGACTTTCCGATGAAAGTTTCAGAGCCTATTTTTGAAGGTCT
TAGTCGTCGAAAAGAGAGGCTTATTAGCTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9617.73 Da        Isoelectric Point: 5.6175

>AT78531 WP_088767383.1 NZ_CP022133:c338341-338084 [Idiomarina piscisalsi]
MKITSPHALAVHLKDERKQQRLSQANVAESVGLRQGTVSSFELSPEKSQIDTLFRLLSALGLELSIKSKEDAQENNTEHS
WNEEW

Download         Length: 258 bp

>AT78531 NZ_CP022133:c338341-338084 [Idiomarina piscisalsi]
ATGAAAATTACAAGCCCCCACGCGTTAGCGGTTCATTTAAAAGATGAAAGAAAACAACAAAGATTAAGTCAGGCAAACGT
TGCTGAATCCGTTGGTTTAAGACAGGGCACTGTCTCAAGCTTTGAGCTTTCTCCAGAGAAAAGCCAAATAGATACGTTAT
TTCGGCTTCTATCAGCGCTTGGGCTAGAGTTAAGTATTAAGAGCAAGGAAGACGCTCAGGAAAACAACACTGAACACTCA
TGGAATGAGGAATGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References